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| 1 | Current surgical management of pancreatic endocrine tumor liver metastases显示文摘BACKGROUND: The management of metastatic disease in pancreatic endocrine tumors (PETs) demands a multidisciplinary approach and the cooperation of several medical specialties. The role of surgery is critical, even when a radical excision cannot always be achieved. DATA SOURCES: A PubMed search of relevant articles published up to February 2011 was performed to identify current information about PET liver metastases regarding diagnosis and management, with an emphasis on surgery. RESULTS: The early diagnosis of metastases and their accurate localization, most commonly in the liver, is very important. Surgical options include radical excision, and palliative excision to relieve symptoms in case of failure of medical treatment. The goal of the radical excision is to remove the primary tumor bulk and all liver metastases at the same time, but unfortunately it is not feasible in most cases. Palliative excisions include aggressive tumor debulking surgeries in well-differentiated carcinomas, trying to remove at least 90% of the tumor mass, combined with other additional destructive techniques such as hepatic artery embolization or chemoembolization to treat metastases or chemoembolization to relieve symptoms in cases of rapidly growing tumors. The combination of chemoembolization and systemic chemotherapy results in better response and survival rates. Other local destructive techniques include ethanol injection, cryotherapy and radiofrequency ablation. CONCLUSION: It seems that the current management of PETs can achieve important improvements, even in advanced cases. | Theodoros E Pavlidis Kyriakos Psarras Nikolaos G Symeonidis Efstathios T Pavlidis Athanasios K Sakantamis | 2011 | Hepatobiliary & Pancreatic Diseases International2011，10，3： | 5 |
| 2 | Ankle-brachial index:a surrogate marker of microvaseular complications in type 2 diabetic mellitus显示文摘 | Papanas N Symeonidis G Mavridis G | 2007 | International Angiology2007，26，3： | 1 |
| 3 | Impairment of erythrocyte vis- coelasticity is correlated with levels of glycosylated haemoglobin in diabetic patients 显示文摘 | Symeonidis A Athanassiou G Psiroyarmis A | 2001 | Clin Lab Haematol2001，23，2： | 1 |
| 4 | Downstream merger and welfare in a bilateral oligopoly 显示文摘 | Symeonidis G | 2010 | International Journal of Industrial Organization1 /2010，28，3： | 1 |
| 5 | Mean platelet volume in patients with type 2 diabetes mellitus 显示文摘 | Papanas N Symeonidis G Maltezos E | 2004 | Platelets2004，15，： | 1 |
| 6 | Comparing cournot and Bertrand equilibrium in a differentiated duopoly with product R&D 显示文摘 | SYMEONIDIS G | 2003 | International Journal of Industrial O organization2003，，21： | 1 |
| 7 | Comparing cournot and bertrand equilibrium in a differentiated duopoly with product R&D显示文摘 | Symeonidis G | 2003 | International Journal of Industrial Organization2003，，21： | 1 |
| 8 | Quality heterogeneity and welfare显示文摘 | Symeonidis G | | 0，，78： | 1 |
| 9 | Acute appendicitis in a duplicated appendix显示文摘 | Christodoulidis G Symeonidis D Spyridakis M | 2012 | Int J Surg Case Rep2012，3，： | 1 |
| 10 | 显示文摘 | Yiqing D Symeonidis V Karniadakis G E | 2002 | J Fluid Mech2002，457，： | 1 |
| 11 | Mean platelet volume in patients with type 2 diabetes mellitus显示文摘 | Papanas N Symeonidis G Maltezos E | 2004 | Platelets2004，15，8： | 1 |
| 12 | Comparing Cournot and Bertrand equi-libria in a differentiated duopoly with product R&D显示文摘 | SYMEONIDIS G | 2003 | International Journal of Industrial Organization2003，21，1： | 1 |
| 13 | Comparing Coumot and Bertrand equilibrium in a differentiated duopoly with R&D 显示文摘 | Symeonidis G | 2003 | International Journal of Industrial Organization2003，，21： | 1 |
| 14 | Gravity of aortic arch calcification as evaluated in adult Greek patients显示文摘 | Symeonidis G Papanas N Giannakis I | 2002 | Int Angiol2002，21，3： | 1 |
| 15 | Open inguinal hernia repair with the use of a polyglcolic acid - trimethylene carbonate ab- serbable mesh:a pilot study显示文摘 | Efthimiou M Symeonidis D Koukoulis G | 2011 | Hernia2011，15，2： | 1 |
| 16 | Comparing Cournot and Bertrand equilibrium in a differentiated duopoly with R&D显示文摘 | | 2003 | International Journal of Industrial Organization2003，，21： | 1 |
| 17 | Long-term resultsafter laparoscopic transabdominal preperitoneal ( TAPP) inguinalhernia repair under spinal anesthesia 显示文摘 | Tzovaras G Symeonidis D Koukoulis G | 2012 | Hernia2012，16，6： | 1 |
| 18 | Dissi-pative particle dynamics simulations of polymer chains: Scalinglaws and shearing response compared to dna experiments 显示文摘 | SYMEONIDIS V EM KARNIADAKIS G CASWELL B | 2005 | Phys Rev Lett2005，95，76： | 1 |
| 19 | Open inguinal hernia repair with the use of a polyglycolic acid-trimethylene car- bonate absorbable mesh: a pilot study 显示文摘 | Efthimiou M Symeonidis D Koukoulis G | 2011 | Hernia2011，15，2： | 1 |
| 20 | Downstream Merger and Welfare in a Bilateral Oligopoly显示文摘 | Symeonidis G | 2010 | International Journal of Industrial Organi- zation2010，28，3： | 1 |
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