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| 1 | A randomized controlled study of low-dose UVA1,medium-dose UVA1,and narrowband UVB phototherapy in the treatment of localized scleroderma显示文摘 | Kreuter A Hyun J Stücker M | | 0，，03： | 1 |
| 2 | Review of published information on foam sclerotherapy显示文摘 | Stücker M Kobus S Altmeyer P | 2010 | Dermatol Surg2010，362，： | 1 |
| 3 | Semen-derivedamyloid fibrils drastically enhance HIV infection显示文摘 | Münch J Rücker E Stndker L | 2007 | Cell2007，131，6： | 1 |
| 4 | A randomized controlled study of low-dose UVA1,medium-dose UVA1,and narrow-band UVB phototherapy in the treatment of localized scleroderma显示文摘 | Kreuter A Hyun J Stücker M | 2006 | J Am Acad Der-matol2006，54，3： | 1 |
| 5 | 小剂量UVA1、中剂量UVA1和窄波UVB光疗法治疗局限性硬皮病的随机对照研究显示文摘Background: In previous trials, UV therapy has been demon- strated to be effective in the treatment of localized scleroderma (LS). To date, a randomized comparison study to evaluate the efficacy and safety of different, commonly used phototherapeutic modalities in LS is still outstanding. Objective: The aim of this study was to compare the safety and efficacy of lowdose (LD) UVA1, medium- dose (MD) UVA1, and narrowband (NB)UVB phototherapy in the treatment of LS.Methods: Sixty four patients with LS were consecutively included in a prospective, open, randomized controlled 3- arm study. Severity of LS was determined by means of a clinical score, and clinical improvement was also monitored by histopathologic analysis and 20- MHz ultrasound. Results: Atotal of 27 patients were treated with LD UVA1 (20 Jcm2), 18 patients receivedMD UVA1 (50 Jcm2), and 19 patients were treated with NB UVB dependent on their skin type. Phototherapy was performed 5 times weekly for 8 weeks. Two of the 64 patients included in this trial discontinued therapy. Skin status significantly improved in all patients who finished the treatment protocol, resulting in a reduction of the clinical score in all groups (LD UVA1, 7.6- 5.0 [P < .001,95% confidence interval 1.6- 3.4]; MD UVA1, 11.1- 6.6 [P < .001, 95% confidence interval 2.5- 6.2]; NB UVB, 7.3- 4.9 [P< .001, 95% confidence interval 1.6- 3.2]). The reduction of the score was accompanied by an improvement of the visual analog scale for itching and tightness, histologic score, and 20- MHz ultrasound. MD UVA1 was significantly more effective than NB UVB (P < .05). There were no significant differences between LDUVA1 and NBUVB and the former and MDUVA1 (P > .05). Limitations: We had a relatively small study sample and nonblinded assessment of primary outcome. Conclusion: Phototherapy, as previously reported in several noncontrolled trials, is an effective therapeutic option in LS, with a favorable riskbenefit ratio. UVA1 phototherapy should be considered among the first approaches in the management of LS. | Kreuter A. Hyun J. Stü cker M. 李政霄 | 2006 | 世界核心医学期刊文摘(皮肤病学分册)2006，0，4： | 1 |
| 6 | 延胡索酸酯类治疗类脂质渐进性坏死的前瞻性非对照研究显示文摘Background: Necrobiosis lipoidica (NL) is an uncommongranulomatous skin diseas ewith association to diabetesmellitus. To date, no proven effective therapy for NL has been implemented. The standard treatment is topical application of cortic osteroids, but numerous agents have been reported for NL, with varying varying d egrees of success. In recent case reports, fumaric acid esters (FAE) have been r eported to be effective in granulomatous skin diseases such as granuloma annular e, cutaneous sarcoidosis and NL. Objectives We sought to investigate the efficac y of FAE in a larger number of patients with NL. Methods Eighteen patients with histopathologically proven NL were consecutively recruited into a prospective no ncontrolled study. Dosage of FAE was given according to the standard therapy reg imen for psoriasis. FAE were administered for at least 6 months. The treatment o utcome was evaluated by means of clinical and histological scoring and 20-MHz u ltrasound assessments. Results Three patients discontinued therapy with FAE, whi le the remaining 15 patients finished the study. After amean ±SD treatment peri od of 7.7 ±2.9months, a significant (P < 0.001) decrease in the mean ±SD clini cal score, from 7.4 ±1.8 at the beginning to 2.5 ±1.3 at the end of therapy, w as observed. Significant clinical improvement of NL was accompanied by significa nt (P=0.019) increase of dermal density as assessed by means of 20-MHz ultrasou nd, and significant (P =0.011) reduction of the histological score. Adverse effe cts were moderate and consisted mainly of gastrointestinal complaints and flushi ng. During follow-up of at least 6 months, clinical outcome remained stable in all patients. Conclusions The results of this study demonstrate that FAE are ben eficial and safe in the treatment of patients with NL. | Kreuter A Knierim C Stücker M 罗素菊 | 2006 | 世界核心医学期刊文摘(皮肤病学分册)2006，0，1： | 0 |
| 7 | Expression of a stilbene synthase gene in Nicotiana tabacum results in synthesis of the phytoalexin resveratrol显示文摘 | Rüdiger Hain Barbara Bieseler Helmut Kindl Gudrun Schr?der Ronald St?cker | 1990 | Plant Molecular Biology1990，，2： | 1 |
| 8 | 多系统萎缩中部分排汗功能紊乱(德国) | Saft C. Andrich J. Mü ller T. M. Stü cker 刘安 | 2005 | 世界核心医学期刊文摘(皮肤病学分册)2005，0，12： | 0 |
| 9 | Rapid detection of loss of heterozygosity of chromosome 17p by polymerase chain reaction-based variable number of tandem repeat analysis and detection of single-strand conformation polymorphism of intragenic p53 polymorphisms显示文摘 | B. Dockhorn-Dworniczak C. Poremba R. Dantcheva A. Stücker E. Br?mmelkamp S. Blasius W. B?cker W. Mellin A. Roessner D. Yandell | 1994 | Virchows Archiv1994，，4： | 1 |
| 10 | Residual Stumps Associated with Inguinal Varicose Vein Recurrences: A Multicenter Study显示文摘 | B. Geier M. Stücker T. Hummel P. Burger N. Frings M. Hartmann D. Stenger C. Schwahn-Schreiber M. Schonath A. Mumme | 2008 | European Journal of Vascular & Endovascular Surgery2008，，2： | 1 |
| 11 | Acute skin alterations following ultraviolet radiation investigated by optical coherence tomography and histology显示文摘 | Thilo Gambichler Stefanie Boms Markus Stücker Georg Moussa Alexander Kreuter Michael Sand Daniel Sand Peter Altmeyer Klaus Hoffmann | 2005 | Archives of Dermatological Research2005，，5： | 1 |
| 12 | The IAPWS industrial formulation 1997 for the thermodynamic properties of water and steam显示文摘 | Wagner W Cooper J.R Dittmann A Kijima J Kretzschmar H.J Kruse A Mare(s) R Oguchi K Sato H St(o)cker I (S)ifner O Takaishi Y Tanishita I Trübenbach J Willkommen Th | | 0，，01： | 1 |
| 13 | Pooled analysis of the CYP1A1 exon 7 polymorphism and lung cancer (United States)显示文摘 | Lo?c Le Marchand Chuanfa Guo Simone Benhamou Christine Bouchardy Ingolf Cascorbi Margie L. Clapper Seymour Garte Aage Haugen Magnus Ingelman-Sundberg Masahiro Kihara Agneta Rannug David Ryberg Isabelle Stücker Haruhiko Sugimura Emanuela Taioli | 2003 | Cancer Causes and Control2003，，4： | 1 |
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