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| 1 | A randomized open-label trial of on-demand rabeprazole vs ranitidine for patients with non-erosive reflux disease显示文摘AIM:To compare the efficacy of the proton-pump inhibitor,rabeprazole,with that of the H 2-receptor antagonist,ranitidine,as on-demand therapy for relieving symptoms associated with non-erosive reflux disease(NERD).METHODS:This is a single center,prospective,randomized,open-label trial of on-demand therapy with rabeprazole(group A) vs ranitidine(group B) for 4 wk.Eighty-three patients who presented to the American University of Beirut Medical Center with persistent gastroesophageal reflux disease(GERD) symptoms and a normal upper gastrointestinal endoscopy were eligible for the study.Patients in group A(n = 44) were allowed a maximum rabeprazole dose of 20 mg twice daily,while those in group B(n = 39) were allowed a maximum ranitidine dose of 300 mg twice daily.Efficacy was assessed by patient evaluation of global symptom relief,scores of the SF-36 quality of life(QoL) questionnaires,total number of pills used,and number of medication-free days.RESULTS:Among the 83 patients who were enrolled in the study,76 patients(40 in the rabeprazole group and 36 in the ranitidine group) completed the 4-wk trial.Baseline characteristics were comparable between both groups.After 4 wk,there was no significant difference in the subjective global symptom relief between the rabeprazole and the ranitidine groups(71.4% vs 65.4%,respectively;P = 0.9).There were no statistically significant differences between mean cumulative scores of the SF-36 QoL questionnaire for the two study groups(rabeprazole 22.40 ± 27.53 vs ranitidine 17.28 ± 37.06;P = 0.582).There was no significant difference in the mean number of pills used(rabeprazole 35.70 ± 29.75 vs ranitidine 32.86 ± 26.98;P = 0.66).There was also no statistically significant difference in the mean number of medication-free days between both groups.CONCLUSION:Rabeprazole has a comparable efficacy compared to ranitidine when given on-demand for the treatment of NERD.Both medications were associated with improved quality of life. | Abdallah A Kobeissy Jana G Hashash Faek R Jamali Assaad M Skoury Reham Haddad Sarah El-Samad Rami Ladki Rola Aswad Assaad M Soweid | 2012 | World Journal of Gastroenterology2012，18，19： | 4 |
| 2 | Endoscopic ultrasound-guided celiac plexus neurolysis显示文摘Endoscopic celiac plexus neurolysis(CPN)has become the procedure of choice for the management of patients with pancreatic cancer and abdominal pain unresponsive to medical treatment.It is necessary to differentiate between CPN and endoscopic celiac plexus block performed in patients with benign disease.In this review we describe the technique of this procedure with special emphasis on technical details. | Assaad M Soweid Cecilio Azar | 2010 | World Journal of Gastrointestinal Endoscopy2010，2，6： | 3 |
| 3 | Posterior lingual lidocaine: A novel method to improve tolerance in upper gastrointestinal endoscopy显示文摘AIM: To evaluate the effect of posterior lingual lidocaine swab on patient tolerance to esophagogastro-duodenoscopy, the ease of performance of the procedure, and to determine if such use will reduce the need for intravenous sedation. METHODS: Eighty patients undergoing diagnostic esophagogastroduodenoscopy in a tertiary care medical center were randomized to either lidocaine swab or spray. Intravenous meperidine and midazolam were given as needed during the procedure. RESULTS: Patients in the lidocaine swab group (SWG) tolerated the procedure better than those in the spray group (SPG) with a median tolerability score of 2 (1, 4) compared to 4 (2, 5) (P < 0.01). The endoscopists encountered less diffi culty performing the proceduresin the SWG with lower median difficulty scores of 1 (1, 5) compared to 4 (1, 5) in the SPG (P < 0.01). In addition, the need for intravenous sedation was also lower in the SWG compared to the SPG with fewer patients requiring intravenous sedation (13/40 patients vs 38/40 patients, respectively, P < 0.01). The patients in the SWG were more satisfi ed with the mode of local anesthesia they received as compared to the SPG. In addition, the endoscopists were happier with the use of lidocaine swab. CONCLUSION: The use of a posterior lingual lidocaine swab in esophagogastroduodenoscopy improves patient comfort and tolerance and endoscopist satisfaction and decreases the need for intravenous sedation. | Assaad M Soweid Shadi R Yaghi Faek R Jamali Abdallah A Kobeissy Michella E Mallat Rola Hussein Chakib M Ayoub | 2011 | World Journal of Gastroenterology2011，17，47： | 2 |
| 4 | Spontaneous complete regression of hepatic epithelioid haemangioendothelioma显示文摘 | Zaher K Otrock Aghiad Al-Kutoubi Mireille M Kattar Ghazi Zaatari Assaad Soweid | 2006 | Lancet Oncology2006，，5： | 2 |
| 5 | A randomized single-blind trial of whole versus split-dose polyethylene glycol-electrolyte solution for colonoscopy preparation显示文摘 | Amer M.A. El Sayed Zeina A. Kanafani Fadi H. Mourad Assaad M. Soweid Kassem A. Barada Clarisse S. Adorian Walid A. Nasreddine Ala I. Sharara | 2003 | Gastrointestinal Endoscopy2003，，1： | 1 |
| 6 | A randomized single-blind trial of standard diet versus fiber-free diet with polyethylene glycol electrolyte solution for colonoscopy preparation显示文摘 | A. Soweid A. Kobeissy F. Jamali M. El-Tarchichi A. Skoury H. Abdul-Baki L. El-Zahabi A. El-Sayyed K. Barada A. Sharara F. Mourad A. Arabi | 2010 | Endoscopy2010，，08： | 1 |
| 7 | A randomized single- blind trial of standard diet versus fiber-free diet with polyethylene glycol electrolyte solution for colonoscopy preparation 显示文摘 | Soweid AM Kobeissy AA Jamali FR | 2010 | Endoscopy2010，42，8： | 1 |
| 8 | Evaluating the degree of difficulty of laparoscopic colorectal surgery 显示文摘 | Jamali FR Soweid AM Dimassi H | 2008 | Arch Surg2008，143，8： | 1 |
| 9 | Evaluating the degree of difficulty of laparoscopic colorectal surgery显示文摘 | Jamali FR Soweid AM Dimassi H | 2008 | Arch Surg2008，143，8： | 1 |
| 10 | Evaluating the degree of difficulty of laparoscopic colorectal surgery 显示文摘 | Jamali FR Soweid AM Dimassi H | 2008 | Arch Surg2008，143，8： | 1 |
| 11 | Evaluating the degree of difficulty of laparoscopic colorectal surgery 显示文摘 | Jamali FR Soweid AM Dimassi H | 2008 | Arch Surg2008，143，8： | 1 |
| 12 | Changes in health-related attitude and self-reported behaviour of undergraduate students at the American university of Beirut following a health awareness eoume显示文摘 | Afifi Soweid R ElKak F Major S | 2003 | Education Health(Abingdan)2003，16，3： | 1 |
| 13 | Evaluating the degree of difficulty of laparoscopic colorectal surgery显示文摘 | Jamali F R Soweid A M | 2008 | Arch Surg2008，143，8： | 1 |
| 14 | Preoperative anaemia and postoperative outcomes in non-cardiac surgery: a retrospective cohort study显示文摘 | Khaled M Musallam Hani M Tamim Toby Richards Donat R Spahn Frits R Rosendaal Aida Habbal Mohammad Khreiss Fadi S Dahdaleh Kaivan Khavandi Pierre M Sfeir Assaad Soweid Jamal J Hoballah Ali T Taher Faek R Jamali | 2011 | The Lancet2011，，9800： | 1 |
| 15 | An overview of the pathogenesis and natural history of post-transplant T-cell lymphoma显示文摘 | Jamali FR Otrock ZK Soweid AM | 2007 | Leuk Lymphoma2007，48，： | 1 |
| 16 | Spontaneous complete regression of hepatic epithelioid haemangioendothelioma显示文摘 | Zaher K Otrock Aghiad Al-Kutoubi Mireille M Kattar Ghazi Zaatari Assaad Soweid | 2006 | Lancet Oncology2006，，5： | 1 |
| 17 | Catheter probeassisted endoluminal US in inflammatory bowel disease显示文摘 | Chak A KatzJA | 1999 | Gastrointest Endose1999，50，1： | 1 |
| 18 | Prevalence of Endoscopically Identified Heterotopic Gastric Mucosa in the Proximal Esophagus: Endoscopist Dependent?显示文摘 | Cecilio Azar Faek Jamali Hala Tamim Heitham Abdul-Baki Assaad Soweid | 2007 | Journal of Clinical Gastroenterology2007，，5： | 1 |
| 19 | A randomized single-blind trial of whole versus split-dose polyethylene glycol-electrolyte solution for colonoscopy preparation显示文摘 | Amer M.A. El Sayed Zeina A. Kanafani Fadi H. Mourad Assaad M. Soweid Kassem A. Barada Clarisse S. Adorian Walid A. Nasreddine Ala I. Sharara | 2003 | Gastrointestinal Endoscopy2003，，1： | 1 |
| 20 | Plesiomonas shigellaides : an unu- sual cause of diarrhea显示文摘 | Soweid AM Clarkston WK | 1995 | Am J Gastroenterol1995，90，12： | 1 |
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