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    题名 作者 年代 出处 被引量
1Induced isoflavonoids in diverse population of Astragalus cicer 显示文摘MARTIN SS TOWNSEND CE Lenscen AW 1994Biochemical Systematics and Ecology1994,22,:1
2Improving diabetic and hypertensive retinopathy with a medical food containing L-methylfolate: a preliminary report显示文摘Background:Homocysteine and vitamin D may play a role in the development of diabetic and hypertensive retinopathy in patients with diabetes mellitus(DM)and hypertension.Supplementing food with L-methylfolate and vitamin D theoretically may improve diabetic and hypertensive retinopathy,however,the outcome of these nutritional approaches has not been fully examined.A retrospective case review was done of cases of retinopathy reversal in patients on Ocufolin^(TM) and a similar nonprescription multivitamin,Eyefolate^(TM).In this study,they were administered L-methylfolate(2.7 mg and 3.0 mg,respectively)and vitamin D3(4500 IU each).These dosages are significantly above the RDA but well below levels associated with toxicity.Case presentation:Seven patients had nonproliferative diabetic retinopathy(NPDR)and some of them had hypertension.One patient had only hypertensive retinopathy.All patients were instructed to take Ocufolin^(TM)medical food as a food supplement.Baseline genetic testing for MTHFR polymorphisms was conducted.Fundus photography was used to document the fundus condition of the enrolled eyes in 8 NPDR patients at the initial and follow-up visits.Microaneurysms(MA)and exudates were observed to be improved in some trial patients.All subjects had one or more MTHFR polymorphisms.All had diabetic retinopathy,hypertensive retinopathy,or both.MAs were resolved,and exudates were decreased in 8/8 cases after taking the medical food.Retinal edema was found in 2/8 cases and improved or resolved in both cases after taking the medical food or the supplement.The best corrected visual activity was stable or improved in 8/8 cases.Conclusion:We report a series of diabetic and hypertensive retinopathy cases with MTHFR polymorphisms and the improvement of retinal microvasculature(mainly MAs)in serial fundus photography after taking a medical food or supplement containing L-methylfolate and vitamin D.It appears that the use of nutritional supplements and medical foods containing L-methylfolate and vitamin D may be effective in facilitating the improvement of diabetic and hypertensive retinopathy.Jianhua Wang Craig Brown Ce Shi Justin Townsend Giovana Rosa Gameiro Peng Wang Hong Jiang 2019Eye and Vision2019,6,1:1
3Organ donor management and organ outcome:a 6-year review from a Level I trauma eentor显示文摘Nyganrd CE Townsend RN Diamond DL 1990J Trauma1990,30,6:1
4进展性慢性肾脏病和血液透析患者的血压与全因死亡风险:慢性肾功能不全队列研究显示文摘研究表明,透析患者收缩压和死亡率的关系呈U形曲线。这些研究很大程度上依赖于透析时测量的收缩压,且并未评估在进展性慢性肾脏病患者透析前是否也存在U形曲线关系。该研究旨在确定未透析时和开始透析后进展性慢性肾脏病患者收缩压和死亡率间的关系。Bansal N McCulloch CE Rahman M Kusek JW Anderson AH Xie D Townsend RR Lora CM Wright J Go AS Ojo A Alper A Lustigova E Cuevas M Kallem R Hsu CY 刘莉 叶鹏 2014中华高血压杂志2014,22,10:0
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