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| 1 | Health-related quality of life, work productivity, and health care resource utilization of subjects with irritable bowel syndrome: Baseline results from logic (longitudinal outcomes study of gastrointestinal symptoms in Canada), a naturalistic study显示文摘 | Pierre Paré James Gray Sy Lam Robert Balshaw Shideh Khorasheh Martin Barbeau Suzanne Kelly Christopher R. McBurney | 2006 | Clinical Therapeutics2006，，10： | 2 |
| 2 | Teaching Young Children: Perceived Satisfaction and Stress显示文摘 | Suzanne Edmonds Peter Blatch Ford Clare Martin | 2001 | Educational Research2001，143，2： | 1 |
| 3 | Validation and Implementation of Targeted Capture and Sequencing for the Detection of Actionable Mutation, Copy Number Variation, and Gene Rearrangement in Clinical Cancer Specimens显示文摘 | Colin C. Pritchard Stephen J. Salipante Karen Koehler Christina Smith Sheena Scroggins Brent Wood David Wu Ming K. Lee Suzanne Dintzis Andrew Adey Yajuan Liu Keith D. Eaton Renato Martins Kari Stricker Kim A. Margolin Noah Hoffman Jane E. Churpek Jonathan | 2014 | The Journal of Molecular Diagnostics2014，，1： | 1 |
| 4 | Hepatectomy is Superior to Thermal Ablation for Patients with a Solitary Colorectal Liver Metastasis显示文摘 | Suzanne Claire Schiffman Matthew Bower Russell E. Brown Robert C. G. Martin Kelly M. McMasters Charles R. Scoggins | 2010 | Journal of Gastrointestinal Surgery2010，，12： | 1 |
| 5 | Cluster of Solitons in Weakly Correlated Wave Fronts显示文摘 | ZHIGANG CHEN SUZANNE SEARS M HECTOR MARTIN | 2002 | Proc Natl Acad Sci2002，99，8： | 1 |
| 6 | Macromolecular Transport in Jejunal Mucosa of Children with Severe Malnutrition: A Quantitative Study显示文摘 | Martine Heyman Ghazalia Boudraa Suzanne Sarrut Maud Giraud Lynleigh Evans Mahmoud Touhami Jehan-Fran?ois Desjeux | 1984 | Journal of Pediatric Gastroenterology and Nutrition1984，，3： | 1 |
| 7 | Accuracy of invasive and noninvasive tests to diagnose Helicobacter pylori infection显示文摘 | Alan F. Cutler Suzanne Havstad Chen K. Ma Martin J. Blaser Guillermo I. Perez-Perez Timothy T. Schubert | 1995 | Gastroenterology1995，，1： | 1 |
| 8 | Theobroma cacao improves bone growth by modulating defective ciliogenesis in a mouse model of achondroplasia显示文摘A gain-of-function mutation in the fibroblast growth factor receptor 3 gene(FGFR3)results in achondroplasia(ACH),the most frequent form of dwarfism.Constitutive activation of FGFR3 impairs bone formation and elongation and many signal transduction pathways.Identification of new and relevant compounds targeting the FGFR3 signaling pathway is of broad importance for the treatment of ACH,and natural plant compounds are prime drug candidate sources.Here,we found that the phenolic compound(-)-epicatechin,isolated from Theobroma cacao,effectively inhibited FGFR3’s downstream signaling pathways.Transcriptomic analysis in an Fgfr3 mouse model showed that ciliary mRNA expression was modified and influenced significantly by the Indian hedgehog and PKA pathways.(-)-Epicatechin is able to rescue mRNA expression impairments that control both the structural organization of the primary cilium and ciliogenesis-related genes.In femurs isolated from a mouse model(Fgfr3^(Y367C/+))of ACH,we showed that(-)-epicatechin eliminated bone growth impairment during 6 days of ex vivo culture.In vivo,we confirmed that daily subcutaneous injections of(-)-epicatechin to Fgfr3^(Y367C/+) mice increased bone elongation and rescued the primary cilium defects observed in chondrocytes.This modification to the primary cilia promoted the typical columnar arrangement of flat proliferative chondrocytes and thus enhanced bone elongation.The results of the present proof-of-principle study support(-)-epicatechin as a potential drug for the treatment of ACH. | Ludovic Martin Nabil Kaci Catherine Benoist-Lasselin Marine Mondoloni Suzanne Decaudaveine Valentin Estibals Maxence Cornille Léa Loisay Justine Flipo Benoît Demuynck Maria de la Luz Cádiz-Gurrea Florent Barbault Salvador Fernández-Arroyo Laurent Schibler Antonio Segura-Carretero Emilie Dambroise Laurence Legeai-Mallet | 2022 | Bone Research2022，10，1： | 1 |
| 9 | Intramyocardial Injection of Autologous Bone Marrow-Derived Ex Vivo Expanded Mesenchymal Stem Cells in Acute Myocardial Infarction Patients is Feasible and Safe up to 5 Years of Follow-up显示文摘 | Sander F. Rodrigo Jan Ramshorst Georgette E. Hoogslag Helèn Boden Matthijs A. Velders Suzanne C. Cannegieter Helene Roelofs Imad Younis Petra Dibbets-Schneider Willem E. Fibbe Jaap Jan Zwaginga Jeroen J. Bax Martin J. Schalij Saskia L. Beeres Douwe E. Ats | 2013 | Journal of Cardiovascular Translational Research2013，，5： | 1 |
| 10 | Su1010 International Variation in Medication Prescription Rates in Elderly Patients With Inflammatory Bowel Disease显示文摘 | Eric I. Benchimol Suzanne Cook Rune Erichsen Charles N. Bernstein Jenna Wong Charlotte F. Carroll Trine Froslev Christopher F. Martin Michael Kappelman | 2012 | Gastroenterology2012，，5： | 1 |
| 11 | Participants' perspective on main- taining behaviour change: a qualitative study within the European diabetes prevention study 显示文摘 | Linda P Suzanne M Martin W | 2008 | BMC Public Health2008，8，7： | 1 |
| 12 | Efficacy and safety of sunitinib in patients with advanced gastrointestinal stromal tumour after failure of imatinib: a randomised controlled trial显示文摘 | George D Demetri Allan T van Oosterom Christopher R Garrett Martin E Blackstein Manisha H Shah Jaap Verweij Grant McArthur Ian R Judson Michael C Heinrich Jeffrey A Morgan Jayesh Desai Christopher D Fletcher Suzanne George Carlo L Bello Xin Huang Charles | 2006 | The Lancet2006，，9544： | 1 |
| 13 | Accreditation and quality assurance for Radiation Therapy Oncology Group: Multicenter clinical trials using Stereotactic Body Radiation Therapy in lung cancer显示文摘 | Robert Timmerman James Galvin Jeff Michalski William Straube Geoffrey Ibbott Elizabeth Martin Ramzi Abdulrahman Suzanne Swann Jack Fowler Hak Choy | 2006 | Acta Oncologica2006，，7： | 1 |
| 14 | Combined NGS Approaches Identify Mutations in the Intraflagellar Transport Gene IFT140 in Skeletal Ciliopathies with Early Progressive Kidney Disease显示文摘 | Miriam Schmidts Valeska Frank Tobias Eisenberger Saeed al Turki Albane A. Bizet Dinu Antony Suzanne Rix Christian Decker Nadine Bachmann Martin Bald Tobias Vinke Burkhard Toenshoff Natalia Di Donato Theresa Neuhann Jane L. Hartley Eamonn R. Maher Radovan | 2013 | Human Mutation2013，，5： | 1 |
| 15 | Is cardiovascular evaluation necessary prior to and during beta-blocker therapy for infantile hemangiomas?显示文摘 | Martine F. Raphael Corstiaan C. Breugem Florine AE. Vlasveld Marlies de Graaf Martijn G. Slieker Suzanne GMA. Pasmans Johannes MPJ. Breur | 2014 | Journal of the American Academy of Dermatology2014，，： | 1 |
| 16 | Efficacy and safety of sunitinib in patients with advanced gastrointestinal stromal tumour after failure of imatinib: a randomised controlled trial显示文摘 | George D Demetri Allan T van Oosterom Christopher R Garrett Martin E Blackstein Manisha H Shah Jaap Verweij Grant McArthur Ian R Judson Michael C Heinrich Jeffrey A Morgan Jayesh Desai Christopher D Fletcher Suzanne George Carlo L Bello Xin Huang Charles | 2006 | The Lancet . 2006 (9544)2006，，9544： | 1 |
| 17 | Impact of Renal Denervation on 24-hour Ambulatory Blood Pressure: Results from SYMPLICITY HTN-3显示文摘 | George L. Bakris Raymond R. Townsend Minglei Liu Sidney A. Cohen Ralph D’Agostino John M. Flack David E. Kandzari Barry T. Katzen Martin B. Leon Laura Mauri Manuela Negoita William W. O’Neill Suzanne Oparil Krishna Rocha-Singh Deepak L. Bhatt | 2014 | Journal of the American College of Cardiology2014，，： | 1 |
| 18 | Global and regional burden of first-ever ischaemic and haemorrhagic stroke during 1990–2010: findings from the Global Burden of Disease Study 2010显示文摘 | Rita V Krishnamurthi Valery L Feigin Mohammad H Forouzanfar George A Mensah Myles Connor Derrick A Bennett Andrew E Moran Ralph L Sacco Laurie M Anderson Thomas Truelsen Martin O’Donnell Narayanaswamy Venketasubramanian Suzanne Barker-Collo Carlene M M La | 2013 | The Lancet Global Health2013，，5： | 1 |
| 19 | Usefulness of Intra-Aortic Balloon Pump Counterpulsation in Patients With Cardiogenic Shock from Acute Myocardial Infarction显示文摘 | Jin M. Cheng Suzanne D.A. Valk Corstiaan A. den Uil Martin van der Ent Wim K. Lagrand Meike van de Sande Ron T. van Domburg Maarten L. Simoons | 2009 | The American Journal of Cardiology2009，，3： | 1 |
| 20 | Efficacy and safety of sunitinib in patients with advanced gastrointestinal stromal tumour after failure of imatinib: a randomised controlled trial显示文摘 | George D Demetri Allan T van Oosterom Christopher R Garrett Martin E Blackstein Manisha H Shah Jaap Verweij Grant McArthur Ian R Judson Michael C Heinrich Jeffrey A Morgan Jayesh Desai Christopher D Fletcher Suzanne George Carlo L Bello Xin Huang Charles | 2006 | The Lancet2006，，9544： | 1 |
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