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	题名	作者	年代	出处	被引量
1	Alcohol metabolites and lipopolysaccharide: Roles in the development and/or progression of alcoholic liver disease显示文摘The onset of alcoholic liver disease (ALD) is initiated by different cell types in the liver and a number of different factors including: products derived from ethanol-induced inflammation, ethanol metabolites, and the indirect reactions from those metabolites. Ethanol oxidation results in the production of metabolites that have been shown to bind and form protein adducts, and to increase inflammatory, fibrotic and cirrhotic responses. Lipopolysaccharide (LPS) has many deleterious effects and plays a significant role in a number of disease processes by increasing inflammatory cytokine release. In ALD, LPS is thought to be derived from a breakdown in the intestinal wall enabling LPS from resident gut bacterial cell walls to leak into the blood stream. The ability of adducts and LPS to independently stimulate the various cells of the liver provides for a two-hit mechanism by which various biological responses are induced and result in liver injury. Therefore, the purpose of this article is to evaluate the effects of a two-hit combination of ethanol metabolites and LPS on the cells of the liver to increase inflamma-tion and fi brosis, and play a role in the development and/or progression of ALD.	Courtney S Schaffert Michael J Duryee Carlos D Hunter Bartlett C Hamilton 3rd Amy L DeVeney Mary M Huerter Lynell W Klassen Geoffrey M Thiele	2009	World Journal of Gastroenterology2009，15，10：	20
2	A vital sugar code for ricin toxicity显示文摘	Jasmin Taubenschmld Johannes Stadlmann Markus Jost Tove Irene Klok.k Cory D Rillahan Andreas Leibbrandt Karl Mechtler James C Paulson Julian Jude Johannes Zuber Kirsten Sandvig Ulrich Elling Thorsten Marquardt Christian Thiel Christian Koerner Josef M Penninger	2017	Cell Research2017，27，11：	2
3	The role of aluminum species in biphasic butene dimerization catalyzed by nickel complexes 显示文摘	Thiele D de Souza R F	2006	J Mol Catal A: Chem2006，264，：	1
4	The anharmonic force fields of HOF and F2O显示文摘	Thiel W Scuseria G Allen W D	1988	J Chem Phys1988，89，8：	1
5	The 2008 revision of the WHO classification of myeloid neoplasms and acute leukemia:rationale and important changes显示文摘	Vardiman J W Thiele J Arber D A	2009	Blood2009，114，5：	1
6	Adaptive power management for environmentally powered systems显示文摘	Moser C Thiele L BruneUi D	2010	Computers IEEE Transactions2010，59，49：	1
7	Correlation of radiographic renal cell carcinoma tumor volume utilizing computed tomography and magnetic resonance imaging compared with pathological tumor volume显示文摘	JORNS J THIEL D LOHSE C	2014	Scand J Urol2014，48，5：	1
8	Life sustaining treatment preferences of hemodialysis patients:implications for advance direc- tives显示文摘	Singer P A Thiel E C Naylor C D	1995	J AmSoc Nephrol1995，6，5：	1
9	H epatitisB and C in pregnancy: a review and recom m endations forcare显示文摘	D unkelberg JC Berkley E M Thiel K W	2014	J P erinatol2014，34，12：	1
10	HLA typing demands for peptide-based anti-cancer vaccine 显示文摘	Nagorsen D Thiel E	2008	Cancer Immunol Immunother2008，57，12：	1
11	Uptake of the anticancer drug cisplatin mediated by the copper transporter Ctr1 in yeast and mammals显示文摘	ISHIDA S LEE J THIELE D J	2002	Proc Natl Acad Sci U S A2002，99，14：	1
12	The chemistry and biological effects of malondisldehyde-acetaldehyde adducts 显示文摘	Thiele GM Worrall S Tuma D	2001	Alcohol Clin Exp Red2001，，25：	1
13	Long-term results of treatment for ureteroenteric strictures 显示文摘	DiMarco D S LeRoy A J Thieling S	2001	58(6):909-9132001，58，6：	1
14	Copper-specific transcriptional repression of yeast genes encoding crit-ieal components in the copper transport pathway显示文摘	Labbe S Zhu H W Thiele D J	1997	J Biol Chem1997，272，15：	1
15	Identification of a vacuole-associated metalloreductase and its role in Ctr2-mediated intracellular copper mobilization显示文摘	Rees E M Thiele D J	2007	J Biol Chem2007，282，21：	1
16	Gender imbalance in living kidney donation in Switzerland 显示文摘	Thiel G T Nolte C Tsinalis D	2005	Transplant Proc2005，37，2：	1
17	Rational synthesis of metastable skutterudite compounds using multilayer precursors显示文摘	HORNBOSTEL M D HYER E J THIEL J	1997	Journal of American Chemical Society1997，119，：	1
18	Fusarium moniliforme and fumonisins in corn in relation to human oesophageal cancer in Transkei显示文摘	Rheeder J P Marasas W F O Thiel P G Sydenham E W Shephard G S Van Schalkwyk D J	1992	Phytopathology1992，82，：	1
19	Mobilization of intracellular copper stores by the Ctr2 vacuolar copper transporter显示文摘	Rees E Lee J Thiele D J	2004	Journal of Biological Chemistry2004，279，54：	1
20	Mechanisms for copper acquisition,distribution and regulation显示文摘	Kim B E Nevitt T Thiele D J	2008	Nature Chemical Biology2008，4，3：	1

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