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| 1 | Emergence of nanotechnology in the oil and gas industry:Emphasis on the application of silica nanoparticles显示文摘The application of nanotechnology in the oil and gas industry is on the rise as evidenced by the number of researches undertaken in the past few years.The quest to develop more game-changing technologies that can address the challenges currently facing the industry has spurred this growth.Several nanoparticles,of different sizes and at different concentrations,have been used in many investigations.In this work,the scope of the study covered the application of nanotechnology in drilling and hydraulic fracturing fluids,oilwell cementing,enhanced oil recovery(which includes transport study,and foam and emulsion stability),corrosion inhibition,logging operations,formation fines control during production,heavy oil viscosity reduction,hydrocarbon detection,methane release from gas hydrates,and drag reduction in porous media.The observed challenges associated with the use of nanoparticles are their stability in a liquid medium and transportability in reservoir rocks.The addition of viscosifier was implemented by researchers to ensure stability,and also,surface-treated nanoparticles have been used to facilitate stability and transportability.For the purpose of achieving better performance or new application,studies on synergistic effects are suggested for investigation in future nanotechnology research.The resulting technology from the synergistic studies may reinforce the current and future nanotechnology applications in the oil and gas industry,especially for high pressure and high temperature(HPHT)applications.To date,majority of the oil and gas industry nanotechnology publications are reports of laboratory experimental work;therefore,more field trials are recommended for further advancement of nanotechnology in this industry.Usually,nanoparticles are expensive;so,it will be cost beneficial to use the lowest nanoparticles concentration possible while still achieving an acceptable level of a desired performance.Hence,optimization studies are also recommended for examination in future nanotechnology research. | Muili Feyisitan Fakoya Subhash Nandlal Shah | 2017 | Petroleum2017，3，4： | 10 |
| 2 | 新型冠状病毒主要蛋白酶6YNQ黄酮类化合物抑制剂的鉴定:一项分子对接研究显示文摘目的新型冠状病毒肺炎(COVID-19)的病原体新型冠状病毒(SARS-CoV-2)是导致最近疫情全球大流行的原因,由于目前尚无针对SARS-CoV-2的有效药物或疫苗,我们研究了黄酮类化合物对抗SARS-CoV-2主要蛋白酶6YNQ的潜力。方法对SARS-CoV-2的主要蛋白酶6YNQ进行计算机模拟研究。结果所选的21种黄酮类化合物中,芦丁结合能(−8.7 kcal/mol)最高,与催化位点结合良好。结论黄酮类化合物对SARS-CoV-2主要蛋白酶6YNQ有抑制作用,这些计算模拟研究支持了黄酮类化合物可能有助于COVID-19治疗的假设。 | SUMIT Arora GOVIND Lohiya KESHAV Moharir SAPAN Shah SUBHASH Yende | 2020 | Digital Chinese Medicine2020，3，4： | 2 |
| 3 | Friction Pressure Correlations for Turbulent Fow of Drag Reducing Polymer Solutions in Straight and Coiled Tubing显示文摘 | Felipe Gallego Subhash N Shah | 2009 | Journal of Petroleum Science and Engineering2009，，65： | 1 |
| 4 | Hypoglycemic Activity of Aqueous Extract of Pleurotus pulmonarius . in Alloxan-Induced Diabetic Mice显示文摘 | Sachin L. Badole Shweta N. Shah Naimesh M. Patel Prasad A. Thakurdesai Subhash L. Bodhankar | 2006 | Pharmaceutical Biology2006，，6： | 1 |
| 5 | Analytical modeling of gas recovery from in situ hydrates dissociation显示文摘 | Naval Goel Michael Wiggins Subhash Shah | 2001 | Journal of Petroleum Science and Engineering2001，29，： | 1 |
| 6 | Analytical modeling of gas recovery from in situ hydrates dissociation显示文摘 | Naval Goel Michael Wiggins Subhash Shah | 2001 | J Petrol Sci Eng2001，29，： | 1 |
| 7 | Coiled tubing erosion during hydraulic fracturing slurry flow显示文摘 | Subhash N. Shah Samyak Jain | 2007 | Wear2007，，3： | 1 |
| 8 | 靶向TNF-α的植物抗炎先导化合物的计算机模拟筛选显示文摘目的通过计算机模拟进行分子对接,研究多种植物中的抗炎成分对肿瘤坏死因子α(TNF-α,一种参与炎症疾病的介质)的抑制作用。方法基于先前的研究,我们使用AutoDock Vina软件对不同药用植物的抗炎植物成分进行计算机模拟评估,以了解它们与TNF-α的结合模式(PDB ID:6OP0)。分子对接模拟分析中,网格箱(25×25×25)Å中心设为[-12.817×(-1.618)×19.009]Å,网格间距为0.375Å。此外,使用Discovery Studio Client 2020程序评估与靶标和配体氨基酸相关的二维和三维(2D和3D)氢键间的相互作用,并根据里宾斯基类药五规则和SwissADME数据库预测其理化性质,以支撑分子对接模拟结果。结果我们从选取的药用植物中筛选出200多种植物化合物与抗TNF-α蛋白结合,结合评分在-12.3至-2.5 kcal/mol范围内。其中,大黄素、芦荟大黄素、水黄皮籽素、紫花青素、附根含希米拉因、鞣花酸、欧前胡素、α-生育酚和八降葫芦素A表现出良好的结合亲和力,分别为-10.6、-10.0、-10.5、-10.1、-11.2、-10.3、-10.1、-10.1和-10.0 kcal/mol。此外,这些成分的吸收、分布、代谢、排泄及毒性(ADMET)特征参数均在正常范围内。结论根据初步研究结果,我们认为本研究选取的植物成分可以通过抑制TNF-α靶标成为良好的抗炎候选物。可以将这些化合物作为治疗炎症的新成分进行进一步优化和验证,以开发更加有效、安全的抗炎药物。 | Sumit Arora Pallavi Rushiya Kalpana Tirpude Nidhi Sapkal Subhash Yende Abhay Ittadwar Sapan Shah | 2022 | Digital Chinese Medicine2022，5，3： | 0 |
| 9 | Development of Composite Textile Structures for Wound Dressing Applications显示文摘The main objective of this research work was the development of novel and responsive nonwoven composite structures containing gelling materials for wound management. The development of novel all inclusive collagen booster(CB) therapeutic nonwoven wound dressings was mainly focused on. It provides essential functional properties such as high absorption,vertical and lateral wicking,and antibacterial and acidic pH properties. The developed composite wound dressing consisted of carboxymethylcellulose(CMC) fibre and also it was reinforced with polylactic acid( PLA) fibre. The produced composite wound dressings were treated with two different CBs at 4% by using the spray method. The details of the CBs have not been disclosed in this paper due to the Intellectual Property Rights( IPR) issues. The important benefit of using CB treatment is that it allows the maintenance of an acidic pH environment at the wound area. It is well known that acidic pH reduces the wound healing time and enhances the wound healing process. Furthermore,one of the CBs not only promotes the proliferation of the epithelial cells in wounds but also can provide antibacterial action. The PLA fibre reinforced CMC composite dressing has enhanced wicking properties which help to minimise the pooling of exudate on the wound bed and as a result maceration is prevented. The CBs treated dressings maintain the wound bed in an acidic pH condition which also improves the wound healing process. In addition to the above-mentioned properties,the CB treatment imparts antimicrobial activity against Gram-positive and Gram-negative bacteria,thus resulting in the reduction in the propensity for wound infection. Ultimately,the research has proved that the 4% CB treatment enhances the antimicrobial activity and the acidic pH characteristics of the developed CMC /PLA composite wound dressings. | ANAND Subhash UZUN Muhammet SHAH Tahir RAJENDRAN Subbiyan | 2013 | Journal of Donghua University(English Edition)2013，30，5： | 0 |
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