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| 1 | A Modified Plate Assay for Rapid Screening of Potassium-Solubilizing Bacteria显示文摘The utility of microorganisms for solubilizing the unavailable forms of potassium(K) from soil has led to renewed interest in fabrication of rapid and sensitive plate assays for their isolation and screening. The present study developed a modified plate assay and compared it with previously reported methods for the isolation and screening of K-solubilizing bacteria. The newly developed plate assay is based on improved visualization of halo zone formation around the colonies on agar plates, through inclusion of an acid-base indicator dye, bromothymol blue(BTB), to modify the previously reported Aleksandrov medium. The halo zone exhibited a significant correlation(R = 0.939) with K released in liquid medium. The visualization of potential K solubilizers was improved using this method, which would help in detection of weak/non-acid producers based on secretion of organic acids in the medium. Organic acids in plate diffuse radially and form halo zones in response to reaction with the acid-base indicator dye BTB. Furthermore, K solubilization on plates with this method can be observed within 48–72 h, against the incubation time of 4–5 d needed in the earlier method. Therefore, the newly developed protocol for the plate assay was time saving, more sensitive, and beneficial in comparison to the previously reported Aleksandrov plate assay. | Mahendra Vikram Singh RAJAWAT Surender SINGH Satya Prakash TYAGI Anil Kumar SAXENA | 2016 | Pedosphere2016，26，5： | 6 |
| 2 | Evidence of Grapevine leafroll associated virus-1–3, Grapevine fleck virus and Grapevine virus B Occurring in Himachal Pradesh, India显示文摘 | Surender Kumar Lakhmir Singh Luca Ferretti Marina Barba Aijaz A. Zaidi Vipin Hallan | 2013 | Indian Journal of Virology2013，，1： | 1 |
| 3 | Simplex and duplex PCR assays for species specific identification of cattle and buffalo milk and cheese显示文摘 | Sachinandan De Biswajit Brahma Shamik Polley Ayan Mukherjee Deepak Banerjee Moloya Gohaina Karan Pratap Singh Rameswar Singh Tirtha Kumar Datta Surender Lal Goswami | 2010 | Food Control2010，，5： | 1 |
| 4 | Helicobacter pylori Induces Apoptosis of T- and B-Cell Lines and Translocates Mitochondrial Apoptosis-Inducing Factor to Nucleus显示文摘 | Manisha Singh Kashi N. Prasad Ashish Saxena Surender K. Yachha | 2006 | Current Microbiology2006，，4： | 1 |
| 5 | Effects of transgenic Bt cotton on soil fertility and biology under field conditions in subtropical inceptisol显示文摘 | Raman Jeet Singh I. P. S. Ahlawat Surender Singh | 2013 | Environmental Monitoring and Assessment2013，，1： | 1 |
| 6 | Targeting MUC1-C suppresses BCL2A1 in triple-negativebreast cancer显示文摘B-cell lymphoma 2-related protein A1(BCL2A1)is a member of the BCL-2 family of anti-apoptotic proteins that confers resistance to treatment with anti-cancer drugs;however,there are presently no agents that target BCL2A1.The MUC1-C oncoprotein is aberrantly expressed in triple-negative breast cancer(TNBC)cells,induces the epithelial–mesenchymal transition(EMT)and promotes anti-cancer drug resistance.The present study demonstrates that targeting MUC1-C genetically and pharmacologically in TNBC cells results in the downregulation of BCL2A1 expression.The results show that MUC1-C activates the BCL2A1 gene by an NF-κB p65-mediated mechanism,linking this pathway with the induction of EMT.The MCL-1 anti-apoptotic protein is also of importance for the survival of TNBC cells and is an attractive target for drug development.We found that inhibiting MCL-1 with the highly specific MS1 peptide results in the activation of the MUC1-C→NF-κB→BCL2A1 pathway.In addition,selection of TNBC cells for resistance to ABT-737,which inhibits BCL-2,BCL-xL and BCL-W but not MCL-1 or BCL2A1,is associated with the upregulation of MUC1-C and BCL2A1 expression.Targeting MUC1-C in ABT-737-resistant TNBC cells suppresses BCL2A1 and induces death,which is of potential therapeutic importance.These findings indicate that MUC1-C is a target for the treatment of TNBCs unresponsive to agents that inhibit anti-apoptotic members of the BCL-2 family. | Masayuki Hiraki Takahiro Maeda Neha Mehrotra Caining Jin Maroof Alam Audrey Bouillez Tsuyoshi Hata Ashujit Tagde Amy Keating Surender Kharbanda Harpal Singh Donald Kufe | 2018 | Signal Transduction and Targeted Therapy2018，3，1： | 1 |
| 7 | Evaluation of immunomodulatory potential of Ocimum sanctum seed oil and its possible mechanism of action显示文摘 | P.K Mediratta K.K Sharma Surender Singh | 2002 | Journal of Ethnopharmacology2002，，1： | 1 |
| 8 | Effect of Ocimum sanctum fixed oil on blood pressure, blood clotting time and pentobarbitone-induced sleeping time显示文摘 | Surender Singh H.M.S Rehan D.K Majumdar | 2001 | Journal of Ethnopharmacology2001，，2： | 1 |
| 9 | Hydroxamates of para-aminoben- zoic acid as selective inhibitors of HDAC8显示文摘 | Kulandaivelu Umasankar Chilakamari Laxmi Manasa Jadav Surender Singh | 2014 | Bioorganic Chemistry2014，57，： | 1 |
| 10 | Evaluation of anti-inflammatory potential of fixed oil of Ocimum sanctum (Holybasil) and its possible mechanism of action显示文摘 | Surender Singh D.K. Majumdar H.M.S. Rehan | 1996 | Journal of Ethnopharmacology1996，，1： | 1 |
| 11 | Anti-inflammatory and Antipyretic Activities of Ocimum Sanctum Fixed Oil显示文摘 | Surender Singh D. K. Majumdar | 1995 | Pharmaceutical Biology1995，，4： | 1 |
| 12 | Analgesic Activity of Ocimum sanctum and its Possible Mechanism of Action显示文摘 | Surender Singh D. K. Majumdar | 1995 | Pharmaceutical Biology1995，，3： | 1 |
| 13 | Rare double fracture-dislocation of the thumb: a case report and review of the literature显示文摘metacarpophalangeal (MCP ) 的关节和脱臼连接的姆指 carpometacarpal (CMC ) 的同时的破裂 / 脱臼被看作一个稀罕损害模式。我们报导与底的 extraarticular 骨折联系的姆指联合的 MCP 的背面的脱臼的一个不平常的案例第一在一个 28 岁的人掌部。MCP 关节的脱臼在一个外部中心在起始的表示期间被错过了。病人与 1.25 使一个平静恢复追随者成为了开的减小和固定;与尺骨的并行的系带的修理一起的 MCP 关节的公里 Kirschner 电线。这个损害模式以前没在英语语言的基于的医药文学就我们的知识而言被报导。 | Davinder Singh Loveneesh G Krishna Sunil Dhaka Surender Kumar Sumit Arora | 2013 | Chinese Journal of Traumatology2013，16，4： | 1 |
| 14 | Establishment and characterization of a buffalo (bubalus bubalis) mammary epithe- lial cell line 显示文摘 | Vijay Anand Nilambra Dogra Surender Singh | 2012 | PLOS ONE2012，7，7： | 1 |
| 15 | Influence of Endosulfan on Microbial Biomass and Soil Enzymatic Activities of a Tropical Alfisol显示文摘 | S. Surya Kalyani Jitender Sharma Prem Dureja Surender Singh Lata | 2010 | Bulletin of Environmental Contamination and Toxicology2010，，3： | 1 |
| 16 | Indian task force for celiac disease:Current status显示文摘There are limited data on celiac disease(CD) from India.The limited knowledge about CD in India might be attributed to several factors.The fi rst meeting of the Indian Task Force for Celiac Disease was held in the Asian Institute of Gastroenterology,Hyderabad,India in December 2008.The objectives of the meeting were to focus research on prevalence of CD in the wheat-eating Northern vs the rice-eating Southern Indian population,low-budget serological assays to study the underprivileged population,to involve other medical subspecialties in CD,to suggest proper legislation regarding wheat food labeling,and to organize affordable food substitutes for patients with celiac disease. | Rajesh Gupta Duvvuru Nageshwar Reddy Govind K Makharia Ajit Sood Balakrishnan S Ramakrishna Surender Kumar Yachha Babu Ram Thapa Rupa Banerjee Sekaran Anuradha Usha Dutta Amarender Singh Puri Ajay Kumar Jain Chris JJ Mulder Ajay Kumar Sesikeran Boindala | 2009 | World Journal of Gastroenterology2009，15，48： | 1 |
| 17 | En- ergy Optimization in ZigBee Using Prediction based Shortest Path Routing Algorithm 显示文摘 | Dhirendra Pratap Singh Yash Agrawal Surender Kumar Soni | 2012 | Emerging Trends and Applications in Com- puter Scinece (NCETACS)2012，97，81： | 1 |
| 18 | Quantifying Design Parameters of Symbology Page for Automotive Head up Display显示文摘 | Gupta Sharad Karar Vinod Saini Surender Singh Jaggi Neena Bajpai Phun Phun | 2011 | Computer Technology and Application2011，2，8： | 0 |
| 19 | Ethnopharmacological,phytochemical and clinical studies on Fenugreek(Trigonella foenum-graecum L.)显示文摘Trigonella foenum-graecum(fenugreek)belonging to the family Fabaceae,is widely used for both culinary as well as clinical purposes since antiquity.Folkloric medicines across globe particularly use this plant for boosting immunity and combating digestive and reproductive impairments.The plant is rich reservoir of different phytoconstituents attributed to their diverse pharmacological effects.Therefore,the present article is planned on its ethnomedicinal uses,botanical description,phytochemistry,pharmacology,toxicology,clinical efficacy,mechanism of action and nanoparticle synthesis.In all pharmacological studies,the dose,major bioactive,type of extract and possible outcomes is also discussed,to establish its specific role against a particular ailment.It was hypothesized that the nanoparticle synthesis will lead to the enhanced pharmacology.Results showed that ethnomedicinal data well supports the different pharmacological aspects of Trigonella formulations in different countries.Trigonelline(phytoestrogen)renders most of therapeutic potential of Trigonella.The reported therapeutics can also be accounted as the synergistic pharmacology of different bioactives.Nanoparticle synthesis significantly improves its pharmacological efficacy.Clinical studies well validated its antidiabetic and reproductive health improving efficacies.Though no serious toxic effects were observed with the use of this plant but further well-designed placebo trials are still needed to demonstrate its full therapeutic potential. | Neetu Singh Surender Singh Yadav Sanjiv Kumar Balasubramaniam Narashiman | 2022 | Food Bioscience2022，46，2： | 0 |
| 20 | sp^(2)碳用于3D打印技术综述:材料、性能和应用显示文摘3D打印可以改变现有的生产方法,是第四次工程革命中的一项现代技术。它从成型原理上提出了分层制造、逐层叠加成型的新颖生产方法,从根本上简化了制造工艺,实现了大规模定制生产。然而,这一新技术仍存在许多问题。除了纯石墨烯外,sp^(2)碳具有好的亲水性,3D打印难度较小。sp^(2)碳还可在3D打印中的各种阶段应用。纯石墨烯的疏水性使其难以在水系介质中打印和加工。毛细管油墨的发展使得纯石墨烯的3D打印成为可能。本文综述了sp^(2)碳的3D打印技术的最新进展。首先简要概述了3D打印技术,随后概述了sp^(2)碳的3D打印及其在各种方面的应用。最后,讨论了这一新领域的发展前景和机遇。 | Satendra Kumar Manoj Goswami Netrapal Singh Sathish Natarajan Surender Kumar | 2022 | 新型炭材料(中英文)2022，37，6： | 0 |
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