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| 1 | Operative vs non-operative management of displaced proximal humeral fractures in the elderly: A systematic review and meta-analysis of randomized controlled trials显示文摘AIM: To perform a systematic review and meta-analysis comparing operative vs non-operative treatment of displaced proximal humerus fractures in elderly patients.METHODS: A systematic literature search was performed using EMBASE and MEDLINE through the OVID interface,CINAHL,the Cochrane Central Register of Controlled Trials(CENTRAL),Proquest,Web of Science,SAE digital library,and Transportation Research Board's TRID database.Searches of conference proceedings were also conducted.All available randomized controlled trials comparing operative vs non-operative management of displaced three- and four-part proximal humerus fractures in elderly patients were included.The primary outcomes measures included physical function,pain,health related quality of life,mortality,and the re-operation rate.RESULTS: Six randomized controlled trials(n = 287) were included.There was no statistically significant difference in function(MD = 1.72,95%CI:-2.90-6.34,P = 0.47),as measured by the Constant score,between the operative and the non-operative treatment groups.There was no statistically significance difference insecondary outcomes of health related quality of life(standardized MD = 0.27,95%CI:-0.05-0.59,P = 0.09),and mortality(relative risk 1.29,95%CI: 0.50-3.35,P = 0.60).Operative treatment had a statistically significant higher re-operation rate(relative risk 4.09,95%CI: 1.50-11.15,P = 0.006),and statistically significant decreased pain(MD = 1.26,95%CI: 0.02-2.49,P = 0.05).CONCLUSION: There is moderate quality evidence to suggest that there is no difference in functional outcomes between the two treatments.Further high quality randomized controlled trials are required to determine if certain subgroup populations benefit from surgical management. | Santa Rabi Nathan Evaniew Sheila A Sprague Mohit Bhandari Gerard P Slobogean | 2015 | World Journal of Orthopedics2015，6，10： | 5 |
| 2 | Depositional architec- ture and sequence stratigraphy of the Karoo basin floor to shelf edge succession, Laingsburg depocentre, South Africa显示文摘 | Flint S S Hodgson D M Sprague A R | 2010 | Marine and Pe- troleum Geology2010，27，1： | 1 |
| 3 | Effect of epistasis on grain yield in maize显示文摘 | Sprague G E Russel W A Penny L H | 1962 | Crop Sci1962，2，： | 1 |
| 4 | Tech- nique for Monolithic Fabrication of Microlens Arrays 显示文摘 | POPVIC Z D SPRAGUE R A CONNEL G A N | 1988 | Applied Optics1988，27，7： | 1 |
| 5 | General versus specific combining ability in single crosses of corn 显示文摘 | Sprague G F Tatum L A | 1942 | Jour Amer Soc Agron1942，，34： | 1 |
| 6 | Inflammatory cytokines in vascular dys- function and vascular disease 显示文摘 | Sprague A H Khalil R A | 2009 | Biochem Pharmacol2009，78，6： | 1 |
| 7 | A spectral-element method for modeling cavitation in transient fluid-structure in- teraction 显示文摘 | Sprague M A Geers T L | 2004 | International Journal for Numerical Methods in Engineering2004，60，15： | 1 |
| 8 | General vs specific combining ability in single crosses of corn显示文摘 | Sprague G F Tatum L A | 1942 | J Am Soc Agron1942，34，： | 1 |
| 9 | General and specific combining ability in single crosses of corn显示文摘 | Sprague G F Tatum L A | 1942 | Journal of the American Society of Agronomy1942，34，4： | 1 |
| 10 | Use of vitamin D in chronic kidney disease patients显示文摘 | GaI-Moscovici A Sprague S M | 2010 | Kidney Int2010，78，2： | 1 |
| 11 | Interpretive tools for 3D structural geological modeling part I: Bezier-based curves, rib- bons and grip frames显示文摘 | DE KEMP E A SPRAGUE K B | 2003 | Geoinformatica2003，7，1： | 1 |
| 12 | Interpretive tools for 3D structural geological modelling Part Ⅱ: Surface design from sparse spatial data显示文摘 | SPRAGUE K B DE KEMP E A | 2005 | Geoinformatica2005，9，1： | 1 |
| 13 | A modern view of atherogen- esis显示文摘 | Schwartz CJ Valente A J Sprague EA | 1993 | Am J Cardiol1993，71，： | 1 |
| 14 | Response of empty and fluid- filled submerged spherical shells to plane and spherical, step-exponential acoustic waves 显示文摘 | SPRAGUE M A GEERS T L | 1999 | Shock and Vibration1999，，6： | 1 |
| 15 | Lethal levels of mixed copperzinc solutions for Juvenile Salmon显示文摘 | Sprague J B Ramsay B A | 1965 | J Fish Res Bd Can1965，22，： | 1 |
| 16 | Examining caesarean section rates in Canada using the Robson classification system显示文摘 | Kelly S Sprague A Fell DB et a1 | 2013 | J Obstet Gynaecol Can2013，35，3： | 1 |
| 17 | Use of vitamin D in chronic kid- ney disease patients 显示文摘 | Gal-Moscovici A Sprague SM | 2010 | Kidney Int2010，78，2： | 1 |
| 18 | General vs specific combining ability in single crosses of corn显示文摘 | Sprague G F Tatum L A | 1942 | J Am Soc Agrom1942，34，4： | 1 |
| 19 | Lethal levels of mixed copper-zinc solutions for juvenile salmon显示文摘 | Sprague J B Ramsay B A | 1965 | Journal of the Fisheries Research Board of Canada1965，22，2： | 1 |
| 20 | Role of vitamin D deficiency in chronic kidney disease 显示文摘 | Gal-Moscovici A Sprague SM | 2007 | J Bone Miner Res2007，22，2： | 1 |
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