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| 1 | Effect of selected signals of interest on ultrasonic backscattering measurement in cancellous bones显示文摘This study examined how the signals of interest (SOI) effect on the backscattering measurement numerically based on 3-D finite-difference time-domain (FDTD) method. High resolution microstructure mappings of bovine cancellous bones provided by micro-CT were used as the input geometry for simulations. Backscatter coefficient (BSC), integrated backscatter coefficient (IBC) and apparent integrated backscatter (AIB) were calculated with changing the start (L1) and duration (L2) of the SOI. The results demonstrated that BSC and IBC decrease as L1 increases, and AIB decreases more rapidly as L1 increases. The backscattering parameters increase with fluctuations as a function of L2 when L2 is less than 6 mm. However, BSC and IBC change little as L2 continues to increase, while AIB slowly decreases as L2 continues to increase. The results showed how the selections of the SOI effect on the backscattering measurement. An explicit standard for SOI selection was proposed in this study and short L1 (about 1.5 mm) and appropriate L2 (6 mm-12 mm) were recommended for the calculations of backscattering parameters. | LIU ChengCheng HAN HaiJie TA DeAn WANG WeiQi | 2013 | Science China(Physics,Mechanics & Astronomy)2013，56，7： | 10 |
| 2 | Joint spectrogram segmentation and ridge-extraction method for separating multimodal guided waves in long bones显示文摘Ultrasonic guided waves (GWs) can be used to evaluate long bones effectively because of the ability to provide the information of the whole bone. In this study, a joint spectrogram segmentation and ridge-extraction (JSSRE) method was proposed to separate multiple modes in long bones. First, the Gabor time-frequency transform was applied to obtain the spectrogram of multimodal signals. Then, a multi-class image segmentation algorithm was used to find the corresponding region of each mode in the spectrogram, including an improved watershed transform and a region growing procedure. Finally, the ridges were extracted and the time domain signals representing individual modes were reconstructed from these ridges in each region. The validations of this method were discussed by simulated multimodal signals with different signal-to-noise ratios (SNR). The correlation coefficients between the original signals without noise and the reconstructed signals were calculated to analyze the results quantitatively. The results showed that the extracted ridges were in good agreement with generated theoretical dispersion curves, and the reconstructed signals were highly related to the original signals, even under the SNR=3 dB situation. | ZHANG ZhengGang XU KaiLiang TA DeAn WANG WeiQi | 2013 | Science China(Physics,Mechanics & Astronomy)2013，56，7： | 10 |
| 3 | An Ultrasonic Backscatter Instrument for Cancellous Bone Evaluation in Neonates显示文摘Ultrasonic backscatter technique has shown promise as a noninvasive cancellous bone assessment tool. A novel ultrasonic backscatter bone diagnostic(UBBD) instrument and an in vivo application for neonatal bone evaluation are introduced in this study. The UBBD provides several advantages, including noninvasiveness, nonionizing radiation, portability, and simplicity. In this study, the backscatter signal could be measured within 5 s using the UBBD. Ultrasonic backscatter measurements were performed on 467 neonates(268 males and 199 females) at the left calcaneus. The backscatter signal was measured at a central frequency of 3.5 MHz. The delay(T_1) and duration(T_2) of the backscatter signal of interest(SOI) were varied, and the apparent integrated backscatter(AIB), frequency slope of apparent backscatter(FSAB), zero frequency intercept of apparent backscatter(FIAB), and spectral centroid shift(SCS) were calculated. The results showed that the SOI selection had a direct influence on cancellous bone evaluation. The AIB and FIAB were positively correlated with the gestational age(|R| up to 0.45, P < 0.001) when T_1 was short(< 8 μs), while negative correlations(|R| up to 0.56, P < 0.001) were commonly observed for T_1 > 10 μs. Moderate positive correlations(|R| up to 0.45, P < 0.001) were observed for FSAB and SCS with gestational age when T_1 was long(> 10 μs). The T_2 mainly introduced fluctuations in the observed correlation coefflcients. The moderate correlations observed with UBBD demonstrate the feasibility of using the backscatter signal to evaluate neonatal bone status. This study also proposes an explicit standard for in vivo SOI selection and neonatal cancellous bone assessment. | Chengcheng Liu Rong Zhang Ying Li Feng Xu Dean Ta Weiqi Wang | 2015 | Engineering2015，1，3： | 2 |
| 4 | The intraflagellar transport protein, IFT88, is essential for vertebrate photo- receptor assembly and maintenance显示文摘 | Pazour GJ Baker SA Deane TA | 2002 | J Cell Biol2002，157，1： | 1 |
| 5 | The persistent fetal carotid- vertebrobasilar anastomoses 显示文摘 | Luh GY Dean BL Tomsick TA | 1999 | AIR1999，172，： | 1 |
| 6 | Three-dimensional ultrasound subwavelength arbitrary focusing with broadband sparse metalens显示文摘Ultrasound focusing in three-dimensional(3 D)space is of crucial and enduring significance in a variety of biomedical and industrial applications.Conventional ultrasound focusing based on active phase array or passive geometry of bulky size is unable to realize the 3 D arbitrary focusing with subwavelength resolution.Acoustic metamaterial of complex deep-subwavelength microstructure has facilitated the advanced airborne-sound-focusing but is inevitably not applicable for underwater ultrasound,restricted by the law between the multi-modes coupling/thermal viscosity and the feature size of the structure.Here,we aim to circumvent the restriction by increasing the feature size of the metamaterial while keeping the compact overall geometry,and realize the robust subwavelength ultrasound focusing with the sparse metalens of the wavelength-scale meta-atom.We theoretically propose and demonstrate numerically and experimentally the broadband arbitrary ultrasound focusing in 3 D space.The axial and off-axis ultrasound focusing with the subwavelength resolution(FWHM<0.58λ)are achieved by the spatially sparse and compact metalens within one-octave bandwidth.With advantages of 3 D freewheeling focusing,subwavelength resolution,spatial sparsity,geometric simplicity,and broadband,the sparse metalens would offer more initiatives to advanced researches in ultrasound focusing and empower applications such as precise biomedical imaging and therapy,nondestructive evaluation,integrated and multiplexed ultrasound devices. | Xue Jiang JiaJie He ChuanXin Zhang HuaLiang Zhao WeiQi Wang DeAn Ta Cheng-Wei Qiu | 2022 | Science China(Physics,Mechanics & Astronomy)2022，65，2： | 1 |
| 7 | Correlations between signal spectrum of ultrasonic backscatter andcancellous bone mi- crostructure显示文摘 | TA Dean HUANG Kai WANG Weiqi | 2009 | Ultrasonics Symposium (IUS)2009，9，： | 1 |
| 8 | Outcomes of static and dynamic facial nerve repair in head and neck cancer显示文摘 | Iseli TA Harris G Dean NR | | 0，，3： | 1 |
| 9 | A review of spinning, shear forming and flow forming process显示文摘 | Wong C C Dean TA Lin J | 2003 | International Journal of Machine Tools & Manufacture2003，43，14： | 1 |
| 10 | A study ofsurface topography, friction and lubricants in metalforming 显示文摘 | HuZM Dean TA | 2000 | International Journal of Machine Tools & Manufacture2000，40，： | 1 |
| 11 | The phytoestrogen genistein produces acute nitric oxide-dependent dilation of human forearm vascu lature with similar potency to 17-β estradiol显示文摘 | Walker HA Dean TS Sand ers TA | 2001 | Circulation2001，103，2： | 1 |
| 12 | Efficacy and effectiveness of an rVSV-vectored vaccine expressing Ebola surface glycoprotein:interim results from the Guinea ring vaccination cluster-randomised trial显示文摘 | Henao-Restrepo A M Longini I M Egger M Dean N E Edmunds W J Camacho A Carroll M W Doumbia M Draguez B Duraffour S Enwere G Grais R Gunther S Hossmann S KondéM K Kone S Kuisma E Levine M M Mandal S Norheim G Riveros X Soumah A Trelle S Vicari A S Watson C H Kéta S Kieny M P Rttingen J A | 2015 | Lancet2015，，9996： | 1 |
| 13 | Semi-automated fluorogenic PCR assays(TagMan)for rapid detection of Escherichia coli 0157:H7 and other shiga toxigenic Ecoli显示文摘 | Dean Nystrom EA Casey TA | 1999 | Mol Cell Probes1999，13，4： | 1 |
| 14 | The phytoestrogen genistein produces acute nitric oxide-dependent dilation of human forearm vasculature with similar potency to 17beta-estradiol显示文摘 | Walker HA Dean TS Sanders TA | 2001 | Circulation2001，103，2： | 1 |
| 15 | Dispersion of guided waves in viscous liquid-filled pipes显示文摘 | TA Dean WANG Weiqi WANG Yuanyuan | 2008 | Insight2008，50，1： | 1 |
| 16 | Identification and analysis of muitimode guided waves in tibia cortical bone显示文摘 | TA Dean HUANG Kal WANG Weiqi | 2006 | Ultrasonics2006，44，： | 1 |
| 17 | Simplified inverse filter tracking algorithm for estimating the mean trabecular bone spacing 显示文摘 | Huang Kai Ta Dean Wang Weiqi | 2008 | IEEE Trans UFFC2008，55，7： | 1 |
| 18 | Measurement of the dispersion and attenuation of cylindrical ultrasonic guided waves in long cortical bone 显示文摘 | Ta Dean Wang Weiqi Wang Yuanyuan | 2009 | Ultrasound in Med & Biol2009，38，4： | 1 |
| 19 | Identification and analysis of muhimode guided waves in tibia cortical bone 显示文摘 | Ta Dean Huang Kai Wang Weiqi | 2006 | Ultrasonics2006，44，： | 1 |
| 20 | A review of spinning,shear form- ing and flow forming processes显示文摘 | Wong C C Dean TA Lin J | 2003 | International Journal of Ma- chine Tools & Manufacture2003，43，： | 1 |
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