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您的检索式：作者名="Simon Michael Fitzgerald"
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| 1 | 贫血对高龄女性认知功能的影响显示文摘目的分析我国长寿地区90岁以上老年女性贫血对其认知功能的影响。方法利用2008—2009年中国老年人口健康影响因素跟踪调查(CLHLS)项目研究数据,包括5个长寿地区的90岁以上老年女性383名。使用简易精神状况检查法(MMSE)量表收集研究对象认知功能信息,进行医学体格检查,测定血红蛋白等血生化指标。分析贫血组和非贫血组老人认知功能的差异,采用非条件logistic回归分析贫血对老年女性认知功能的影响。结果在383名研究对象中,贫血组141例,非贫血组242名;贫血组认知功能评分为(9.65±9.32)分,非贫血组为(13.06±10.25)分(X^2=5.59,P〈0.05);贫血组认知功能较差的比率为84.4%(119/141),非贫血组为72.3%(175/242)(X^2=8.08,P〈0.05)。多因素分析显示,在调整年龄、文化程度、婚姻状况、吸烟和饮酒后,贫血组发生认知功能受损的风险约是非贫血组的2倍(OR=2.016,95%口:1.185-3.431,P=0.010)。结论贫血会增加我国长寿地区高龄女性认知功能受损的发生风险。 | 翟屹 施小明 钱汉竹 Simon Michael Fitzgerald 曾毅 殷召雪 徐建伟 柳玉芝 | 2011 | 中华预防医学杂志2011，45，9： | 6 |
| 2 | High Sensitivity C-Reactive Protein Associated with Different Health Predictors in Middle-Aged and oldest old Chinese显示文摘Objective To describe the distribu on of plasma high sensi vity C-reac ve protein (hsCRP) and explore the rela onship between hsCRP and metabolic risk factors among residents living in longevity areas of China.Methods 268 individuals aged between 40 and 59 years and 506 individuals aged over 90 years were selected from 5 longevity areas of China to par cipate in a cross sec on longitudinal cohort study.The par cipants were interviewed with general health related ques onnaire to collect their demographic,behavioral and lifestyle data,as well as their chronic condi ons,and meanwhile their physical and biomedical parameters including waist circumference (WC),blood pressure (BP),hsCRP,plasma lipids,and fas ng blood glucose (FBG) were measured.Results The median of hsCRP was 0.99 mg/L in the middle-aged group and 1.76 mg/L in the oldest old group.No significant gender difference was observed between the above two groups.Among the oldest old individuals,36.56% had an hsCRP level >3.0 mg/L.The prevalence of high hsCRP was 16.79% in the middle-aged group.The results of stepwise mul ple linear regression analyses showed that HDL-C was independently associated with ln (hsCRP) concentra on in the middle-aged group,whereas ln (TG),HDL-C and FBG were correlated a er adjustment for gender,study site,smoking,drinking,educa on and BMI in the oldest old group.Conclusion HDL-C is a stronger predictor of elevated hsCRP than other metabolic factors in the middle-aged popula on.For the oldest old persons,high TG,low HDL-C,and FBG predict elevated plasma hsCRP. | ZHAI Yi SHI Xiao Ming FITZGERALD Simon Michael QIAN Han Zhu KRAUS Virginia B SERENY Melanie HU Perry YIN Zhao Xue XU Jian Wei ZENG Yi | 2012 | Biomedical and Environmental Sciences2012，25，3： | 0 |
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