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| 1 | Music in depression: Neural correlates of emotional experience in remitted depression显示文摘AIM: To investigate neural and behavioral correlates of emotional experiences as potential vulnerability markers in remitted depression. METHODS: Fourteen remitted participants with a history of major depression and fourteen closely matched healthy control participants took part in the study. We used two psychiatric interviews(Hamilton Depression Rating Scale, Montgomery-Asberg Depression Rating Scale) and one self-report scale(Beck Depression Inventory) to assess remission. Healthy control participants were interviewed by an experienced psychiatrist to exclude those who showed any current or lifetime psychiatric or neurological disorders. To explore psychosocialand cognitive-interpersonal underpinnings of potential vulnerability markers of depression, early life stress, coping styles and alexithymia were also assessed. We induced pleasant and unpleasant emotional states using congruent combinations of music and human emotional faces to investigate neural and behavioral correlates of emotional experiences; neutral stimuli were used as a control condition. Brain responses were recorded using functional magnetic resonance imaging. Behavioral responses of pleasantness, arousal, joy and fear were measured via button-press inside the resonance imaging scanner. RESULTS: The mean age of the sample was 54.9(± 11.3) years. There were no differences between remitted depressed(RD)(n = 14; 9 females and 5 males) and healthy participants(n = 14; 8 females and 6 males) regarding age, current degree of depression, early life stress, coping styles and alexithymia. On a neural level, RD participants showed reduced activations in the pregenual anterior cingulate cortex(pg ACC) in response to pleasant [parameter estimates:-0.78 vs 0.32; t(26) =-3.41, P < 0.05] and unpleasant [parameter estimates:-0.88 vs 0.56; t(26)=-4.02, P < 0.05] emotional stimuli. Linear regression analysis revealed that pg ACC activity was modulated by early life stress [β =-0.48; R2 = 0.23, F(1,27) = 7.83, P < 0.01] and taskoriented coping style [β = 0.63; R2 = 0.37, F(1,27) = 16.91, P < 0.001]. Trait anxiety modulated hippocampal responses to unpleasant stimuli [β = 0.62; R2= 0.38, F(1,27) = 15.95, P < 0.001]. Interestingly, in their reported experiences of pleasantness, arousal, happiness and fear in response to pleasant, unpleasant and neutral stimuli, RD participants did not differ significantly from healthy control participants. Adding trait anxiety or alexithymia as a covariate did not change the results.CONCLUSION: The present study indicates that, in euthymic individuals, depression history alters neural correlates, but not the subjective dimension of pleasant and unpleasant emotional experiences. | Sabine Aust Karin Filip Stefan Koelsch Simone Grimm Malek Bajbouj | 2013 | World Journal of Psychiatry2013，3，2： | 3 |
| 2 | Characteriza- tion of doped tin dioxide anodes prepared by a sol + gel technique and their application in an SPE-reactor显示文摘 | Grimm J H BDG Simon U Sanderson R D | 2000 | Journal of Applied Electrochemistry2000，30，： | 1 |
| 3 | Effect of routine repeat tran-surethral resection for superficial bladder cancer:a long-term obser-vational study显示文摘 | Grimm MO Steinhoff C Simon X | | 0，，2： | 1 |
| 4 | Effect of routine repeat transurethral resection for superficial bladder cancer:a long-term observational study显示文摘 | Grimm MO Steinhoff C Simon X | | 0，，2： | 1 |
| 5 | Effect of Routine Repeat Transurethral Resection for Superficial Bladder Cancer: A Long-term Observational Study显示文摘 | MARC-OLIVER GRIMM CHRISTINE STEINHOFF XENIA SIMON PHILIPP SPIEGELHALDER ROLF ACKERMANN THOMAS ALEXANDER V?GELI | 2003 | The Journal of Urology2003，，2： | 1 |
| 6 | Effect of routinerepeat transurethral resection for superficial bladder cancer:a long-term observational study 显示文摘 | Grimm MO Steinhoff C Simon X | 2003 | J Urol2003，170，2： | 1 |
| 7 | Characterization of doped tin dioxide anodes prepared by a sol-gel technique and their application in an SPE-reactor显示文摘 | Grimm J H Bessarabov D G Simon U | 2000 | J Appl Elec2000，30，3： | 1 |
| 8 | Characterization of doped tin dioxide anodes prepared by a sol-gel technique and their application in an SPE-reactor显示文摘 | Grimm J H Bessarabov D G Simon U | 2000 | Journal of Applied Electrochemistry2000，30，3： | 1 |
| 9 | Muhimarket contact resource dissimilarity: A competitive dynamics perspective 显示文摘 | Young G Smith K G Grimm C M Simon D | 2000 | Journal of Management2000，26，： | 1 |
| 10 | Characterization of doped tin dioxide anodes prepared by a sol-gel technique and their application in an SPE-reactor显示文摘 | Grimm J H Simon U Sanderson R D | 2000 | Journal of Applied Electrochemistry2000，30，3： | 1 |
| 11 | Effect of routine repeat transurethral resection for superficial bladder cancer:a long-term observational study显示文摘 | Grimm MO Steinhoff C Simon X | 2003 | Uorl2003，170，： | 1 |
| 12 | Characterization of doped tin dioxide anodes prepared by a sol-gel technique and their application in an SPE-reactor 显示文摘 | Grimm J H Bessarabov D G Simon U | 2000 | Journal of Applied Electrochemistry2000，30，3： | 1 |
| 13 | Effect of routine repeat transurethral resection for superficial bladder canc- er:a long-term observational study显示文摘 | Grimm MO Steinhoff C Simon X | 2003 | J Urol2003，170，21： | 1 |
| 14 | Effect of routine repeat TUR for superficial bladder cancer:a long-term observational study显示文摘 | Grimm MO Steinhoff C Simon X | 2003 | J Urol2003，170，21： | 1 |
| 15 | Effect of routine repeat transurethral resection for superficial bladder cancer:a long-term observation study显示文摘 | Grimm MO Steinhoff C Simon X | 2003 | J Urol2003，170，21： | 1 |
| 16 | Multimarket Contact and Resource Dissimilarity:A Competitive Dynamics Perspective显示文摘 | Young G Smith K G Grimm C M Simon D | 2000 | Journal of Management2000，26，： | 1 |
| 17 | Effect of routine repeat tran- surethral resection for superficial bladder cancer:A long-term observa- tional study 显示文摘 | Grimm MO Steinhoff C Simon X | 2003 | J Urol2003，170，21： | 1 |
| 18 | Effect of routine repeat transurethral resection for superficial bladder cancer: a long-term observational study显示文摘 | Grimm MO Steinhoff C Simon X | 2003 | J Urol2003，170，21： | 1 |
| 19 | Effect of routine repeat transurethral resection for superficial bladder cancer:a long-term observational study显示文摘 | GRIMM M O STEINHOFF C SIMON X | 2003 | J Urol2003，170，2： | 1 |
| 20 | Effeet of routine repeat transurethral resection for super ficialbl add erc Kncer: a long显示文摘 | Grimm M Steinho C Simon X | 2009 | J Uwl2009，170，2： | 1 |
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