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| 1 | Clinical value of rapid urine trypsinogen-2 test strip, urinary trypsinogen activation peptide, and serum and urinary activation peptide of carboxypeptidase B in acute pancreatitis显示文摘AIM: To assess the usefulness of urinary trypsinogen-2 test strip, urinary trypsinogen activation peptide (TAP),and serum and urine concentrations of the activation peptide of carboxypeptidase B (CAPAP) in the diagnosisof acute pancreatitis.METHODS: Patients with acute abdominal pain and hospitalized within 24 h after the onset of symptoms were prospectively studied. Urinary trypsinogen-2 was considered positive when a clear blue line was observed (detection limit 50 μg/L). Urinary TAP was measured using a quantitative solid-phase ELISA, and serum and urinary CAPAP by a radioimmunoassay method.RESULTS: Acute abdominal pain was due to acute pancreatitis in 50 patients and turned out to be extrapancreatic in origin in 22 patients. Patients with acute pancreatitis showed significantly higher median levels of serum and urinary CAPAP levels, as well as amylase and lipase than extrapancreatic controls. Median TAP levels were similar in both groups. The urinary trypsinogen-2 test strip was positive in 68% of patients with acute pancreatitis and 13.6% in extrapancreatic controls (P<0.01). Urinary CAPAP was the most reliable test for the diagnosis of acute pancreatitis (sensitivity 66.7%, specificity 95.5%, positive and negative predictive values 96.6% and 56.7%, respectively), with a 14.6 positive likelihood ratio for a cut-off value of 2.32 nmol/L.CONCLUSION: In patients with acute abdominal pain,hospitalized within 24 h of symptom onset, CAPAP in serum and urine was a reliable diagnostic marker of acute pancreatitis. Urinary trypsinogen-2 test strip showed a clinical value similar to amylase and lipase.Urinary TAP was not a useful screening test for the diagnosis of acute pancreatitis. | Jesús Sáez Juan Martínez Celia Trigo José Sánchez-Payá Luis Compay Raquel Laveda Pilar Grió Cristina García Miguel Pérez-Mateo | 2005 | World Journal of Gastroenterology2005，11，46： | 21 |
| 2 | Coronary angiography findings in cardiac arrest patients with non-diagnostic post-resuscitation electrocardiogram:A comparison of shockable and non-shockable initial rhythms显示文摘AIM To investigate the impact of coronary artery disease in a cohort of patients resuscitated from cardiac arrest with non-diagnostic electrocardiogram.METHODS From March 2004 to February 2016, 203 consecutive patients resuscitated from in or out-of-hospital sudden cardiac arrest and non-diagnostic post-resuscitation electrocardiogram(defined as ST segment elevation or pre-sumably new left bundle branch block) whounderwent invasive coronary angiogram during hospitalization were included. For purpose of analysis and comparison, patients were classified in two groups: Initial shockable rhythm(ventricular tachycardia or ventricular fibrillation; n = 148, 72.9%) and initial non-shockable rhythm(n = 55, 27.1%). Baseline characteristics, coronary angiogram findings including Syntax Score and long-term survival rates were compared. RESULTS Sudden cardiac arrest was witnessed in 95.2% of cases, 66.7% were out-of-hospital patients and 72.4% were male. There were no significant differences in baseline characteristics between groups except for higher mean age(68.1 years vs 61 years, P = 0.001) in the nonshockable rhythm group. Overall 5-year mortality of the resuscitated patients was 37.4%. Patients with non-shockable rhythms had higher mortality(60% vs 29.1%, P < 0.001) and a worst neurological status at hospital discharge based on cerebral performance category score(CPC 1-2: 32.7% vs 53.4%, P = 0.02). Although there were no significant differences in global burden of coronary artery disease defined by Syntax Score(mean Syntax Score: 10.2 vs 10.3, P = 0.96) there was a trend towards a higher incidence of acute coronary lesions in patients with shockable rhythm(29.7% vs 16.4%, P = 0.054). There was also a higher need for ad-hoc percutaneous coronary intervention in this group(21.9% vs 9.1%, P = 0.03). CONCLUSION Initial shockable group of patients had a trend towards higher incidence of acute coronary lesions and higher need of ad-hoc percutaneous intervention vs nonshockable group. | Pedro Martínez-Losas Pablo Salinas Carlos Ferrera María Teresa Nogales-Romo Francisco Noriega María Del Trigo Iván Javier Núnez-Gil Luis Nombela-Franco Nieves Gonzalo Pilar Jiménez-Quevedo Javier Escaned Antonio Fernández-Ortiz Carlos Macaya Ana Viana-Tejedor | 2017 | World Journal of Cardiology2017，9，8： | 3 |
| 3 | Maize and resistant starch enriched breads reduce postprandial glycemic responses in rats显示文摘 | Carla M. Brites Maria J. Trigo Belmira Carrapi?o Marcela Alvi?a Rui J. Bessa | 2011 | Nutrition Research2011，，4： | 1 |
| 4 | Evaluation of Prognostic Factors for Early Infection in Liver Transplantation显示文摘 | Cueto G Trigo P Arata A | 1999 | Transplant Proc1999，31，7： | 1 |
| 5 | Cell signalling of the GLP-1 action in rat liver显示文摘 | Redondo A Trigo M V Acitores A | 2003 | Mol Cell Endocrinol2003，204，12： | 1 |
| 6 | Simplified modu- lated evaporation process for the production of CulnS2 films with reduced substrate temperatures 显示文摘 | Bollero A Trigo J F Herrero J | 2009 | Thin Solid Films2009，517，7： | 1 |
| 7 | Evaluating the impact of extreme temperature based indices in the 2003 heatwave excessive mortality in Portugal显示文摘 | Trigo R M Ramos A M Nogueirac P J | | 0，，07： | 1 |
| 8 | Effect of GLP- 1 on D-glucose transport, lipolysis and lipogenesis in adipocytes of obese subjects显示文摘 | Sancho V Trigo MV Martin-Duce A | 2006 | Int J Mol Med2006，17，6： | 1 |
| 9 | The nature of innovation in R&D-and non- R&D-intensive service firms: evidence from firm-level la- tent class analysis显示文摘 | TRIGO A | 2013 | Industry and Innovation2013，20，1： | 1 |
| 10 | Scope and patterns of innovation cooperation in Spanish service enterprises显示文摘 | TRIGO A VENCE X | 2012 | Research Policy2012，4，13： | 1 |
| 11 | 5-Fluorouracil release from copolymeric hydrogels of itaconic acid monoester I: Acrylamide-co-monomethyl itaconate 显示文摘 | Blanco M D García O Trigo R M | 1996 | Biomaterials1996，17，： | 1 |
| 12 | Evidence of increasing drought severity caused by temperature rise in southern Europe显示文摘 | Sergio M Vicente-Serrano Juan-I Lopez-Moreno Santiago Beguería Jorge Lorenzo-Lacruz Arturo Sanchez-Lorenzo José M García-Ruiz Cesar Azorin-Molina Enrique Morán-Tejeda Jesús Revuelto Ricardo Trigo Fatima Coelho Francisco Espejo | 2014 | Environmental Research Letters2014，，4： | 1 |
| 13 | Diversity of innovation patterns in services显示文摘 | VENCE X TRIGO A | 2009 | The Service Industries Journal2009，29，12： | 1 |
| 14 | Discharge profi les of abducens,accessory abducens,and orbicularis oculi motoneurons during reflex and conditioned blinks in alert cats显示文摘 | Trigo JA Gruart A Delgado-Garcia JM | | 0，，： | 1 |
| 15 | Evolution of extreme temperatures over Portugal: recent changes and future scenarios显示文摘 | Ramos A M Trigo R M Santo F E | 2011 | Climate Research2011，48，23： | 1 |
| 16 | Scope and Patterns of Innovation Cooperation in Spanish Service Enterprises 显示文摘 | Trigo A Vence X | 2012 | Research Policy2012，41，3： | 1 |
| 17 | Latanoprost and brimonidine: therapeutic and physiologic assessment before and after oral nonsteroidal anti-inflammatory therapy显示文摘 | Sponsel WE Paris G Trigo Y Pena M Weber A Sanford K | 2002 | Am J Ophthalmol2002，133，1： | 1 |
| 18 | Evaluation of prognostic factors for early infection in liver transplantation显示文摘 | Cueto G Trigo P Arata A | 1999 | Transplant Proc1999，31，： | 1 |
| 19 | Optimisation of the Preventive Maintenance Plan of a Series Components System 显示文摘 | Duarte J A C Craveiro J C T A Trigo T P | 2006 | International Journal of Pressure Vessels and Piping2006，83，4： | 1 |
| 20 | Cell signalling of the GLP-1 action in rat liver显示文摘 | Redondo A Trigo MV Acitores A | 2003 | Mol Cell Endocrinol2003，204，12： | 1 |
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