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| 1 | Reconstruction of chemically burned rat corneal surface by bone marrow-derived human mesenchymal stem cells显示文摘 | Ma Y Xu Y Xiao Z Yang W Zhang C Song E Du Y Li L | 2006 | 中国生物学文摘2006，20，5： | 58 |
| 2 | JAMA子刊:健康生活方式真的可以预防癌症吗?显示文摘根据2016年5月19日发表在国际学术期刊《JAMA Oncology》上的一项最新研究,如果能够遵循良好的生活习惯,包括戒烟,避免酗酒,将BMI维持在正常的18.5到27.5之间,并能够每周适度运动至少150分钟或剧烈运动至少75分钟,美国患癌或死于癌症的白种人中很大一部分人或可避免癌症或癌症死亡的发生。在这项研究中,研究人员对两项针对白种人的研究数据进行了分析, | Song M Giovannucci E | 2016 | 疾病监测2016，31，5： | 12 |
| 3 | Overexpression of blueberry FLOWERING LOCUS T is associated with changes in the expression of phytohormone-related genes in blueberry plants显示文摘Flowering locus T(FT)is a primary integrator in the regulation of plant flowering.Overexpressing a blueberry(Vaccinium corymbosum L.)FT gene(VcFT)(herein VcFT-OX)resulted in early flowering and dwarfing in‘Aurora’plants(herein‘VcFT-Aurora’).In this study,we found that VcFT-OX reduced shoot regeneration from leaf explants.To investigate the potential roles of the phytohormone pathway genes associated with VcFT-OX,differentially expressed(DE)genes in leaf tissues of‘VcFT-Aurora’plants were annotated and analyzed using non-transgenic‘Aurora’plants as a control.Three DE floral genes,including the blueberry SUPPRESSOR of Overexpression of constans 1(VcSOC1)(gibberellin related),Abscisic acid responsive elements-binding factor 2(VcABF2)and protein related to ABI3/VP1(VcABI3/VP1)(ethylene-related),are present under both the phytohormone-responsive and the dwarfing-related Gene Ontology terms.The gene networks of the DE genes overall showed the molecular basis of the multifunctional aspects of VcFT overexpression beyond flowering promotion and suggested that phytohormone changes could be signaling molecules with important roles in the phenotypic changes driven by VcFT-OX. | Xuan Gao Aaron E Walworth Charity Mackie Guo-qing Song | 2016 | Horticulture Research2016，3，1： | 6 |
| 4 | Toxicity of Graphene Quantum Dots in Zebrafish Embryo显示文摘Objective To evaluate the bio-safety of graphene quantum dots(GQDs), we studied its effects on the embryonic development of zebrafish. Methods In vivo, biodistribution and the developmental toxicity of GQDs were investigated in embryonic zebrafish at exposure concentrations ranging from 12.5-200 μg/m L for 4-96 h post-fertilization(hpf). The mortality, hatch rate, malformation, heart rate, GQDs uptake, spontaneous movement, and larval behavior were examined. Results The fluorescence of GQDs was mainly localized in the intestines and heart. As the exposure concentration increased, the hatch and heart rate decreased, accompanied by an increase in mortality. Exposure to a high level of GQDs(200 μg/mL) resulted in various embryonic malformations including pericardial edema, vitelline cyst, bent spine, and bent tail. The spontaneous movement significantly decreased after exposure to GQDs at concentrations of 50, 100, and 200 μg/mL. The larval behavior testing(visible light test) showed that the total swimming distance and speed decreased dose-dependently. Embryos exposed to 12.5 μg/mL showed hyperactivity while exposure to higher concentrations(25, 50, 100, and 200 μg/mL) caused remarkable hypoactivity in the light-dark test. Conclusion Low concentrations of GQDs were relatively non-toxic. However, GQDs disrupt the progression of embryonic development at concentrations exceeding 50 μg/mL. | WANG Zhen Guo ZHOU Rong JIANG Dan SONG Jing E XU Qian SI Jing CHEN Yun Ping ZHOU Xin GAN Lu LI Jian Zhen ZHANG Hong LIU Bin | 2015 | Biomedical and Environmental Sciences2015，28，5： | 6 |
| 5 | A comparison of surgical efficacy between a 1.8-mm microincision and 3.2-mm and 5.5-mm incisions for phacoemulsification显示文摘Phacoemulsification is a commonly used surgical method in cataract surgery. This paper observes and compares the surgical efficacy of three incisions of different length for phacoemulsification to identify the optimal method for cataract surgery. Ninety patients were enrolled in the present study and divided into three groups. The 1.8-mm group received Bausch & Lomb MI60 foldable intraocular lens(IOL) implantation(n=30), 3.2-mm group received Bausch & Lomb Akreos AO foldable lens implantation(n=30), and 5.5-mm group received Alcon TYPE 05 rigid IOL implantation(n=30). Visual acuity, Oculyzer-based anterior segment analysis, and corneal endothelial cell count before surgery, and 3, 7, 30, and 90 d after surgery were recorded and compared. Pseudophakic accommodation three days, one week, one month, and three months after surgery was determined. Intraoperative ultrasound time and ultrasonic energy were recorded. It was finally concluded that for phacoemulsification with the same phaco tip, a 1.8-mm microincision can lead to quicker recovery of visual acuity, more stable astigmatism, and higher pseudophakic accommodation than conventional incision. | E Song Xin Li Ming-Chao Bi Hua Ren Dan Wang Zhi-Hua Cui Wei Yang Hui Shi Ya-Bin Sun | 2018 | International Journal of Ophthalmology(English edition)2018，11，3： | 4 |
| 6 | A Novel Model of Predicting Archie's Cementation Factor from Nuclear Magnetic Resonance(NMR) Logs in Low Permeability Reservoirs显示文摘The resistivity experimental measurements of core samples drilled from low permeability reservoirs of Ordos Basin,Northwest China,illustrate that the cementation factors are not agminate,but vary from 1.335 to 1.749.This leads to a challenge for the estimation of water and hydrocarbon saturation.Based on the analysis of Purcell equation and assumption that rock resistivity is determined by the parallel connection of numerous capillary resistances,a theoretical expression of cementation factor in terms of porosity and permeability is established.Then,cementation factor can be calculated if the parameters of porosity and permeability are determined.In the field application,porosity can be easily obtained by conventional logs.However,it is a tough challenge to estimate permeability due to the strong heterogeneity of low permeability reservoirs.Thus,the Schlumberger Doll Research(SDR)model derived from NMR logs has been proposed to estimate permeability.Based on the analysis of the theoretical expressions of cementation factor and SDR model,a novel cementation factor prediction model,which is relevant to porosity and logarithmic mean of NMR T2spectrum(T2lm),is derived.The advantage of this model is that all the input information can be acquired from NMR logs accurately.In order to confirm the credibility of the novel model,the resistivity and corresponding laboratory NMR measurements of 27 core samples are conducted.The credibility of the model is confirmed by comparing the predicted cementation factors with the core analyzed results.The absolute errors for all core samples are lower than 0.071.Once this model is extended to field application,the accuracy of water and hydrocarbon saturation estimation will be significantly improved. | Liang Wang Zhiqiang Mao Yujiang Shi Qin'e Tao Yumei Cheng Yong Song | 2014 | Journal of Earth Science2014，25，1： | 4 |
| 7 | Development and calibration of the Moon-based EUV camera for Chang'e-3显示文摘The process of development and calibration for the first Moon-based extreme ultraviolet(EUV) camera to observe Earth's plasmasphere is introduced and the design, test and calibration results are presented. The EUV camera is composed of a multilayer film mirror, a thin film filter, a photon-counting imaging detector, a mechanism that can adjust the direction in two dimensions, a protective cover, an electronic unit and a thermal control unit. The center wavelength of the EUV camera is 30.2 nm with a bandwidth of 4.6 nm. The field of view is 14.7° with an angular resolution of 0.08°, and the sensitivity of the camera is 0.11 count s-1Rayleigh-1. The geometric calibration, the absolute photometric calibration and the relative photometric calibration are carried out under different temperatures before launch to obtain a matrix that can correct geometric distortion and a matrix for relative photometric correction,which are used for in-orbit correction of the images to ensure their accuracy. | Bo Chen Ke-Fei Song Zhao-Hui Li Qing-Wen Wu Qi-Liang Ni Xiao-Dong Wang Jin-Jiang Xie Shi-Jie Liu Ling-Ping He Fei He Xiao-Guang Wang Bin Chen Hong-Ji Zhang Xiao-Dong Wang Hai-Feng Wang Xin Zheng Shu-Lin E Yong-Cheng Wang Tao Yu Liang Sun Jin-Ling Wang Zhi Wang Liang Yang Qing-Long Hu Ke Qiao Zhong-Su Wang Xian-Wei Yang Hai-Ming Bao Wen-Guang Liu Zhe Li Ya Chen Yang Gao Hui Sun Wen-Chang Chen | 2014 | Research in Astronomy and Astrophysics2014，14，12： | 4 |
| 8 | Differential expression of meat quality and intramuscular fat deposition related genes in Hanjiang black pigs显示文摘 | Guofang Wu Xin'e Shi Jiping Zhou Lei Wang Yuefeng Li Chengchuang Song Aoqi Xiang Peiyue Dong Shiduo Sun | 2014 | Acta Biochimica et Biophysica Sinica2014，46，12： | 3 |
| 9 | Maize WI5 encodes an endo-1,4-β-xylanase required for secondary cell wall synthesis and water transport in xylem显示文摘Water transport from roots to leaves through xylem is important for plant growth and development.Defects in water transport can cause drought stress,even when there is adequate water in the soil.Here,we identi-fied the maize(Zea mays)wilty5(wi5)mutant,which ex-hibits marked dwarfing and leaf wilting throughout most of its life cycle under normal growth conditions.wilty5 seed-lings exhibited lower xylem conductivity and wilted more rapidly under drought,NaCl,and high temperature treat-ments than wild-type plants.Map-based cloning revealed that WI5 encodes an active endo-1,4-β-xylanase from gly-cosyl dehydration family 10,which mainly functions in degrading and reorganizing cell wall xylan.Reverse-transcription polymerase chain reaction andβ-glucuronidase assays revealed that WI5 is highly expressed in stems,especially in internodes undergoing secondary wall as-sembly.RNA sequencing suggested that WI5 plays a unique role in internode growth.Immunohistochemistry and electron microscopy confirmed that wi5 is defective in xylan deposition and secondary cell wall thickening.Lignin deposition and xylan content were markedly re-duced in wi5 compared to the wild-type plants.Our results suggest that WI5 functions in xylem cell wall thickening through its xylanase activity and thereby regulates xylem water transport,the drought stress response,and plant growth in maize. | Xiaojiao Hu Yang Cui Xiaomin Lu Weibin Song Lei Lei Jinjie Zhu Jinsheng Lai Lizhu E Haiming Zhao | 2020 | Journal of Integrative Plant Biology2020，62，10： | 3 |
| 10 | CCAR1 5' UTR as a natural miRancer of miR-1254 overrides tamoxifen resistance显示文摘 | Gaopeng Li Xiaoli Wu Wenchang Qian Huayong Cai Xinbao Sun Weijie Zhang Sheng Tan Zhengsheng Wu Pengxu Qian Keshuo Ding Xuefei Lu Xiao Zhang Hong Yan Haifeng Song Shouhong Guang Qingfa Wu Peter E Lobie Ge Shan Tao Zhu | 2016 | Cell Research2016，26，6： | 3 |
| 11 | MORN3:MEIG1的分子伴侣在小鼠生精细胞中的表达显示文摘哺乳动物精子发生由细胞发育和分化的精细过程组成。减数分裂基因1(MEG1)在调节精子发生过程中起着重要作用。为探讨MEIGl的作用机制,采用酵母双杂交筛选出可能与MEIG1发生作用的多个蛋白,OJMORN3蛋白。通过制备全长MORN3蛋白N端的特异性多克隆抗体,分别在体外和体内研究MORN3的表达和定位。免疫荧光染色转染CHO细胞显示,MORN3定位在整个包浆。体内实验证实25kDa的MORN3蛋白仅在小鼠睾丸组织中表达,且主要在出生后20天开始表达,即主要表达于精子发生的第三阶段生精细胞变态期。在从成年野生型小鼠分离的混合睾丸细胞的整个生精细胞变态期,MORN3均表达于顶体,在长形精子期该蛋白同时也在精子领表达。在Meig—J基因敲除小鼠中,MORN3总体表达水平和在顶体中的定位没有改变,但在精子领的表达显著降低。以上研究表明MORN3作为MEIGl蛋白的分子伴侣,可能是精子发生过程的另一个重要调节因子。 | Ling Zhang Xue-Jun Shang Hong-Fei Li Yu-Qin Shi Wei Li Maria E Teves Zhi-Qiong Wang Gao-Feng Jiang Shi-Zhen Song Zhi-Bing Zhang | 2015 | Asian Journal of Andrology2015，17，1： | 3 |
| 12 | Tracking of CFSE-labeled endothelial progenitor cells in laser-injured mouse retina显示文摘背景 Endothelial 祖先房间(EPC ) 移植是为 ischemic retinopathy 的有希望的治疗学的策略。当前的学习试图为与 5-(and-6 ) 追踪 EPC 建立一个简单、可靠、荧光灯的标记的方法在伤害激光的老鼠 retina.Methods EPC 的 -carboxyfluorescein diacetate succinimidyl 酉旨(CFSE ) 从人的脐的绳索血 mononuclear 房间被孤立,栽培,并且用 CFSE 的各种各样的集中标记。基于荧光紧张和房间形态学,有在 37 点的 5 mol/L CFSE 的 15 分钟孵化作为最佳的标记条件被选择。幸存能力和标记 CFSE 的 EPC 的 apoptosis 率被染色的 Trypan 蓝色和 Annexin V/PI 染色试金分别地测量。荧光显微镜学被用来在扩大文化时期期间观察标签稳定性。标记的 EPC 被移植进网膜的激光光致疑结伤害的 pigmented 老鼠的玻璃的洞。Evans 蓝 angiography 和完全装的视网膜被检验追踪用 5 mol/L CFSE 介绍了标记的标记的 cells.Results EPC 一块强烈草地荧光和维持的正常形态学没有在在被标记 2 天以后的幸存能力或 apoptosis 率的重要变化, 1 和 4 个星期。荧光紧张逐渐地在 4 个星期的结束在房间减少了。视网膜的 Evans 蓝 angiography 清楚地显示了网膜的毛细作用网络,荧光漏在伤害激光的老鼠模型在 photocoagulated 点附近被观察。在标记的 EPC 的移植以后的一个星期,荧光灯房间在 photocoagulated 损害附近被识别。在移植以后的四个星期,荧光灯像试管的结构在网膜的脉管的 networks.Conclusion EPC 被观察能被 CFSE 在 vitro 标记并且在 vivo 监视了至少 4 个星期,并且参予受伤网膜的容器的修理。 | SHI Hui YANG Wei CUI Zhi-hua LU Cheng-wei LI Xiao-hong LIANG Ling-ling SONG E | 2011 | Chinese Medical Journal2011，，5： | 3 |
| 13 | Paired eye-control study of unilateral opaque bubble layer in femtosecond laser assisted laser in situ keratomileusis显示文摘AIM: To investigate the predictive factors of the opaque bubble layer(OBL) compared to the fellow eye of same patients in FS200 femtosecond laser assisted laser in situ keratomileusis(FS-LASIK).METHODS: This study consisted of 60 consecutive patients(120 eyes) with unilateral OBL during FS-LASIK. Eyes were divided into OBL(the OBL eyes) and OBL-free groups(the fellow eyes) based on the occurrence of OBL. The preoperative demographic data, refraction, keratometry, corneal astigmatism, pachymetry, intraocular pressure and intraoperative data including the outlet location of gas diffusing canal were collected. Conditional logistic regression analysis was performed to find the associated factors with OBL in the two groups by determining odds ratios(OR) and 95%CI.RESULTS: The preoperative demographic data, mean spherical errors, mean K value, suction time, intraocular pressure and central cornea thickness were not significantly different between the two groups. The outlet location of gas diffusing canal(P<0.01, OR 7.16, 95%CI 2.53-20.32) and the corneal astigmatism(P=0.013, OR 0.13, 95%CI 0.03-0.65) were significantly associated with the incidence of OBL by multivariate logistic regression analysis. Visual acuity, efficacy, and safety were comparable between the two groups two months after surgery except for a slightly lower predictability value for the hard OBL eyes.CONCLUSION: The reduction of the incidence of OBL is obvious when the outlet of gas diffusing canal located at the posterior border of the corneoscleral limbus. This is probably consequent to more effectiveness of gas diffusing canal. Corneal astigmatism is also an independent protective factor for OBL formation. | Cheng-Hua Wei Qiao-Yun Dai Li-Xin Mei Yao Ge Peng-Fei Zhang E Song | 2019 | International Journal of Ophthalmology(English edition)2019，12，4： | 2 |
| 14 | Isolation and identifi cation of antimicrobial metabolites from sea anemone-derived fungus Emericella sp.SMA01显示文摘Marine symbiotic fungi represent an intriguing source of discovery of novel secondary metabolites with various biological activities.Sea anemones are benthic marine invertebrates,however,the cultivable symbiotic fungi residing in the sea anemones are paid few attentions compared to those derived from their cnidarian counterparts.Here we show the identification of antimicrobial secondary metabolites from the sea anemone-derived symbiotic fungi.Out offive isolated fungal strains,only the strain SMA01 showed strong antimicrobial activities,which was assigned into the genus Emericella based on the morphological characteristics and the ITS sequencing.Media swift from liquid fermentation to solid rice medium presented little influence on its antibacterial activity.A chemical investigation of the ethyl acetate extract of the Emericella sp.SMA01 led to discovery of the primary antibiotic metabolite phenazine-1-carboxylic acid.The IC_(50) values of the phenazine-1-carboxylic acid against Phytophthora capsici,Gibberella zeae,and Verticillium dahliae were determined to be 23.26-53.89μg/mL.To the best of our knowledge,this was the first report of Emericella sp.in sea anemones.The current study may benefit understanding of the defensive chemical interactions between the symbiotic fungi and their host sea anemones. | Yang YUE Huahua YU Rongfeng LI Linfeng HU Song LIU Rong’e XING Pengcheng LI | 2021 | Journal of Oceanology and Limnology2021，39，3： | 2 |
| 15 | Sirt2 induces C2C12 myoblasts proliferation by activation of the ERK1/2 pathway显示文摘 | Guofang Wu Chengchuang Song Hongzhao Lu Long Jia Gongshe Yang Xin'e Shi Shiduo Sun | 2014 | Acta Biochimica et Biophysica Sinica2014，46，4： | 2 |
| 16 | Rapid phenotypic evolution with shallow genomic differentiation during early stages of high elevation adaptation in Eurasian Tree Sparrows显示文摘Known as the‘third polar region’,the Qinghai-Tibet Plateau represents one of the harshest highland environments in the world and yet a number of organisms thrive there.Previous studies of birds,animals and humans have focused on well-differentiated populations in later stages of phenotypic divergence.The adaptive processes during the initial phase of highland adaptation remain poorly understood.We studied a human commensal,the Eurasian Tree Sparrow,which has followed human agriculture to the Qinghai-Tibet Plateau.Despite strong phenotypic differentiation at multiple levels,in particular in muscle-related phenotypes,highland and lowland populations show shallow genomic divergence and the colonization event occurred within the past few thousand years.In a one-month acclimation experiment investigating phenotypic plasticity,we exposed adult lowland tree sparrows to a hypoxic environment and did not observe muscle changes.Through population genetic analyses,we identified a signature of polygenic adaptation,whereby shifts in allele frequencies are spread across multiple loci,many of which are associated with muscle-related processes.Our results reveal a case of positive selection in which polygenic adaptation appears to drive rapid phenotypic evolution,shedding light on early stages of adaptive evolution to a novel environment. | Yanhua Qu Chunhai Chen Ying Xiong Huishang She Yong E Zhang Yalin Cheng Shane DuBay Dongming Li Per G P Ericson Yan Hao Hongyuan Wang Hongfeng Zhao Gang Song Hailin Zhang Ting Yang Chi Zhang Liping Liang Tianyu Wu Jinyang Zhao Qiang Gao Weiwei Zhai Fumin Lei | 2020 | National Science Review2020，7，1： | 2 |
| 17 | H∞ control of discrete-time linear systems with norm-bounded uncertainties and time delay in state 显示文摘 | Song S H Kim J E | 1998 | Automatica1998，34，1： | 2 |
| 18 | Effect of endothelial progenitor cells derived from human umbilical cord blood on oxygen-induced retinopathy in mice by intravitreal transplantation显示文摘·AIM: To investigate the effect of endothelial progenitor cells(EPCs) labeled by carboxy fluorescein diacetate succinimidyl ester(CFSE) on murine oxygen-induced retinopathy(OIR) by intravitreal transplantation.·METHODS: After isolated from human umbilical cord blood mononuclear cells, EPCs were cultivated and then labeled with CFSE in vitro. C57BL/6J mice were placed to75% hyperoxia chamber from P7 to P12 to establish OIR model. At P12, OIR mice were intravitreally injected with1 μL suspension contained 2×105EPCs(EPCs group) or isometric phosphate buffered saline(PBS group). The contralateral eye of each mice received no injection(OIR group). Evans blue angiography and frozen section were examined to track the labeled cells in OIR group at P15 and P19. Using retina paraffin sections and adenosinediphos phatase staining at P12 and P19, the effect of EPCs on OIR mice was evaluated quantitatively and qualitatively.· RESULTS: The retinas from EPCs group with less non-perfusion area and fewer peripheral tufts wereobserved at P19, comparing with that from PBS or OIR group. The retinopathy in EPCs group receded earlier with less non-ganglion cells and neovascular nuclei,together with relatively regular distribution. The counts of the neovascular nuclei at P19 were reduced by 44% or45%, compared with those of OIR group or PBS group respectively. Three days after EPCs injection, a large number of EPCs appeared in the vitreous cavity and adhered to the retinal surface. While at one week, the cells gathered between the internal plexiform layer and the inner limiting membrane, and some EPCs appeared in retinal vessels.·CONCLUSION: EPCs transplantation can participate in the reparative procedure of the neovascularization in OIR. | Dan Wang Bo Zhang Hui Shi Wei Yang Ming-Chao Bi Xiang-Fu Song Chen Zhang Jian-Hui Cheng Ji-Long Hao E Song | 2016 | International Journal of Ophthalmology(English edition)2016，9，11： | 2 |
| 19 | The opposite prognostic significance of nuclear and cytoplasmic p21 expression in resectable gastric cancer patients显示文摘 | Yefei Huang Weimin Wang Yansu Chen Yulin Huang Jianbing Zhang Song He Yongfei Tan Fulin Qiang Aiping Li Oluf Dimitri R?e Shouyu Wang Yan Zhou Jianwei Zhou | 2014 | Journal of Gastroenterology2014，，11： | 2 |
| 20 | QoS prediction algorithm used in location-aware hybrid Web service显示文摘Quality-of-Service(QoS) describes the non-functional characteristics of Web services. As such, the QoS is a critical parameter in service selection, composition and fault tolerance, and must be accurately determined by some type of QoS prediction method. However, with the dramatic increase in the number of Web services, the prediction failure caused by data sparseness has become a critical challenge. A new ‘hybrid user-location-aware prediction based on weighted Adamic-Adar(WAA)'(HUWAA) was proposed. The implicit neighbor search was optimized by incorporating location factors. Meanwhile, the ability of the improved algorithms to solve the data sparsity problem was validated in experiments on public real world datasets. The new algorithm outperforms the existing of item-based pearson correlation coefficient(IPCC), user-based pearson correlation coefficient(UPCC) and Web service recommender system(WSRec) algorithms. | E Haihong Tong Junjie Song Meina Song Junde | 2015 | The Journal of China Universities of Posts and Telecommunications2015，22，1： | 2 |
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