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| 1 | High-resolution flood modeling of urban areas using MSN_Flood显示文摘Although existing hydraulic models have been used to simulate and predict urban flooding, most of these models are inadequate due to the high spatial resolution required to simulate flows in urban floodplains. Nesting high-resolution subdomains within coarser-resolution models is an efficient solution for enabling simultaneous calculation of flooding due to tides, surges, and high river flows. MSN_Flood has been developed to incorporate moving boundaries around nested domains, permitting alternate flooding and drying along the boundary and in the interior of the domain. Ghost cells adjacent to open boundary cells convert open boundaries, in effect, into internal boundaries. The moving boundary may be multi-segmented and non-continuous, with recirculating flow across the boundary. When combined with a bespoke adaptive interpolation scheme, this approach facilitates a dynamic internal boundary. Based on an alternating-direction semi-implicit finite difference scheme,MSN_Flood was used to hindcast a major flood event in Cork City resulting from the combined pressures of fluvial, tidal, and storm surge processes. The results show that the model is computationally efficient, as the 2-m high-resolution nest is used only in the urban flooded region.Elsewhere, lower-resolution nests are used. The results also show that the model is highly accurate when compared with measured data. The model is capable of incorporating nested sub-domains when the nested boundary is multi-segmented and highly complex with lateral gradients of elevation and velocities. This is a major benefit when modelling urban floodplains at very high resolution. | Michael Hartnett Stephen Nash | 2017 | Water Science and Engineering2017，10，3： | 3 |
| 2 | Observation and modeling of tide- and wind-induced surface currents in Galway Bay显示文摘A high-frequency radar system has been deployed in Galway Bay, a semi-enclosed bay on the west coast of Ireland. The system provides surface currents with fine spatial resolution every hour. Prior to its use for model validation, the accuracy of the radar data was verified through comparison with measurements from acoustic Doppler current profilers(ADCPs) and a good correlation between time series of surface current speeds and directions obtained from radar data and ADCP data. Since Galway Bay is located on the coast of the Atlantic Ocean, it is subject to relatively windy conditions, and surface currents are therefore strongly wind-driven. With a view to assimilating the radar data for forecasting purposes, a three-dimensional numerical model of Galway Bay, the Environmental Fluid Dynamics Code(EFDC), was developed based on a terrain-following vertical(sigma) coordinate system. This study shows that the performance and accuracy of the numerical model, particularly with regard to tide- and wind-induced surface currents, are sensitive to the vertical layer structure. Results of five models with different layer structures are presented and compared with radar measurements. A variable vertical structure with thin layers at the bottom and the surface and thicker layers in the middle of the water column was found to be the optimal layer structure for reproduction of tide- and wind-induced surface currents. This structure ensures that wind shear can properly propagate from the surface layer to the sub-surface layers, thereby ensuring that wind forcing is not overdamped by tidal forcing. The vertical layer structure affects not only the velocities at the surface layer but also the velocities further down in the water column. | Lei Ren Stephen Nash Michael Hartnett | 2015 | Water Science and Engineering2015，8，4： | 1 |
| 3 | Can the agency costs of debt and equity explain the changes in executive compensation during the 1990s?显示文摘 | Bryan Stephen Robert Nash and Ajay Patel | 2006 | Journal of Co rporate Finance2006，12，3： | 1 |
| 4 | Is scleroderma a vasculopathy?显示文摘 | Jo Nadine Fleming Richard A. Nash William M. Mahoney Stephen Mark Schwartz | 2009 | Current Rheumatology Reports2009，，2： | 1 |
| 5 | Regional modelling of the 21st century climate chang- es in the Irish Sea显示文摘 | AGNIESZKA I OLBERT TOMASZ DABROWSKI STEPHEN NASH | 2012 | Continental Shelf Research2012，41，： | 1 |
| 6 | An integrated measurement and modeling methodology for estuarine water quality management显示文摘This paper describes research undertaken by the authors to develop an integrated measurement and modeling methodology for water quality management of estuaries. The approach developed utilizes modeling and measurement results in a synergistic manner. Modeling results were initially used to inform the field campaign of appropriate sampling locations and times, and field data were used to develop accurate models.Remote sensing techniques were used to capture data for both model development and model validation. Field surveys were undertaken to provide model initial conditions through data assimilation and determine nutrient fluxes into the model domain. From field data, salinity relationships were developed with various water quality parameters, and relationships between chlorophyll a concentrations, transparency, and light attenuation were also developed. These relationships proved to be invaluable in model development, particularly in modeling the growth and decay of chlorophyll a. Cork Harbour, an estuary that regularly experiences summer algal blooms due to anthropogenic sources of nutrients,was used as a case study to develop the methodology. The integration of remote sensing, conventional fieldwork, and modeling is one of the novel aspects of this research and the approach developed has widespread applicability. | Michael Hartnett Stephen Nash | 2015 | Water Science and Engineering2015，8，1： | 1 |
| 7 | Truncated Newton-Based Multigrid Algorithm for Centroidal Voronoi Diagram Calculation显示文摘In a variety of modern applications there arises a need to tessellate the domain into representative regions,called Voronoi cells.A particular type of such tessellations,called centroidal Voronoi tessellations or CVTs,are in big demand due to their optimality properties important for many applications.The availability of fast and reliable algorithms for their construction is crucial for their successful use in practical settings.This paper introduces a new multigrid algorithm for constructing CVTs that is based on the MG/Opt algorithm that was originally designed to solve large nonlinear optimization problems.Uniform convergence of the new method and its speedup comparing to existing techniques are demonstrated for linear and nonlinear densities for several 1d and 2d problems,and O(k)complexity estimation is provided for a problem with k generators. | Zichao Di Maria Emelianenko Stephen Nash | 2012 | Numerical Mathematics(Theory,Methods and Applications)2012，5，2： | 1 |
| 8 | Ancient DNA of the pygmy marmoset type specimen Cebuella pygmaea(Spix,1823)resolves a taxonomic conundrum显示文摘The pygmy marmoset,the smallest of the anthropoid primates,has a broad distribution in Western Amazonia.Recent studies using molecular and morphological data have identified two distinct species separated by the Napo and Solimoes-Amazonas rivers.However,reconciling this new biological evidence with current taxonomy,i.e.,two subspecies,Cebuella pygmaea pygmaea(Spix,1823)and Cebuella pygmaea niveiventris(Lönnberg,1940),was problematic given the uncertainty as to whether Spix’s pygmy marmoset(Cebuella pygmaea pygmaea)was collected north or south of the Napo and Solimoes-Amazonas rivers,making it unclear to which of the two newly revealed species the name pygmaea would apply.Here,we present the first molecular data from Spix’s type specimen of Cebuella pygmaea,as well as novel mitochondrial genomes from modern pygmy marmosets sampled near the type locality(Tabatinga)on both sides of the river.With these data,we can confirm the correct names of the two species identified,i.e.,C.pygmaea for animals north of the Napo and Solimoes-Amazonas rivers and C.niveiventris for animals south of these two rivers.Phylogenetic analyses of the novel genetic data placed into the context of cytochrome b gene sequences from across the range of pygmy marmosets further led us to reevaluate the geographical distribution for the two Cebuella species.We dated the split of these two species to 2.54 million years ago.We discuss additional,more recent,subdivisions within each lineage,as well as potential contact zones between the two species in the headwaters of these rivers. | Jean P.Boubli Mareike C.Janiak Leila M.Porter Stella de la Torre Liliana Cortes-Ortiz Maria N.Fda Silva Anthony B.Rylands Stephen Nash Fabricio Bertuol Hazel Byrne Felipe E.Silva Fabio Rohe Dorien de Vries Robin M.D.Beck Irune Ruiz-Gartzia Lukas F.K.Kuderna Tomas Marques-Bonet Tomas Hrbek Izeni P.Farias Anneke Hvan Heteren Christian Roos | 2021 | Zoological Research2021，42，6： | 1 |
| 9 | Intrinsic Photoconductivity of Few-layered ZrS2 Phototransistors via Multiterminal Measurements显示文摘We report intrinsic photoconductivity studies on one of the least examined layered compounds,ZrS2.Few-atomic layer ZrS2 field-effect transistors were fabricated on the Si/SiO2 substrate and photoconductivity measurements were performed using both two-and four-terminal configurations under the illumination of 532 nm laser source.We measured photocurrent as a function of the incident optical power at several source-drain(bias)voltages.We observe a significantly large photoconductivity when measured in the multiterminal(four-terminal)configuration compared to that in the two-terminal configuration.For an incident optical power of 90 nW,the estimated photosensitivity and the external quantum efficiency(EQE)measured in two-terminal configuration are 0.5 A/W and 120%,respectively,under a bias voltage of 650 mV.Under the same conditions,the four-terminal measurements result in much higher values for both the photoresponsivity(R)and EQE to 6 A/W and 1400%,respectively.This significant improvement in photoresponsivity and EQE in the four-terminal configuration may have been influenced by the reduction of contact resistance at the metal-semiconductor interface,which greatly impacts the carrier mobility of low conducting materials.This suggests that photoconductivity measurements performed through the two-terminal configuration in previous studies on ZrS2 and other 2D materials have severely underestimated the true intrinsic properties of transition metal dichalcogenides and their remarkable potential for optoelectronic applications. | Rukshan M.Tanthirige Carlos Garcia Saikat Ghosh Frederick Jackson II Jawnaye Nash Daniel Rosenmann Ralu Divan Liliana Stan Anirudha V.Sumant Stephen A.McGill Paresh C.ay Nihar R.Pradhan | 2019 | Semiconductor Science and Information Devices2019，1，2： | 0 |
| 10 | 雷诺嗪治疗稳定型心绞痛显示文摘雷诺嗪是唯一一种被批准用于治疗慢性稳定型心绞痛的新药。该药已被制成缓释剂型应用于临床。尽管雷诺嗪的作用机制尚未完全阐明,但目前的观点认为,雷诺嗪是一种选择性晚期钠内流抑制剂,可减弱与缺血相关的心室复极和收缩的异常。3项随机试验证实了雷诺嗪在改善运动试验、减少心绞痛发作和减少硝酸甘油使用的效应。其不良反应包括眩晕、便秘、恶心和潜在的QTC间期延长作用。在现有的传统药物(尤其是积极的多药联合方案)基础上加用雷诺嗪治疗慢性稳定型心绞痛是安全的。 | David T Nash Stephen D Nash | 2009 | 世界临床医学2009，，7： | 0 |
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