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| 1 | Decreased serum essential and aromatic amino acids in patients with chronic pancreatitis显示文摘AIM:To investigate the influence of chronic pancreatitis(CP) on serum concentrations of amino acids.METHODS:Thirty-five male patients with alcoholic CP and 21 healthy male subjects were examined.Serum concentrations of amino acids were assayed by ionpair high-performance liquid chromatography with mass detection.RESULTS:Serum glutamate concentration was increased in CP patients as compared to controls.In contrast,serum concentrations of glutamine,histidine,tyrosine,proline,tryptophan and threonine were significantly decreased in CP patients.A trend towards decreasing concentrations of serum lysine,alanine,methionine and valine as well as for total serum amino acids was observed.The sum of aromatic and the sum of essential amino acid concentrations were significantly lower in CP patients than in controls.CONCLUSION:CP leads to decreased serum concentrations of several amino acids,such as essential and aromatic serum amino acids,most likely due to decreased exocrine function. | Krystian Adrych Marian Smoczynski Magdalena Stojek Tomasz Sledzinski Ewa Slominska Elzbieta Goyke Ryszard Tomasz Smolenski Julian Swierczynski | 2010 | World Journal of Gastroenterology2010,16,35: | 3 |
| 2 | Decreased serum platelet derived growth factor BB levels in acute and increased in chronic pancreatitis显示文摘AIM: To examine circulating growth factor concentrations in patients with acute pancreatitis(AP) and chronic pancreatitis(CP), and walled-off pancreatic necrosis(WOPN). METHODS: Forty patients with mild AP, 40 patients with alcoholic CP, 33 patients with WOPN and 40 healthy subjects were examined. Serum concentrations of platelet derived growth factor BB(PDGF-BB), transforming growth factor β-1(TGFβ-1), chemerin and high-mobility group box chromosomal protein 1(HMBG1) were assayed by enzyme linked immunosorbent assay.RESULTS: Patients with mild AP and those with WOPN had significantly lower serum levels of PDGF-BB compared to healthy subjects(4.0 ± 0.61 ng/mL vs 6.2 ± 0.76 ng/mL, P = 0.027, and 1.60 ± 0.31 ng/mL vs 6.2 ± 0.76 ng/mL, P < 0.001, respectively), while CP was associated with higher serum levels of PDGF-BB(12 ± 1.3 ng/mL vs 6.2 ± 0.76 ng/mL, P < 0.001). Circulating TGFβ-1 and chemerin levels were elevated in CP patients(57 ± 3.6 ng/mL vs 39 ± 3.6 ng/mL, P < 0.001 and 73 ± 7.2 ng/mL vs 48 ± 2.3 ng/mL, P < 0.001, respectively), but not in patients with AP and WOPN. No significant changes in serum HMBG1 levels were found either in patients with AP, WOPN or CP. CONCLUSION: The serum levels of some growth factors and cytokines differ significantly in AP, WOPN and CP. These data suggest that selected growth factors and cytokines may be considered as potential diagnostic biomarkers in patients with pancreatic diseases. | Magdalena Stojek Krystian Adrych Lukasz Rojek Marian Smoczynski Tomasz Sledzinski Sylwia Szrok Julian Swierczynski | 2014 | World Journal of Gastroenterology2014,20,36: | 2 |
| 3 | Dynamic model of axial piston swash-plate pump for diagnostics of wear in elements显示文摘 | Waldemar latas Jerzy Stojek | 2011 | Archive of Mechanical Engineering2011,58,2: | 1 |
| 4 | Thinness and restricting expectancies mediate the influence of ethnic identity on bulimic symptoms显示文摘 | Stojek M Fischer S Collins B | 2010 | Pers lndiv Differ2010,49,2: | 1 |
| 5 | Legionella in sprinkling water as a potential occupational risk factor for gardeners 显示文摘 | Stojek NM Dutkiewicz J | 2002 | Ann Agric Environ Med2002,9,: | 1 |
| 6 | Micromolar concentrations of 2-methoxyestradiol kill glioma cells by an apoptotic mechanism without destroying their microtubule cytoskeleton显示文摘 | Chamaon K Stojek J Kanakis D | | 0,,01: | 1 |
| 7 | Electrodeposition and prop- erties of Fe-W and Fe-Ni-W amorphous alloys显示文摘 | Donten M Cesiulis H Stojek Z | 2000 | Electro- chimica Acta2000,45,20: | 1 |
| 8 | Role of adipokines in complications related to obesity:a review显示文摘 | Gnacińska M Malgorzewicz S Stojek M | 2009 | Adv Med Sci2009,54,2: | 1 |
| 9 | Thermoresponsive Poly (N-Isopropylacry-lamide) Gel for Immobilization of Laccase on Indium Tin Oxide Electrodes 显示文摘 | Klis M Karbarz M Stojek Z | 2009 | J Phys Chem B2009,113,: | 1 |
| 10 | Craving as an alcohol use disorder symptom in DSM - 5 : an empirical examination in a treatment -seeking sample显示文摘 | Murphy CM Stojek MK Few LR | 2014 | Exp Clin Psychopharm2014,22,: | 1 |
| 11 | Micromolar concentrations of 2-methoxyestradiol kill glioma cells by an apoptotic mechanism,without destroying their microtubule cytoskeleton显示文摘 | Chamaon K Stojek J Kanakis D | 2005 | J Neurooncol2005,72,1: | 1 |
| 12 | Least-Squares Trefftz-Type Elements for the Helmholtz Eqaution 显示文摘 | Stojek M | 1998 | Int J Numer Meth Eng1998,41,83: | 1 |
| 13 | Thermoresponsive Poly (N-Isopropylacrylamide) Gel for Immobilization of Laccase on Indium Tin Oxide Electrodes 显示文摘 | Klis M Karbarz M Stojek Z | 2009 | J Phys Chem B2009,113,17: | 1 |
| 14 | Thermoresponsive Poly(N-Isopropylacry-lamide) Gel for Immobilization of Laccase on Indium Tin Oxide Electrod显示文摘 | Klis M Karbarz M Stojek Z | 2009 | J Phys Chem B2009,113,: | 1 |
| 15 | Electrodeposition and properties of Ni-W, Fe-W and Fe-Ni-W amorphous alloys: A comparative study 显示文摘 | Donten M Cesiulis H Stojek Z | 2000 | Electrochimica Acta2000,45,20: | 1 |
| 16 | Thermoresponsive poly(N-isopropylacrylamide)gel for immobilization of laccase on indium tin oxide electrodes显示文摘 | KLIS M KARBARZ M STOJEK Z ROGALSKI J BILEWICZ R | 2009 | J Phys Chem B2009,113,17: | 1 |
| 17 | Interrelationships among impulsive personality traits, food addiction, and body mass index显示文摘 | Murphy CM Stojek MK MacKillop J | 2014 | Appetite2014,73,: | 1 |
| 18 | Micromolar concentrations of 2-methoxyestradiol kill glioma cells by an apoptotic mechanism,without destroying their microtubule cytoskeleton显示文摘 | CHAMAON K STOJEK J KANAKIS D | 2005 | J Neurooncol2005,72,1: | 1 |
| 19 | The interface between metallic substrates and layers of electrodeposited Co-W amorphous alloys显示文摘 | Gromulski T Stojek Z | 1998 | Journal of Alloys and Compounds1998,279,2: | 1 |
| 20 | Research on the Properties of Hydrostatic Transmission for Different Effi- ciency Models of Its Elements 显示文摘 | JEDRKIEWICZ Z PLUTA J STOJEK J | 1997 | Acta Montanistica Slo- vaca1997,2,4: | 1 |