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| 1 | Deletion of the Initial 45 Residues of ARR18 Induces Cytokinin Response in Arabidopsis显示文摘植物荷尔蒙细胞激动素在植物生长和开发的各种各样的方面起重要作用。细胞激动素发信号被类似于细菌的二部件的系统的 multistep phosphorelay 调停。在发信号的细胞激动素的结束的 Type-B ARR 谎言,典型地调停产量反应。然而, type-B ARR 怎么响应细胞激动素被调整,仍然是不清楚的。典型 type-B ARR 包含一个 N 终端接收装置领域和一个 C 终端受动器领域。在这研究,我们由 overexpressing 执行了染色体野的比较分析七代表性的 type-B ARR 的完整的长度和 C 终端受动器领域。我们的结果显示了没有细胞激动素的增加,受动器领域引起短主要的根和短胚轴的 C 终端的那 overexpression,建议在受动器领域的活动的接收装置领域的禁止的角色是在 type-B ARR 的普通机制。调查接收装置领域怎么禁止受动器领域的活动,我们执行了删除分析。我们发现了那删除起始 ARR18 (从 N 终点的 45 残余) 的 45 残余由直接导致细胞激动素引起多种的生长缺点应答的基因。一起,我们的结果建议起始 45 残余为到在 ARR18 的受动器领域的接收装置领域的禁止的角色是批评的。 | Yan Liang Xingchun Wang Sulei Hong Yansha Li Jianru Zuo | 2012 | Journal of Genetics and Genomics2012，39，1： | 2 |
| 2 | Metal-support interaction controlled migration and coalescence of supported particles显示文摘The particle migration and coalescence(PMC) kinetics of a supported metal are the main deactivation mechanisms restricting the successful industrialization of nanoparticles, but the theoretical insights regarding these kinetics are lacking. One key issue is the lack of a physical model to predict the effects of metal-support interaction(MSI) on PMC kinetics. In this paper, we report a theoretical study of PMC kinetics and their dependence on MSI. A new particle diffusion model is proposed based on the surface premelting hypothesis that considers the contact angle of a hemispherical particle on the support. Enhanced MSI suppresses PMC by increasing the radius of curvature and the interfacial adhesion energy, even though the accompanying reduction in the geometry factor partially promotes PMC kinetics. The increased surface energy increases the chemical potential of the atoms in the particle, which is conducive to PMC; an increased surface energy also results in enhanced MSI, which suppresses PMC. The competition between these two contradictory effects leads to a critical contact angle where the surface energy has no influence on the diffusion and resulting PMC kinetics. The proposed diffusion theory mode lincluding the effects of the support and the corresponding kinetic simulations, shed light onto the support-dependence of PMC kinetics and provide a foundation for further optimization and design of supported particles with better stability. | HU SuLei LI Wei-Xue | 2019 | Science China(Technological Sciences)2019，62，5： | 1 |
| 3 | First-principles kinetics study of carbon monoxide promoted Ostwald ripening of Au particles on FeO/Pt(111)显示文摘The dynamic and kinetic evolution of supported metal particles in the presence of reactants is decisive in shaping the nature of the catalytic active sites and the deactivation process. Ostwald ripening of FeO/Pt(111) supported Au particles in the presence of carbon monoxide is addressed here by firstprinciples kinetics. It is found that CO stabilizes the ripening monomer(Au atom) by forming favorable Au carbonyls with lower total activation energy, and corresponding phase diagram at wide range of temperature and CO pressures is constructed. Evolution of particle number, dispersion and particle size distribution of supported Au particles are explored. Great influence of CO promotion on ripening kinetics is revealed and explored in details, and mbar range of CO can lower the onset temperature of ripening by a few hundred kelvins. The present work reveals the crucial role of the metal-reactant complexes formed under reaction conditions on ripening of metal catalysts. | Sulei Hu Runhai Ouyang Wei-Xue Li | 2019 | Journal of Energy Chemistry2019，28，3： | 1 |
| 4 | Osteopontin targeted theranostic nanoprobes for laser-induced synergistic regression of vulnerable atherosclerotic plaques显示文摘Vulnerable atherosclerotic plaque(VASPs)is the major pathological cause of acute cardiovascular event.Early detection and precise intervention of VASP hold great clinical significance,yet remain a major challenge.Photodynamic therapy(PDT)realizes potent ablation efficacy under precise manipulation of laser irradiation.In this study,we constructed theranostic nanoprobes(NPs),which could precisely regress VASPs through a cascade of synergistic events triggered by local irradiation of lasers under the guidance of fluorescence/MR imaging.The NPs were formulated from human serum albumin(HSA)conjugated with a high affinity-peptide targeting osteopontin(OPN)and encapsulated with photosensitizer IR780 and hypoxia-activatable tirapazamine(TPZ).After intravenous injection into atherosclerotic mice,the OPN-targeted NPs demonstrated high specific accumulation in VASPs due to the overexpression of OPN in activated foamy macrophages in the carotid artery.Under the visible guidance of fluorescence and MR dual-model imaging,the precise near-infrared(NIR)laser irradiation generated massive reactive oxygen species(ROS),which resulted in efficient plaque ablation and amplified hypoxia within VASPs.In response to the elevated hypoxia,the initially inactive TPZ was successively boosted to present potent biological suppression of foamy macrophages.After therapeutic administration of the NPs for 2 weeks,the plaque area and the degree of carotid artery stenosis were markedly reduced.Furthermore,the formulated NPs displayed excellent biocompatibility.In conclusion,the developed HSA-based NPs demonstrated appreciable specific identification ability of VASPs and realized precise synergistic regression of atherosclerosis. | Mengqi Xu Cong Mao Haoting Chen Lu Liu Yabin Wang Abid Hussain Sulei Li Xu Zhang Ruslan G.Tuguntaev Xing-Jie Liang Weisheng Guo Feng Cao | 2022 | Acta Pharmaceutica Sinica B2022，12，4： | 0 |
| 5 | 深圳,一个热爱书籍的城市显示文摘过去四天的雷阵雨并没有浇灭中国南方城市深圳的书迷的热情。深圳被联合国教科文组织评为全球推广阅读的典范。组委会宣布,7月19日至22日在深圳举行的书展平均每天接待10万名参观者。主会场深圳会展中心的图书交易总额为1076万元人民币(156万美元)。 | Tian Sulei Li Xiaoling(著) 夏天(选译) | 2019 | 中学生英语2019，0，34： | 0 |
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