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| 1 | 大鼠消化道应激时中枢神经系统FOS蛋白的表达显示文摘目的研究消化道应激状态时中枢神经系统的变化。方法应用SD大鼠结肠内手术埋管,注射三硝基苯碘酸(TNBS)造成应激反应。用免疫组化的方法观察神经细胞FOS核蛋白的表达。结果下丘脑室旁核、脑干孤束核、脑桥臂旁核、蓝斑核、腰骶髓的后角、结肠壁的肠肌丛和粘膜下丛神经元中有大量FOS核蛋白的出现。结论消化道和中枢神经系统在应激状态中有密切联系。 | 夏蓉 Sinniger V | 1999 | 上海第二医科大学学报1999，19，6： | 6 |
| 2 | Observation of an α-synuclein liquid droplet state and its maturation into Lewy body-like assemblies显示文摘Misfoldedα-synudein is a major component of Lewy bodies,which are a hallmark of Parkinson's disease(PD).A large body of evidence shows thatα-synuclein can aggregate into amyloid fibrils,but the relationship between a-synuclein self-assembly and Lewy body formation remains unclear.Here,we show,both in vitro and in a Caenorhabditis elegans model of PD,thatα-synuclein undergoes liquid-liquid phase separation by forming a liquid droplet state,which converts into an amyloid-rich hydrogel with Lewy-body-like properties.This maturation process towards the amyloid state is delayed in the presence of model synaptic vesicles in vitro.Taken together,these results suggest that the formation of Lewy bodies may be linked to the arrested maturation ofα-synuclein condensates in the presence of lipids and other cellular components. | Maarten C.Hardenberg Tessa Sinnige Sam Casford Samuel T.Dada Chetan Poudel Elizabeth A.Robinson Monika Fuxreiter Clemens F.Kaminksi Gabriele S.Kaminski Schierle Ellen A.A.Nollen Christopher M.Dobson Michele Vendruscolo | 2021 | Journal of Molecular Cell Biology2021，13，4： | 3 |
| 3 | Mitochondrial genome of savalia savaglia (cnidaria, hexacorallia) and early metazoan phylogeny显示文摘 | SINNIGER F CHEVALDONNE' P PAWLOWSKI J | 2007 | J of Molecular Evolution2007，64，： | 1 |
| 4 | The prevalence of disease clusters in older adults with multiple chronic diseases-a systematic literature review显示文摘 | Sinnige J Braspenning J Schellevis F | 2013 | PLoS One2013，8，79： | 1 |
| 5 | The barley two-pore K^+-channd HvKCO1 interacts with 14-3-3 proteins in an isoform specific manner显示文摘 | Sinnige M P Hcopen P Wijngaard J P Rcobeek I | 2005 | Plant Science2005，169，： | 1 |
| 6 | Quantitative structure-activity relationships for the toxicity and bioconcentration factor of nitrobenzene derivatives towards the guppy (Poecilia reticulata)显示文摘 | Deneer J Sinnige T Seinen W | 1987 | Aquatic toxicology1987，10，2： | 1 |
| 7 | 14-3-3 adaptor proteins are intermediates in ABA signal transduction during barley seed germination显示文摘 | Schoonheim P J Sinnige M P Casaretto J A | 2007 | The Plant Journal2007，49，2： | 1 |
| 8 | The recombinase IntA is required for exicision of esp-containing ICEE fml in Enterococcus faecium显示文摘 | Top J Sinnige J C Majoor E A M | 2011 | J Bacteriol2011，，： | 1 |
| 9 | 14- 3-3 adaptor proteins are intermediates in ABA signal transduction during barley seed germination 显示文摘 | Schoonheim P J Sinnige M P Casaretto J A | 2007 | Plant J2007，49，： | 1 |
| 10 | Active armor protec- tion---conception and design of steerable launcher systems fed by modular pulsed-power supply units显示文摘 | Sterzelmeier K Brommer V Sinniger L | 2001 | IEEE Transactions on Magnet- ics2001，37，1： | 1 |
| 11 | Analysis of freely dissolved alcohol ethoxylate homo- logues in various seawater matrixes using solid-phase microextraction显示文摘 | DROGE S T J SINNIGE T L HERMENS J L M | 2007 | Anal Chem2007，，28： | 1 |
| 12 | Active armor protection-conception and design of steerable launcher systems fed by modular pulsed-power supply units显示文摘 | Klaus Sterzelmeier Volker Brommer Laurent Sinniger | 2001 | IEEE Trans on Magnetics2001，37，1： | 1 |
| 13 | Active armor protection-conception and design of steerable launehcr systems fed by modular pulsed-power supply units显示文摘 | Klaus Sterzelmeier Volker Brommer Laurent Sinniger | | 0，，01： | 1 |
| 14 | Vagus nerve stimulation : from epilepsy to the cholinergic anti-inflammatory pathway 显示文摘 | Bonaz B Picq C Sinniger V | 2013 | Neurogastroenterol Moti12013，25，3： | 1 |
| 15 | 14-3-3 adaptor proteins are intermediates in ABA signal transduction during barley seed germination显示文摘 | Schoonheim PJ Sinnige MP Casaretto JA | | 0，，02： | 1 |
| 16 | c-fos and CRF receptor gene transcription in the brain of acetic acid-induced somato-visceral pain in rats显示文摘 | Sinniger V Porcher C Mouchet P | 2004 | Pain2004，110，3： | 1 |
| 17 | Abbscisic acid and 14-3-3 proteins control K+ channel activity in barley embryonic root显示文摘 | Wijngaard P W Sinnige M P Roobeek I Reumer A Schoonheim P J Mol J N M Wang M De Boer A H | | 0，，： | 1 |
| 18 | c-fos and CRF receptor gene transcription in the brain of acetic acid-induced somato-visceral pain in rat显示文摘 | Sinniger V Porcher C Mouchet P | 2004 | Pain2004，110，3： | 1 |
| 19 | Fedotozine,a kappa-opioid agonist,prevents spinal and supra-spinal Fos expression induced by a noxious visceral stimulus in the rat显示文摘 | Bonaz B Rivière PJ Sinniger V | 2000 | Neurogastroenterol Motil2000，12，： | 1 |
| 20 | Active armor protection-conception and design of steerable launcher systems fed by modular pulsed-power supply units显示文摘 | STERZELMEIER K BROMMER V SINNIGER L | 2001 | IEEE Transactions on Magnetics2001，37，1： | 1 |
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