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| 1 | Fluorodeoxyglucose positron emission tomography/computed tomography and magnetic resonance imaging of uterine leiomyosarcomas: 2 cases report显示文摘子宫的 leiomyosarcoma 是光滑的肌肉起源的一个不平常的恶意的瘤并且与差的预后被联系。我们报导那与肺的 metastases.2-deoxy-2-(18F ) 介绍了的子宫的 leiomyosarcoma 的二个案例 fluorodeoxyglucose (FDG ) 正电子排放断层摄影术(宠物)/computed 断层摄影术(CT ) 被执行识别主要的癌并且发现焦点位于子宫。后续磁性的回声成像(MRI ) 证实诊断是子宫的 leiomyosarcoma。 | ZHANG Hui-juan ZHAN Feng-hua LI Yaojun SUN Hao-ran BAI Ren-ju GAO Shuo | 2011 | Chinese Medical Journal2011，，14： | 2 |
| 2 | Studies on natural STI zeolite : modification, structure,adsorption and catalysis 显示文摘 | LI Jun QIU Jin SUN Yaojun ei al | 2000 | Micropor Mesopor Mat2000，37，3： | 1 |
| 3 | Studies on natural STI zeolite:modification,structure,adsorption and catalysis显示文摘 | LI JUN QIU JIN SUN YAOJUN | 2000 | Microporous and Mesoporous Materials2000，37，3： | 1 |
| 4 | Studies on natural STI zeolite: modification, structure, adsorption and catalysis 显示文摘 | Li Jun Qiu Jin Sun Yaojun | 2000 | Microporous and Mesoporans Materials2000，37，： | 1 |
| 5 | Proteomics analysis of differentially expressed proteins in schistosomula and adult worms of Schistosoma japonicum显示文摘 | Yang Hong Anguo Sun Min Zhang Fei Gao Yanhui Han Zhiqiang Fu Yaojun Shi Jiaojiao Lin | 2012 | Acta Tropica2012，，： | 1 |
| 6 | Beauvericin counteracted multi-drug resistant Candida albicans by blocking ABC transporters显示文摘Multi-drug resistance of pathogenic microorganisms is becoming a serious threat,particularly to immunocompromised populations.The high mortality of systematic fungal infections necessitates novel antifungal drugs and therapies.Unfortunately,with traditional drug discovery approaches,only echinocandins was approved by FDA as a new class of antifungals in the past two decades.Drug efflux is one of the major contributors to multi-drug resistance,the modulator of drug efflux pumps is considered as one of the keys to conquer multi-drug resistance.In this study,we combined structure-based virtual screening and whole-cell based mechanism study,identified a natural product,beauvericin(BEA)as a drug efflux pump modulator,which can reverse the multi-drug resistant phenotype of Candida albicans by specifically blocking the ATP-binding cassette(ABC)transporters;meantime,BEA alone has fungicidal activity in vitro by elevating intracellular calcium and reactive oxygen species(ROS).It was further demonstrated by histopathological study that BEA synergizes with a sub-therapeutic dose of ketoconazole(KTC)and could cure the murine model of disseminated candidiasis.Toxicity evaluation of BEA,including acute toxicity test,Ames test,and hERG(human ether-a-go-go-related gene)test promised that BEA can be harnessed for treatment of candidiasis,especially the candidiasis caused by ABC overexpressed multi-drug resistant C.albicans. | Yaojun Tong Mei Liu Yu Zhang Xueting Liu Ren Huang Fuhang Song Huanqin Dai Biao Ren Nuo Sun Gang Pei Jiang Bian Xin-Ming Jia Guanghua Huang Xuyu Zhou Shaojie Li Buchang Zhang Takashi Fukuda Hiroshi Tomoda SatoshiOmura Richard DCannon Richard Calderone Lixin Zhang | 2016 | Synthetic and Systems Biotechnology2016，1，3： | 1 |
| 7 | Revolutionizing Antibody Discovery:An Innovative AI Model for Generating Robust Libraries显示文摘Background Artificial intelligence models of natural language are becoming increasingly adept at processing and‘understanding’language.They are widely used in applications such as automated speech recognition,translation,smart assistants,and text generation[1].Recently,language models have been applied to such problems as protein function prediction,protein evolution analysis,and protein design[2]. | Yaojun Wang Shiwei Sun | 2023 | Genomics, Proteomics & Bioinformatics2023，21，5： | 0 |
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