| 1 | 口咽鳞状细胞癌组织中人乳头瘤病毒的检测显示文摘在世界范围内,人乳头瘤病毒(HPV)的致癌性导致口咽鳞状细胞癌(OPSCC)的发病率显著增加.随着HPV相关癌症发病率的上升,寻找可靠且准确的识别和检测HPV的工具变得非常重要.目前,虽然在OPSCC组织中检测HPV的方法已有多种,但是在灵敏度、特异性和技术难度等方面各有优缺点.本文综述了近年来应用于OPSCC组织中检测HPV的方法,包括HPV ;DNA/RNA聚合酶链反应(PCR)、环介导等温扩增(LAMP)、肿瘤蛋白16(p16)免疫组化(IHC)和DNA/RNA原位杂交分析(ISH),对选择合适的HPV检测方法具有指导意义,从而有助于HPV相关癌症的早期诊断,降低其死亡率和发病率. | Fatin Hazwani FAUZI Nurul Izzati HAMZAN Nurhayu Ab RAHMAN Siti SURAIYA Suharni MOHAMAD | 2020 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2020，21，12： | 2 |
| 3 | In-vitro antimicrobial effectiveness of herbal-based mouthrinses against oral microorganisms显示文摘Objective: To evaluate the in vitro antimicrobial effectiveness of commercial herbal-based mouthrinses against oral microorganisms. Methods: A total of three mouthrinses(OX, Pesona and Watsons) were tested for their antimicrobial activity against six oral organisms, Streptococcus mutans(S. mutans), Streptococcus sobrinus(S. sobrinus), Lactobacillus salivarius(L. salivarius), Staphylococcus aureus(S. aureus), Pseudomonas aeruginosa(P. aeruginosa) and Candida albicans(C. albicans) by standard agar-disk diffusion assay. Oradex mouthrinse containing 0.12% chlorhexidine gluconate and sterile distilled water was served as positive and negative controls, respectively. Results: All mouthrinse formulations were effective in inhibiting the growth of S. mutans, S. sobrinus, L. salivarius and C. albicans. Among the tested mouthrinses, Pesona was the only effective mouthrinse against S. aureus and P. aeruginosa, similar to Oradex mouthrinse. Pesona mouthrinse formulation appears to be as effective as Oradex mouthrinse formulation to kill S. aureus and P. aeruginosa. Statistical analysis showed no significant difference among the tested formulations regarding their antimicrobial activities(P > 0.05).Conclusions: Pesona was not the only herbal mouthrinse effective in inhibiting the growth of S. mutans, S. sobrinus, L. salivarius and C. albicans in vitro. All tested formulations were effective against those strains. Our findings may serve as a guide for selecting a kind of herbal mouthrinses as well as providing information to the dental professionals about the efficacy of these products. | Ju Ying Teh Rabiah Rawi Siti Suraiya Md Noor Haslina Taib Suharni Mohamad | 2015 | Asian Pacific Journal of Tropical Biomedicine2015，5，5： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员