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| 1 | Clinical and prognostic implications of delirium in elderly patients with non–ST-segment elevation acute coronary syndromes显示文摘Background Elderly patients with non-ST-segment elevation acute coronary syndromes(NSTE-ACS)may present delirium but its clinical relevance is unknown.This study aimed at detennining the clinical associated factors,and prognostic implications of delirium in old-aged patients admitted for NSTE-ACS.Methods LONGEVO-SCA is a prospective multicenter registry including unselected patients with NSTE-ACS aged>80 years.Clinical variables and a complete geriatric evaluation were assessed during hospitalization.The association between delirium and 6-month mortality was assessed by a Cox regression model weighted for a propensity score including the potential confounding variables.We also analysed its association with 6-month bleeding and cognitive or functional decline.Results Among 527 patients included,thirty-seven(7%)patients presented delirium during the hospitalization.Delirium was more frequent in patients with dementia or depression and in those from nursing homes(27.0%vs.3.1%,24.3%vs.11.6%,and 11.1%V5.2.2%,respectively;all P<0.05).Delirium was significantly associated with in-hospital infections(27.0%vs.5.3%,P<0.001)and usage of diuretics(70.3%vs.49.8%,P=0.02).Patients with delirium had longer hospitalizations[median 8.5(5.5-14)vs.6.0(4.0-10)days,P=0.02]and higher incidence of 6-month bleeding and mortality(32.3%vs.10.0%and 24.3%vs.10.8%,respectively;both P<0.05)but similar cognitive or functional decline.Delirium was independently associated with 6-month mortality(HR=1.47,95%CI:1.02-2.13,P=0.04)and 6-month bleeding events(OR=2.87;95%CI:1.98-4」6,P<0.01).Conclusions In-hospital delirium in elderly patients with NSTE-ACS is associated with some preventable risk factors and it is an independent predictor of 6-month mortality. | Miquel Vives-Borras Manuel Martinez-Selles Albert Ariza-Sole Maria T.Vidan Francesc Formiga Hector Bueno Juan Sanchis Oriol Alegre Albert Duran-Cambra Ramon Lopez-Palop Emad Abu-Assi Alessandro Sionis LONGEVO-SCA Investigators | 2019 | Journal of Geriatric Cardiology2019，16，2： | 3 |
| 2 | Severe aortic regurgitation and reduced left ventricular ejection fraction: Outcomes after isolated aortic valve replacement and combined surgery显示文摘 | Alessandro Sionis Ana García-Alvarez María ángeles Castel Marco Cordero Miguel Josa Félix Pérez-Villa Eulàlia Roig | 2010 | Journal of Heart and Lung Transplantation2010，，4： | 1 |
| 3 | Effects of cyclosporine, tacrolimus and sirolimus on vascular changes related to immune response显示文摘 | Rigol M Solanes N Sionis A Galvez C Martorell J Rojo I | 2008 | J Heart Lung Transplant2008，27，： | 1 |
| 4 | Sialoendoscopy with and without holmium:YAG laser-assisted lithotripsy in the manage- ment of obstructive sialadenitis of major salivary glands显示文摘 | Sionis S Caria RA Trucas M | 2014 | Br J Oral Maxillofac Surg2014，52，1： | 1 |
| 5 | Value of the implantable loop recover for the management ofpatients with unexplained syncot显示文摘 | Boersma L Mont L Sionis A | 2004 | Europace2004，6，1： | 1 |
| 6 | Formulaic speech in the L2 class- room: An attempt at identification and classification 显示文摘 | Girard M Sionis C | 2003 | Pragrnatics2003，，13： | 1 |
| 7 | Lumbar disc heights after extent fixation and anterior interbody fusion:a prospective 2-year follow-up of clinical and radiogrpaphic results显示文摘 | Sioni J | 1994 | Spinal Disord1994，7，6： | 1 |
| 8 | Development in intracoronary stents显示文摘 | Stefanidis IK Tolls VA Sionis DG et al | 2002 | Hellenic J Cardiol2002，43，： | 1 |
| 9 | Biochemical detection of systolic dysfunction显示文摘 | Sionis A Bosch X | 1998 | Lancet1998，351，9108： | 1 |
| 10 | Hypoxia induces B-type natriuretic peptide release in cell lines derived from human cardiomyocytes显示文摘 | Casals G Ros J Sionis A | 2009 | Am J Physiol Heart Circ Physiol2009，297，2： | 1 |
| 11 | Low troponin-l levels on admi-ssion are associtaed with worse prognosis in patients with fulminantmyocardifis显示文摘 | Freixa X Sionis A Castd A et a1 | 2009 | Transplant Proc2009，41，6： | 1 |
| 12 | Hypoxia induces B-type natriuretic peptide release in cell lines derived from human cardiomyocytes显示文摘 | Casals G Ros J Sionis A | 2009 | Am J Physiol Heart Cite Physiol2009，297，2： | 1 |
| 13 | Biochemical detection of systolic dysfunction 显示文摘 | Sionis A Bosch X | 1998 | Lancet1998，351，9108： | 1 |
| 14 | Robotic left ventricular epicardial lead positioning显示文摘 | Loddo P Sionis C Schintu B | 2015 | Muhimed Man Cardiothorac Surg2015，5，： | 1 |
| 15 | Sialoendoscopy with and without holmium: YAG laser-assisted lithotripsy in the man- agement of obstructive sialadenitis of major salivary glands 显示文摘 | Sionis S Curia RA Trucas M | 2014 | Br J Oral Maxillofac Surg2014，52，1： | 1 |
| 16 | Hypoxia induces B-type natriuretic peptide release in cell lines derived from human cardiomyocytes显示文摘 | Casals G Ros J Sionis A | 2009 | Am J Physiol Heart Circ Physiol2009，297，2： | 1 |
| 17 | Hypoxia induces B-type natriuretic peptide release in cell lines derived from human cardiomyocytes显示文摘 | Casals G Ros J Sionis A | 2009 | Am J Physiol Heart Circ Physiol2009，297，2： | 1 |
| 18 | Sialoendoscopy with and without holmium:YAG laser-assisted lithotripsy in the management of obstructive sialadenitis of major salivary glands显示文摘 | Sionis S Caria R A Trucas M | 2014 | Br J Oral Maxillofac Surg2014，52，1： | 1 |
| 19 | En- hanced contact endoscopy for the detection of neoan- giogenesis in tumors of the larynx and hypopharynx 显示文摘 | PUXEDDU R SIONIS S GEROSA C | 2015 | Laryngoscope2015，125，： | 1 |
| 20 | Low Troponin-I Levels on Admission Are Associated With Worse Prognosis in Patients With Fulminant Myocarditis显示文摘 | X. Freixa A. Sionis á. Castel E. Guasch P. Loma-Osorio D. Arzamendi E. Roig F. Perez-Villa | 2009 | Transplantation Proceedings2009，，6： | 1 |
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