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| 1 | Percutaneous microwave ablation vs radiofrequency ablation in the treatment of hepatocellular carcinoma显示文摘Hepatocellular cancer ranks fifth among cancers and is related to chronic viral hepatitis, alcohol abuse,steatohepatitis and liver autoimmunity. Surgical resection and orthotopic liver transplantation have curative potential, but fewer than 20% of patients are suitable candidates. Interventional treatments are offered to the vast majority of patients. Radiofrequency(RFA) and microwave ablation(MWA) are among the therapeutic modalities, with similar indications which include the presence of up to three lesions, smaller than 3 cm in size, and the absence of extrahepatic disease. The therapeutic effect of both methods relies on thermal injury, but MWA uses an electromagnetic field as opposed to electrical current used in RFA. Unlike MWA, the effect of RFA is partially limited by the heat-sink effect and increased impedance of the ablated tissue. Compared with RFA, MWA attains a more predictable ablation zone, permits simultaneous treatment of multiple lesions, and achieves larger coagulation volumes in a shorter procedural time. Major complications of both methods are comparable and infrequent(approximately 2%-3%), and they include haemorrhage, infection/abscess, visceral organ injury, liver failure, and pneumothorax. RFA may incur the additional complication of skin burns. Nevertheless, there is no compelling evidence for differences in clinical outcomes, including local recurrence rates and survival. | Loukia S Poulou Evanthia Botsa Ioanna Thanou Panayiotis D Ziakas Loukas Thanos | 2015 | World Journal of Hepatology2015，7，8： | 37 |
| 2 | Thermal Ablation in the Management of Adrenal Metastasis Originating from Non-small Cell Lung Cancer: A 5-year Single-center Experience显示文摘 | Evanthia I Botsa Ioanna L Thanou Aspasia T Papatheodoropoulou Loukas I Thanos | 2017 | Chinese Medical Journal2017，，17： | 6 |
| 3 | Biodegradation, biodistribution and toxicity of chitosan显示文摘 | T. Kean M. Thanou | 2009 | Advanced Drug Delivery Reviews2009，，1： | 2 |
| 4 | N-sulfonato-N, O- carboxymethylchitosan: A novel polymeric absorption enhancer for the oral delivery of macromolecules 显示文摘 | Thanou M Henderson S Kydonieus A | 2007 | J Control Release2007，117，2： | 1 |
| 5 | Chitosan and its derivatives as intestinal absorption enhancers显示文摘 | Thanou M Verhoef JC Junginger HE | 2001 | Adv Drug Del Rev2001，50，： | 1 |
| 6 | Mono-N-carboxymethyl chitosan (MCC), a polyampholytic chitosan derivative enhances the intestinal absorption of low molecular weight heparin across intestinal epithelia in vitro and in vivo显示文摘 | Thanou M Nihot M T Jansen M | 2001 | J Pharm Sci2001，90，1： | 1 |
| 7 | Chitosan and its derivatives as intestinal absorption enhancers显示文摘 | Thanou M Verhoef JC Junginge HE | 2001 | Adv Drug Ddiv Rev2001，50，1： | 1 |
| 8 | Biodegradation, biodistribution and toxicity of chitosan显示文摘 | Kean T Thanou M | 2010 | Adv Drug Deliv Rev2010，62，1： | 1 |
| 9 | Oral drug absorption enhancement by chitesan and its derivatives显示文摘 | Thanou M Verhoef JC Junginge HE | 2001 | Adv Drug Dellv Rev2001，52，2： | 1 |
| 10 | Trimethylated chitosans as non-viral gene delivery vectors:cytotoxicity and transfection efficiency显示文摘 | Kean T Roth S Thanou M | | 0，，03： | 1 |
| 11 | Enhancement of paracellular drug transport with highly quaternized N - trimethyl chitosan chloride in neutral environnments: in vitro evaluation in intestinal epithelial cells (Caco22) 显示文摘 | Kotze AF Thanou MM Lueben HL | 1999 | J Pharm Sci1999，88，2： | 1 |
| 12 | N - trimethyl chitosan chloride (TMC) improves the intestinal permeation of the peptide drug buserelin in vitro (Caco2 - cell ) and in vivo (rats) 显示文摘 | Thanou M Florea BI Langemeyer MWE | 2000 | Pharm Res2000，17，1： | 1 |
| 13 | Enhancement of paracellular drug transport with highly quatemized N-trimethyl chitosan chloride in neutral environnments: in vitro evaluation in intestinal epithelial cells(Caco-2)显示文摘 | Kotze A F Thanou M M Luessen H L | 1999 | J Pharm Sci1999，88，2： | 1 |
| 14 | Preparation and NMR characterization of highly substituted N-trimethyl chitosan chloride显示文摘 | SIEVAL A B THANOU M KOTZE A F | 1998 | Carbohyd Polym1998，36，23： | 1 |
| 15 | Quaternized chitosan oligomers as novel gene delivery vectors in epithelial cell lines 显示文摘 | Thanou M Florea BI Geldof M | 2002 | MBiomaterials2002，23，1： | 1 |
| 16 | Biodegradation,biodistribution and toxicity of chitosan显示文摘 | KEAN T THANOU M | | 0，，1： | 1 |
| 17 | Trimethylated chitosans as non-viral gene delivery vectors: Cytotoxicity and transfection efficiency 显示文摘 | Thomas Kean Susanne Roth Maya Thanou | 2005 | Journal of Controlled Release2005，103，： | 1 |
| 18 | Biodegradation, distributima and toxicity of chitosan 显示文摘 | KEAN T THANOU M | 2010 | Adv Drug Deliv Rev2010，62，1： | 1 |
| 19 | Biodegradation,biodistribution and toxicity of chitosan 显示文摘 | KEAN T THANOU M | 2010 | Advanced Drug Delivery Reviews2010，62，1： | 1 |
| 20 | Effect of degree of quatemizadon of N-trimethyl chitosan chloride for enhanced transport of hydrophilic compounds across intestinal Caco-2 cell monolayers显示文摘 | Thanou M Kotze AF Scharringhausen T | 2000 | J Control Release2000，64，： | 1 |
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