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| 1 | Subcycle control of terahertz waveform polarization using all-optically induced transient metamaterials显示文摘Coherent radiation with frequencies ranging from 0.3 to 30 THz has recently become accessible using femtosecond laser technology.These terahertz(THz)waves have already been applied in spectroscopy and imaging and can be manipulated using static optical elements such as lenses,polarizers and filters.However,ultrafast modulation of THz radiation is required as well,for instance,in short-range wireless communication or for preparing shaped THz transients for the coherent control of numerous material excitations.Here,we demonstrate an all-optically created transient metamaterial that allows us to manipulate the polarization of THz waveforms with subcycle switch-on times.The polarization-modulated pulses are potentially interesting for controlling elementary motions such as the vibration of crystal lattices,the rotation of molecules and the precession of spins. | N Kamaraju Andrea Rubano Linke Jian Surajit Saha T Venkatesan Jan Notzold R Kramer Campen Martin Wolf Tobias Kampfrath | 2014 | Light(Science & Applications)2014，3，1： | 5 |
| 2 | Human immune cells' behavior and survival under bioenergetically restricted conditions in an in vitro fracture hematoma model显示文摘骨头骨折愈合的起始的煽动性的阶段为愈合的过程的结果代表关键步。然而,开始这个煽动性的阶段的机制和在破裂地点在场的有免疫力的房间的功能糟糕被理解。以便在破裂 hematoma 以内学习早事件,我们建立了一在里面 vitro 破裂 hematoma 模型:我们有教养的 hematomas 在 bioenergetically 控制的条件下面在 vitro 在全部的新潮的关节造形术(THA ) 期间在腿节的截骨术(人工的骨头破裂) 期间形成。这个模型允许我们在跟随破裂的早阶段期间监视有免疫力的房间人口,房间幸存和 cytokine 表示。而且,这个模型使我们能改变 bioenergetical 条件以便模仿在里面 vivo 状况,它被假定被组织缺氧描绘并且限制了营养素的数量。用这个模型,我们发现有免疫力的房间经由 angiogenic 因素, chemoattractants 和支持 inflammatory 分子的表示适应组织缺氧。另外,联合了氧的限制,滋养的供应与 myeloid 的比较提高了淋巴细胞的选择幸存导出的房间(即, neutrophils ) 。笔记,非限制的 bioenergetical 条件没关于 cytokine 表示或有免疫力的房间子集的不同幸存率显示出任何类似的效果。在结论,我们发现 bioenergetical 条件在导致骨折愈合的起始的煽动性的阶段的关键因素之中并且因此是为在早破裂 hematoma 影响有免疫力的房间的幸存和功能的一个关键步骤。 | Paula Hoff Patrick Maschmeyer Timo Gaber Tabea Schiitze Tobias Raue Katharina Schmidt-Bleek Rene Dziurla Saskia Schellmann Ferenz Leonard Lohanatha Eric Rohner Andrea Ode Gerd-Riidiger Burmester Georg N Duda Carsten Perka Frank Buttgereit | 2013 | Cellular & Molecular Immunology2013，10，2： | 3 |
| 3 | Genetic Variation in IL28B Is Associated With Chronic Hepatitis C and Treatment Failure: A Genome-Wide Association Study显示文摘 | Andri Rauch Zoltán Kutalik Patrick Descombes Tao Cai Julia Di Iulio Tobias Mueller Murielle Bochud Manuel Battegay Enos Bernasconi Jan Borovicka Sara Colombo Andreas Cerny Jean–Fran?ois Dufour Hansjakob Furrer Huldrych F. Günthard Markus Heim Bernard Hirs | 2010 | Gastroenterology2010，，4： | 2 |
| 4 | The APN'sguide to pediatric constipation management 显示文摘 | Mason D Tobias N Lutkenhoff M | 2004 | Nurse Pract2004，29，7： | 1 |
| 5 | The APN's guide to ped- iatric constipation management显示文摘 | Mason D Tobias N Lutkenhoff M et a l | 2004 | The Nurse Practitioner2004，29，7： | 1 |
| 6 | Age dependence of cellular properties of human septal cartilage: implications for tissue engineering显示文摘 | Rotter N Bonassar LJ Tobias G | 2001 | Arch Otolaryngol Head Neck Surg2001，127，10： | 1 |
| 7 | Characterization of R-synuclein interactions with selected aggregation-inhibiting small molecules显示文摘 | JAMPANI N R VARUN D TOBIAS S U | 2008 | Biochemistry2008，47，： | 1 |
| 8 | Stimulation of TNF receptor type 2 expands regulatory T cells and ameliorates established collagen-induced arthritis in mice显示文摘Tumor necrosis factor(TNF)and its receptors TNF receptor type 1(TNFR1)and type 2(TNFR2)have a central role in chronic inflammatory diseases.While TNFR1 mainly confers inflammation,activation of TNFR2 elicits not only pro-inflammatory but also anti-inflammatory effects.In this study,we wanted to investigate the anti-inflammatory therapeutic potential of selective activation of TNFR2 in mice with established collageninduced arthritis.Mice with established arthritis induced by immunization with bovine collagen type II were treated with six injections of the TNFR2-specific agonist TNCscTNF80,given every second day.Two days after treatment cessation,the cell compositions of bone marrow,spleen and lymph nodes were analyzed.Mice were visually scored until day 30 after the start of therapy and the degree of joint inflammation was determined by histology.Treatment with TNCscTNF80 increased arthritis-induced myelopoiesis.Little effect was seen on the infiltration rate of inflammatory immature myeloid cells and on the reduction of lymphoid cells in secondary lymphoid organs.Upon treatment,frequency of regulatory T(Treg)cells in the CD4+T-cell population was increased in both spleen and inguinal lymph nodes.In addition,the expression of TNFR2 on Treg cells was enhanced.The clinical score started to improve 1 week after cessation treatment and remained lower 30 days after initiation of therapy.The histological score also revealed amelioration of joint inflammation in TNCscTNF80-treated versus control mice.Activation of TNFR2 might provide a suitable therapeutic strategy in autoimmune arthritis by increasing the numbers of regulatory cell types,in particular Treg cells,and by attenuation of arthritis. | Vanessa Lamontain Tobias Schmid Dorothea Weber-Steffens David Zeller Zsuzsa Jenei-Lanzl Harald Wajant Rainer H Straub Daniela N Männel | 2019 | Cellular & Molecular Immunology2019，16，1： | 1 |
| 9 | Odontoblast stimulation in ferrets by dentine matrix components 显示文摘 | Smith AJ Tobias RS Cassidy N | 1994 | Arch Oral Biol1994，39，1： | 1 |
| 10 | Angiotensin II sustains brain inflammation in mice via TGF-[Beta]显示文摘 | Lanz Tobias V Ding Zhaoqing Ho Peggy P Luo Jian Agrawal Ankur N Srinagesh Hrishikesh Axtell Robert Zhang Hui Platten Michael Wyss-Coray Tony Steinman Lawrence | 2010 | Journal of Clinical Investigation2010，，8： | 1 |
| 11 | Long-term follow-up HbeAG-Positive Patients treated with interferon alfa for chronic hepatitis B显示文摘 | CLASUS N TOBIAS H STAFAN L | 1996 | New Engl J Med1996，334，4： | 1 |
| 12 | Resveratrol reduces endothelial oxidative stressby modulating the gene expression of superoxide dis-mutase 1 (SOD1),glutathione peroxidase 1 (GPxl )and NADPH oxidase subunit (Nox4 )显示文摘 | Spanier G Xu H Xia N? Tobias S Deng S WojnowskiL | 2009 | J PhysiolPharmacol2009，60，4： | 1 |
| 13 | Effects of annealing on the uanomorphology and performance of poly(alkylthiophene) : fullerene bulk-hetero- junction solar cells 显示文摘 | Le H N Harald H Tobias E | 2007 | Adv Fun Mater2007，17，7： | 1 |
| 14 | The role of different anesthetic techniques in altering the stress response during cardiac surgery in children: a prospective, double- blinded, and randomized study 显示文摘 | NAGUIB A N TOBIAS J D HALL M W | 2013 | Pediatr Crit Care Med2013，14，5： | 1 |
| 15 | lmmunoadsorbtion and rituximab therapy in a second living-related kidney transplant patient with recurrent focal segmental glomerulosclerosis 显示文摘 | Meyer Tobias N Thaiss | 2007 | Transplant International2007，20，12： | 1 |
| 16 | Odontoblast stimulation in ferrets by dentine matrix components显示文摘 | SmithA J Tobias R S Cassidy N | 1994 | Areh Ora Biol1994，39，1： | 1 |
| 17 | Diurnal variationsin hydraulic conductivity and root pressure can be correlated with the expression of putative aquaporins in the roots of lotus japonieus显示文摘 | Tobias Henzler Rosemary N Waterhouse | 1999 | Planta1999，210，： | 1 |
| 18 | T cells with a CD4^+ CD25^+ regulatory phenotype suppress in vitro proliferation of virusspecific CD8^+ T cells during chronic hepatitis C virus infection显示文摘 | Tobias B Hans C S Christoph N H | 2005 | J Virol2005，79，12： | 1 |
| 19 | Triose phosphate export from chloroplasts and cellular sugar content regulate anthocyanin biosynthesis during high light acclimation显示文摘Plants have evolvedmultiple strategies to cope with rapid changes in the environment.During high light(HL)acclimation,the biosynthesis of photoprotective flavonoids,such as anthocyanins,is induced.However,the exact nature of the signal and downstreamfactors forHL induction of flavonoid biosynthesis(FB)is still under debate.Here,we show that carbon fixation in chloroplasts,subsequent export of photosynthates by triose phosphate/phosphate translocator(TPT),and rapid increase in cellular sugar content permit the transcriptional and metabolic activation of anthocyanin biosynthesis during HL acclimation.In combination with genetic and physiological analysis,targeted and whole-transcriptome gene expression studies suggest that reactive oxygen species and phytohormones play only a minor role in rapid HL induction of the anthocyanin branch of FB.In addition to transcripts of FB,sugar-responsive genes showed delayed repression or induction in tpt-2 during HL treatment,and a significant overlapwith transcripts regulated by SNF1-related protein kinase 1(SnRK1)was observed,including a central transcription factor of FB.Analysis of mutants with increased and repressed SnRK1 activity suggests that sugar-induced inactivation of SnRK1 is required for HL-mediated activation of anthocyanin biosynthesis.Our study emphasizes the central role of chloroplasts as sensors for environmental changes as well as the vital function of sugar signaling in plant acclimation. | Max-Emanuel Zirngibl Galileo Estopare Araguirang Anastasia Kitashova Kathrin Jahnke Tobias Rolka Christine Kühn Thomas Nägele Andreas S.Richter | 2023 | Plant Communications2023，4，1： | 1 |
| 20 | A Theory of Nonlinear Regenerative Chatter 显示文摘 | Hanna N H Tobias S A | 1974 | Journal of Engineering for Industry1974，96，7： | 1 |
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