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| 1 | Helicobacter pylori associated chronic gastritis,clinical syndromes,precancerous lesions,and pathogenesis of gastric cancer development显示文摘Helicobacter pylori(H.pylori)infection is well known to be associated with the development of precancerous lesions such as chronic atrophic gastritis(AG),or gastric intestinal metaplasia(GIM),and cancer.Various molecular alterations are identified not only in gastric cancer(GC)but also in precancerous lesions.H.pylori treatment seems to improve AG and GIM,but still remains controversial.In contrast,many studies,including meta-analysis,show that H.pylori eradication reduces GC.Molecular markers detected by genetic and epigenetic alterations related to carcinogenesis reverse following H.pylori eradication.This indicates that these changes may be an important factor in the identification of high risk patients for cancer development.Patients who underwent endoscopic treatment of GC are at high risk for development of metachronous GC.A randomized controlled trial from Japan concluded that prophylactic eradication of H.pylori after endoscopic resection should be used to prevent the development of metachronous GC,but recent retrospective studies did not show the tendency.Patients with precancerous lesions(molecular alterations)that do not reverse after H.pylori treatment,represent the'point of no return'and may be at high risk for the development of GC.Therefore,earlier H.pylori eradication should be considered for preventing GC development prior to the appearance of precancerous lesions. | Jiro Watari Nancy Chen Peter S Amenta Hirokazu Fukui Tadayuki Oshima Toshihiko Tomita Hiroto Miwa Kheng-Jim Lim Kiron M Das | 2014 | World Journal of Gastroenterology2014，20，18： | 60 |
| 2 | Modeling of cephalosporin C production and its application to fedbatch culture显示文摘 | Matsumura M Tadayuki I Toshiomi Y | 1981 | J Ferment Technol1981，59，2： | 1 |
| 3 | Sentinel node sam pling limits lymphadenectomy in stage I non-small cell lung cancer显示文摘 | Masashi M Shinji A Tadayuki O | 2007 | European Journal of Cardio-thoracic Surgery2007，32，7： | 1 |
| 4 | Sentinel node sampling limits lymphadeneetomy in stage I non-small cell lung cancer 显示文摘 | Masashi M Shinii A Tadayuki O | 2007 | Eur J Cardiothorac Surg2007，32，7： | 1 |
| 5 | A mixed distribution system of direct and relay delivery methods based on an analogy of milk - run logistics 显示文摘 | Masayuki G Tadayuki M Nobuhiko T | 2007 | Journal of Japan Industrial Management Association2007，58，2： | 1 |
| 6 | A mixed distribution system of direct and relay delivery methods based on an anology of milk-run logistics显示文摘 | Masayuki G Tadayuki M Nobuhiko T | 2007 | Journal of Japan Industrial Management Association2007，58，2： | 1 |
| 7 | Minimization of heat-affected zone size in welded ultra-fine grained steel under cooling by liquid nitrogen during laser welding显示文摘 | HIDEKI H YASUNOBU M TADAYUKI O | 2006 | Materials Science and Engineering: A2006，426，12： | 1 |
| 8 | High-albedo roof coating-impact on energy consumption显示文摘 | Tadayuki James M Akidge | 1998 | ASHREA Transactions1998，104，： | 1 |
| 9 | A barium-ti- tanate-eeramies capacitivetype EEG electrode 显示文摘 | TADAYUKI M KAZUHIRO I ESASHI M | | IEEE Trans Biomed Eng0，20，4： | 1 |
| 10 | Sequential fluorometric quantification of malic acid enantiomers by a single line flow-injection system using immobilized-enzyme reactors显示文摘 | Tadayuki T Kiyoshi M | 2005 | Talanta2005，65，2： | 1 |
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