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| 1 | 非洲裔美国人体力活动与高血压发生的相关性显示文摘非洲裔美国人在美国各种族(民族)中高血压患病率(男性为40.8%,女性为41.5%)最高。有证据表明,与美国其他种族(民族)相比,非洲裔美国人高血压与因心肌梗死、脑卒中和终末期肾脏疾病引起的过早功能丧失和死亡呈不成比例地升高相关。需要确定控制非洲裔美国人危险因素的措施,以减轻其发生高血压的风险。在许多其他人群中已证实,体力活动对预防高血压有保护作用。因此,高血压指南推荐采用体力活动作为预防性生活行为方式。 | Diaz KM Booth JN 3rd Seals SR Abdalla M Dubbert PM Sims M Ladapo JA Redmond N Muntner P Shimbo D | 2017 | 中华高血压杂志2017，25，2： | 10 |
| 2 | 术中应用荧光素钠有利于胶质母细胞瘤浸润边缘的手术切除(英文)显示文摘Objective Extent of resection is an important prognostic factor in patients undergoing surgery for glioblastoma( GBM).Recent evidence suggests that intravenously administered fluorescein sodium associates with tumor tissue,facilitating safe maximal resection of GBM. In this study,the authors evaluate the safety and utility of intraoperative fluorescein guidance for the prediction of histopathological alteration both in the contrast-enhancing( CE) regions,where this relationship has been established,and into the nonCE( NCE),diffusely infiltrated margins. Methods Thirty-two patients received fluorescein sodium( 3 mg/kg) intravenously prior to resection. Fluorescence was intraoperatively visualized using a Zeiss Pentero surgical microscope equipped with a YELLOW 560 filter.Stereotactically localized biopsy specimens were acquired from CE and NCE regions based on preoperative MRI in conjunction with neuronavigation. The fluorescence intensity of these specimens was subjectively classified in real time with subsequent quantitative image analysis,histopathological evaluation of localized biopsy specimens,and radiological volumetric assessment of the extent of resection.Results Bright fluorescence was observed in all GBMs and localized to the CE regions and portions of the NCE margins of the tumors,thus serving as a visual guide during resection. Gross-total resection( GTR) was achieved in 84% of the patients with an average resected volume of 95%,and this rate was higher among patients for whom GTR was the surgical goal( GTR achieved in 93. 1% of patients,average resected volume of 99. 7%). Intraoperative fluorescein staining correlated with histopathological alteration in both CE and NCE regions,with positive predictive values by subjective fluorescence evaluation greater than 96% in NCE regions. Conclusions Intraoperative administration of fluorescein provides an easily visualized marker for glioma pathology in both CE and NCE regions of GBM. These findingssupport the use of fluorescein as a microsurgical adjunct for guiding GBM resection to facilitate safe maximal removal. | Neira JA Ung TH Sims J Malone HR Chow DS Samanamud JL Zanazzi GJ Guo X Bowden SG Zhao B Sheth SA McKhann GM 2nd Sisti MB Canoll P D'Amico RS Bruce JN | 2016 | 中华神经外科疾病研究杂志2016，15，5： | 2 |
| 3 | The impact of glycosyla- tion on the biological function and structure of human immuno- globulins显示文摘 | Arnold JN Wormald MR Sim RB | 2007 | Annu Rev Immunol2007，25，： | 1 |
| 4 | The impact of glycosylation on the biological function and structure of human im- munoglobulins显示文摘 | ARNOLD JN WORMALD MR SIM RB | 2007 | Annu Rev Immunol2007，，25： | 1 |
| 5 | Di-ethylhexylphthalate(DEHP) modulates cell invasion,migration and anchorage independent growth through targeting S100P in LN-229 glioblastoma cells显示文摘 | Sims JN Graham B Pacurari M | 2014 | Int J Environ Res Public Health2014，11，5： | 1 |
| 6 | The impact of glycosy- lation on the biological function and structure of human immuno- globulins 显示文摘 | Arnold JN Wormald MR Sim RB | 2007 | Annu Rev Immunol2007，25，： | 1 |
| 7 | An overview of second generation biofuel technologies 显示文摘 | Sims RE Mabee W Saddler JN | 2010 | Bioresource Technology2010，101，： | 1 |
| 8 | Three-year prospective validation of a pre-endoscopic risk stratification in patients with acute upper-gastrointestinal haemorrhage显示文摘 | Cameron EA Pratap JN Sims TJ | 2002 | Eur J Gastroenterol Hepatol2002，14，： | 1 |
| 9 | Mannan binding lectin and its interaction with immunoglobulins in health and in disease 显示文摘 | Arnold JN Dwek RA Rudd PM Sim RB | 2006 | Immunol Lett2006，106，2： | 1 |
| 10 | Visual analytics of sur-veillance data on foodborne vibriosis,United States,1973-2010显示文摘 | Sims JN Isokpehi RD Cooper GA | | 0，，01： | 1 |
| 11 | Visual analytics of surveillance data on foodborne vibriosis, United States, 1973- 2010 显示文摘 | Sims JN Isokpehi RD Cooper GA | 2011 | Environ Health Insights2011，，5： | 1 |
| 12 | Visual analytics of surveil- lance data on foodbome vibriosis, United States, 1973 - 2010 显示文摘 | Sims JN Isokpehi RD Cooper GA | 2011 | Environ Health Insights2011，5，： | 1 |
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