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| 1 | 治疗肺动脉高压药物赛乐西帕显示文摘1研制背景花生四烯酸(AA)代谢产物中的一个重要成分是前列环素(1,PGl2),主要在血管内皮细胞中生成。PGI:具有多种生理功能,可强效地舒张血管,抑制血小板聚集,还抑制血管平滑肌细胞分化、增殖和迁移。PGl2的这些功能是通过与血管平滑肌细胞、血小板或其他细胞膜上的PGl2受体结合而产生的。PGl2途径的下调可引起一些血管性疾病,例如肺动脉高压。 | 郭宗儒 asaki t kuwano k morrison k | 2018 | 药学学报2018，53，12： | 3 |
| 2 | A variational approach to reconstructing images corrupted by poisson noise 显示文摘 | Asaki T Chartrand R Le T | 2007 | Journal of Mathematical Imaging and Vision2007，27，3： | 1 |
| 3 | A variational approach to constructing images corrupted by PoJsson noise 显示文摘 | T LE R CHARTRAND T ASAKI | 2007 | Journal of Mathematical Imaging and Vision2007，27，3： | 1 |
| 4 | A variational approach to reconstructing images corrupted by Poisson noise显示文摘 | Le T Chartrand R Asaki T J | 2007 | Journal of Mathematical Imaging and Vision2007，27，3： | 1 |
| 5 | Adenovirus expressing mu- tant P27kip1 enhanced apoptosis against cholangiocarcinoma than adenovirus-P27kip1 wild type显示文摘 | Asaki T Katayose Y Suzuki M | 2004 | Hepatogastroenterology2004，51，55： | 1 |
| 6 | A variational approach to recontructing images corrupted by Poisson noise显示文摘 | Le T Chartrand R and Asaki T J | 2007 | Journal of Mathematical Imaging and Vision2007，27，3： | 1 |
| 7 | TRAF6 deficiency results in osteopetrosis and defective interleukin-1,CD40,and LPS signaling显示文摘 | Lomaga MA Yeh WC Sarosi I Duncan GS Furlonger C Ho A Morony S Capparelli C Van G Kaufman S van der Heiden A Itie A Wakeham A Khoo W S asaki T Cao Z P enninger J M Paige CJ Lacey DL Dunstan CR Boyle WJ Goeddel DV Mak TW | | 0，，： | 1 |
| 8 | Oxidation of dense iron sulfide显示文摘 | ASAKI Z MATSUMOTO K TANABE T | 1983 | Metallurgical Transactions B1983，14，： | 1 |
| 9 | Utilization of bamboo charcoal in spinach cultivation 显示文摘 | Asaki T | 2006 | Agriculture and Horticulture2006，81，12： | 1 |
| 10 | A Hybrid Active Filter for Damping of Harmonic Resonance in Industrial Power Systems 显示文摘 | Fu Jita H Yam Asaki T Akagi H | 2000 | IEEE Trans Power Electron2000，15，2： | 1 |
| 11 | Utilization of bamboo charcoal in spinach cultivation显示文摘 | Asaki T | 2006 | Agriculture and Horticulture2006，81，12： | 1 |
| 12 | Matrilysin (MMP-7) as a ignificant determinant of malignant potential of early invasive colorectal carcinomas 显示文摘 | Asaki T Matsuoka H Sugiyama M et cd | 2001 | British Journal of Cancer2001，84，10： | 1 |
| 13 | Exogenous expression of claudin-5 induces barrier proper- ties in cultured rat brain capillary endothelial cells 显示文摘 | Ohtsuki S Sato S Yamaguchi H Kamoi M Asashima T Ter- asaki T | 2007 | J Cell Physiol2007，210，1： | 1 |
| 14 | 2-[4-[(5,6-diphenylpyrazin-2-yl) (isopropyl) amino]butoxy]-N-(methylsulfonyl) acetamide (NS-304),an orally available and long-acting prostacyclin receptor agonist prodrug显示文摘 | Kuwano K Hashino A Asaki T | | 0，，03： | 1 |
| 15 | Selexipag : an oral and selective IP prostacyclin receptor agonist for the treat- ment of pulmonary arterial hypertension 显示文摘 | ASAKI T KUWANO K MORRISON K | 2015 | J Med Chem2015，58，18： | 1 |
| 16 | Elevation of plasma retinol - binding protein 4 and reduction of plasma adiponeetin in subjects with cerebral infarction 显示文摘 | asaki M Otani T Kawakami M | 2010 | Metabolism2010，59，4： | 1 |
| 17 | Improved durability of iridium oxide coated titanium anode with interlayers for oxygen evolution at high current densities 显示文摘 | KAMEGAYA Y SASAKI K OGURI M ASAKI T KOBAYASHI H MITAMURA T | 1995 | Electrochim Acta1995，40，： | 1 |
| 18 | Utilization of bamboo charcoal in spinach cultivation显示文摘 | ASAKI T | 2006 | Agriculture and Horticulture2006，81，12： | 1 |
| 19 | Neudesin,an extracellular heine-binding protein,suppresses adipogenesis in 3T3-L1 cells via the MAPK cascade显示文摘 | Kimura I Konishi M Asaki T | 2009 | Biochem Biophys Res Commun2009，381，1： | 1 |
| 20 | Utilization of bamboo charcoal in spinach cultiva-tion显示文摘 | Asaki T | | 0，，12： | 1 |
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