|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Homeodomain leucine-zipper proteins and their role in synchronizing growth and development with the environment显示文摘The Arabidopsis(Arabidopsis thaliana L.) genome Minireviewencodes for four distinct classes of homeodomain leucine-zipper(HD-ZIP) transcription factors(HD-ZIPI to HD-ZIPIV),which are all organized in multi-gene families. HD-ZIP transcription factors act as sequence-specific DNA-binding proteins that are able to control the expression level of target genes. While HD-ZIPI and HD-ZIPII proteins are mainly associated with environmental responses, HD-ZIPIII and HD-ZIPIV are primarily known to act as patterning factors.Recent studies have challenged this view. It appears that several of the different HD-ZIP families interact genetically to align both morphogenesis and environmental responses, most likely by modulating phytohormone-signaling networks. | Ronny Brt Marc Cabedo Yakun Xie Stephan Wenkel | 2014 | Journal of Integrative Plant Biology2014，56，6： | 9 |
| 2 | Detection of Coronary Artery Stenoses by Contrast-Enhanced, Retrospectively Electrocardiographically-Gated, Multislice Spiral Computed Tomography显示文摘 | Stephan Achenbach Tom Giesler Dieter Ropers Stefan Ulzheimer Hans Derlien Christoph Schulte Evelyn Wenkel Werner Moshage Werner Bautz Werner G. Daniel Willi A. Kalender Ulrich Baum | 2001 | Circulation: Journal of the American Heart Association2001，，21： | 1 |
| 3 | 2006, CONSTANS and the CCAAT box binding complex share a function- ally important domain and interact to regulate flowering of Arabidopsis显示文摘 | Stephan Wenkel Turck F Singer K | 2006 | Plant Cell2006，18，11： | 1 |
| 4 | Detection of Coronary Artery Stenoses by Contrast-Enhanced, Retrospectively Electrocardiographically-Gated, Multislice Spiral Computed Tomography显示文摘 | Stephan Achenbach Tom Giesler Dieter Ropers Stefan Ulzheimer Hans Derlien Christoph Schulte Evelyn Wenkel Werner Moshage Werner Bautz Werner G. Daniel Willi A. Kalender Ulrich Baum | 2001 | Circulation: Journal of the American Heart Association2001，，21： | 1 |
| 5 | Controlling flowering of Medicago sativa(alfalfa)by inducing dominant mutations显示文摘Breeding plants with polyploid genomes is challenging because functional redundancy hampers the identification of loss-of-function mutants.Medicago sativa is tetraploid and obligate outcrossing,which together with inbreeding depression complicates traditional breeding approaches in obtaining plants with a stable growth habit.Inducing dominant mutations would provide an alternative strategy to introduce domestication traits in plants with high gene redundancy.Here we describe two complementary strategies to induce dominant mutations in the M.sativa genome and how they can be relevant in the control of flowering time.First,we outline a genome-engineering strategy that harnesses the use of microProteins as developmental regulators.MicroProteins are small proteins that appeared during genome evolution from genes encoding larger proteins.Genomeengineering allows us to retrace evolution and create microProtein-coding genes de novo.Second,we provide an inventory of genes regulated by microRNAs that control plant development.Making respective gene transcripts microRNA-resistant by inducing point mutations can uncouple microRNA regulation.Finally,we investigated the recently published genomes of M.sativa and provide an inventory of breeding targets,some of which,when mutated,are likely to result in dominant traits. | Maurizio Junior Chiurazzi Anton Frisgaard Nørrevang Pedro García Pablo D.Cerdán Michael Palmgren Stephan Wenkel | 2022 | Journal of Integrative Plant Biology2022，64，2： | 1 |
| 6 | Control of flowering in rice through synthetic microProteins显示文摘Photoperiod-dependent flowering in rice is regulated by HEADING DATE 1(Hd1),which acts as both an activator and repressor of flowering in a daylengthdependent manner.To investigate the use of microProteins as a tool to modify rice sensitivity to the photoperiod,we designed a synthetic Hd1 micro Protein(Hd1miP)capable of interacting with Hd1 protein,and overexpressed it in rice.Transgenic OX-Hd1 miP plants flowered significantly earlier than wild type plants when Breakt grown in non-inductive long day conditions.Our results show the potential of microProteins to serve as powerful tools for modulating crop traits and unraveling protein function. | Tenai Eguen Jorge Gomez Ariza Vittoria Brambilla Bin Sun Kaushal Kumar Bhati Fabio Fornara Stephan Wenkel | 2020 | Journal of Integrative Plant Biology2020，62，6： | 0 |
| 7 | MicroProteins:Expanding functions and novel modes of regulation显示文摘MicroProteins are small,5-15-kDa single-domain proteins that are evolutionarily related to multi-domain proteins with sequence homology(Eguen et al.,2015).The single domain of microProteins is often a protein-protein interaction(PPI)-domain,through which they can interact with their multi-domain protein targets(Figure 1).The first experimental insight that microProteins exist and how they act came from the identification of the regulatory feedback mechanism of class III homeodomain-leucine zipper(HD-ZIPIII)transcription factors by LITTLE ZIPPER(ZPR)microProteins(Wenkel et al.,2007;Kim et al.,2008).In Arabidopsis,the LITTLE ZIPPER microProtein family consists of four members(ZPR1-4)containing only a leucine zipper domain.The HD-ZIPIII transcription factor REVOLUTA directly transcriptionally upregu-lates multiple ZPR genes.ZPR proteins physically interact with their HD-ZIPIII targets and suppress their DNA binding ability. | Kaushal Kumar Bhati Ulla Dolde Stephan Wenkel | 2021 | Molecular Plant2021，14，5： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员