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| 1 | Endoscopic ultrasound-guided choledochoduodenostomy in patients with failed endoscopic retrograde cholangiopancreatography显示文摘Endoscopic ultrasonography (EUS)-guided biliary drainage was performed for treatment of patients who have obstructive jaundice in cases of failed endoscopic retrograde cholangiopancreatography (ERCP). In the present study,we introduced the feasibility and outcome of EUS-guided choledochoduodenostomy in four patients who failed in ERCP. We performed the procedure in 2 papilla of Vater,including one resectable case,and 2 cases of cancer of the head of pancreas. Using a curved linear array echoendoscope,a 19 G needle or a needle knife was punctured transduodenally into the bile duct under EUS visualization. Using a biliary catheter for dilation,or papillary balloon dilator,a 7-Fr plastic stent was inserted through the choledochoduodenostomy site into the extrahepatic bile duct. In 3 (75%) of 4 cases,an indwelling plastic stent was placed,and in one case in which the stent could not be advanced into the bile duct,a naso-biliary drainage tube was placed instead. In all cases,the obstructive jaundice rapidly improved after the procedure. Focal peritonitis and bleeding not requiring blood transfusion was seen in one case. In this case,pancreatoduodenectomy was performed and the surgical findings revealed severe adhesion around the choledochoduodenostomy site. Although further studies and development of devices are mandatory,EUS-guided choledochoduodenostomy appears to be an effective alternative to ERCP in selected cases. | Takao Itoi Fumihide Itokawa Atsushi Sofuni Toshio Kurihara Takayoshi Tsuchiya Kentaro Ishii Shujiro Tsuji Nobuhito Ikeuchi Fuminori Moriyasu | 2008 | World Journal of Gastroenterology2008，14，39： | 13 |
| 2 | Prognosis of cancer with branch duct type IPMN of the pancreas显示文摘AIM:To examine the coexistence of metachronous and synchronous cancer in branch duct intraductal papillary mucinous neoplasms of the pancreas (IPMN).METHODS: We reviewed the records of 145 patients with branch duct IPMN between January 1991 and April 2008 and assessed the relationship between IPMN and intraor extra-pancreatic carcinoma and the outcome of IPMN.RESULTS: The mean observation period was 55.9 ± 45.3 mo. Among the 145 patients, the frequency of extra-pancreatic cancer was 29.0%. The frequency of gastric cancer, colon cancer, breast cancer, and pan-creatic cancer were 25.5%, 15.7%, 13.7%, and 9.8%, respectively. Twenty (13.8%) of the patients died. The cause of death was extra-pancreatic carcinoma in 40%,pancreatic cancer in 25%, IPMN per se in 20%, and benign disease in 15% of the patients.CONCLUSION: The prognosis for IPMN depends not on the IPMN per se, but on the presence of intraor extra-pancreatic cancer. | Nobuhito Ikeuchi Takao Itoi Atsushi Sofuni Fumihide Itokawa Takayoshi Tsuchiya Toshio Kurihara Kentaro Ishii Shujiro Tsuji Junko Umeda Fuminori Moriyasu Akihiko Tsuchida Kazuhiko Kasuya | 2010 | World Journal of Gastroenterology2010，16，15： | 3 |
| 3 | Endoscopic ultrasound‐guided choledochoantrostomy as an alternative extrahepatic bile duct drainage method in pancreatic cancer with duodenal invasion显示文摘 | Takao Itoi Fumihide Itokawa Takayoshi Tsuchiya Shujiro Tsuji Ryosuke Tonozuka | 2013 | Digestive Endoscopy2013，，： | 2 |
| 4 | Clinical evaluation of a novel lumen-apposing metal stent for endosonography-guided pancreatic pseudocyst and gallbladder drainage (with videos)显示文摘 | Takao Itoi Kenneth F. Binmoeller Janak Shah Atsushi Sofuni Fumihide Itokawa Toshio Kurihara Takayoshi Tsuchiya Kentaro Ishii Shujiro Tsuji Nobuhito Ikeuchi Fuminori Moriyasu | 2012 | Gastrointestinal Endoscopy2012，，4： | 2 |
| 5 | Endoscopic ultrasonography-guided biliary drainage显示文摘 | Takao Itoi Atsushi Sofuni Fumihide Itokawa Takayoshi Tsuchiya Toshio Kurihara Kentaro Ishii Shujiro Tsuji Nobuhito Ikeuchi Junko Umeda Fuminori Moriyasu Akihiko Tsuchida | 2010 | Journal of Hepato-Biliary-Pancreatic Sciences2010，，5： | 2 |
| 6 | New large-diameter balloon-equipped sphincterotome for removal of large bile duct stones (with videos)显示文摘 | Takao Itoi Atsushi Sofuni Fumihide Itokawa Toshio Kurihara Takayoshi Tsuchiya Kentaro Ishii Shujiro Tsuji Nobuhito Ikeuchi Junko Umeda Fuminori Moriyasu | 2010 | Gastrointestinal Endoscopy2010，，4： | 2 |
| 7 | Transnasal endoscopic biliary drainage as a rescue management for the treatment of acute cholangitis显示文摘Endoscopic biliary drainage has been established to provide effective treatment for acute obstructive jaundice and cholangitis. A recently developed ultrathin transnasal videoendoscope (TNE) is minimally invasive even for critically ill patients and can be performed without conscious sedation. Transnasal endoscopic biliary drainage (TNE-BD) is performed using a frontviewing TNE with approximately 5 mm outer diameter and 2 mm working channel diameter. Finally, 5F nasobiliary tube or plastic stent are placed. Technical success rates are approximately 100% and 70% for postendoscopic sphincterotomy or placement of self-expandable metallic stent, and intact papilla, respectively. There are no serious complications. In conclusion, although further cases should be accumulated, TNEBD and in particular, one-step naso-biliary drainage using TNE may be a useful and novel technique for the treatment of acute cholangitis. | Takao Itoi Atushi Sofuni Fumihide Itokawa Takayoshi Tsuchiya Toshio Kurihara Kentaro Ishii Shujiro Tsuji Nobuhito Ikeuchi Fuminori Moriyasu | 2010 | World Journal of Gastrointestinal Endoscopy2010，2，2： | 1 |
| 8 | Endoscopic ultrasonography-guided biliary drainage显示文摘 | Takao Itoi Atsushi Sofuni Fumihide Itokawa Takayoshi Tsuchiya Toshio Kurihara Kentaro Ishii Shujiro Tsuji Nobuhito Ikeuchi Junko Umeda Fuminori Moriyasu Akihiko Tsuchida | 2010 | Journal of Hepato - Biliary - Pancreatic Sciences2010，，5： | 1 |
| 9 | Novel single transluminal gateway transcystic multiple drainages after EUS-guided drainage for complicated multilocular walled-off necrosis (with videos)显示文摘 | Shuntaro Mukai Takao Itoi Atsushi Sofuni Fumihide Itokawa Toshio Kurihara Takayoshi Tsuchiya Kentaro Ishii Shujiro Tsuji Nobuhito Ikeuchi Reina Tanaka Junko Umeda Ryosuke Tonozuka Mitsuyoshi Honjo Fuminori Moriyasu | 2013 | Gastrointestinal Endoscopy2013，，： | 1 |
| 10 | Endoscopic removal and trimming of distal self-expandable metallic biliary stents显示文摘AIM:To evaluate the efficacy and safety of endoscopic removal and trimming of self-expandable metallic stents(SEMS).METHODS:All SEMS had been placed for distal biliary strictures.Twenty-seven endoscopic procedures were performed in 19 patients in whom SEMS(one uncovered and 18 covered) removal had been attempted,and 8 patients in whom stent trimming using argon plasma coagulation(APC) had been attempted at Tokyo Medical University Hospital.The APC settings were:voltage 60-80 W and gas flow at 1.5 L/min.RESULTS:The mean stent indwelling period for all patients in whom stent removal had been attempted was 113.7 ± 77.6 d(range,8-280 d).Of the 19 patients in whom removal of the SEMS had been attempted,the procedure was successful in 14(73.7%) without procedure-related adverse events.The indwelling period in the stent removable group was shorter than that in the unremovable group(94.9 ± 71.5 d vs 166.2 ± 76.2 d,P = 0.08).Stent trimming was successful for all patients with one minor adverse event consisting of self-limited hemorrhage.Trimming time ranged from 11 to 16 min.CONCLUSION:Although further investigations on larger numbers of cases are necessary to accumulate evidence,the present data suggested that stent removal and stent trimming is feasible and effective for stent-related complications. | Kentaro Ishii Takao Itoi Atsushi Sofuni Fumihide Itokawa Takayoshi Tsuchiya Toshio Kurihara Shujiro Tsuji Nobuhito Ikeuchi Junko Umeda Fuminori Moriyasu Akihiko Tsuchida | 2011 | World Journal of Gastroenterology2011，17，21： | 1 |
| 11 | Endoscopic ultrasonography-guided biliary drainage显示文摘 | Takao Itoi Atsushi Sofuni Fumihide Itokawa Takayoshi Tsuchiya Toshio Kurihara Kentaro Ishii Shujiro Tsuji Nobuhito Ikeuchi Junko Umeda Fuminori Moriyasu Akihiko Tsuchida | 2010 | Journal of Hepato - Biliary - Pancreatic Sciences2010，，5： | 1 |
| 12 | Endoscopic ultrasonography-guided biliary drainage显示文摘 | Takao Itoi Atsushi Sofuni Fumihide Itokawa Takayoshi Tsuchiya Toshio Kurihara Kentaro Ishii Shujiro Tsuji Nobuhito Ikeuchi Junko Umeda Fuminori Moriyasu Akihiko Tsuchida | 2010 | Journal of Hepato - Biliary - Pancreatic Sciences2010，，5： | 1 |
| 13 | A newly designed plastic stent for EUS-guided hepaticogastrostomy: a prospective preliminary feasibility study (with videos)显示文摘 | Junko Umeda Takao Itoi Takayoshi Tsuchiya Atsushi Sofuni Fumihide Itokawa Kentaro Ishii Shujiro Tsuji Nobuhito Ikeuchi Kentaro Kamada Reina Tanaka Ryosuke Tonozuka Mitsuyoshi Honjo Shuntaro Mukai Mitsuru Fujita Fuminori Moriyasu | 2015 | Gastrointestinal Endoscopy2015，，2： | 1 |
| 14 | Perfusion Computerized Tomography Can Predict Pancreatic Necrosis in Early Stages of Severe Acute Pancreatitis显示文摘 | Yoshihisa Tsuji Hiroshi Yamamoto Shujiro Yazumi Yuji Watanabe Kazuhiro Matsueda Hiroyuki Yamamoto Tsutomu Chiba | 2007 | Clinical Gastroenterology and Hepatology2007，，12： | 1 |
| 15 | Peroral cholangioscopic diagnosis of biliary-tract diseases by using narrow-band imaging (with videos) <ce:link locator='fx1'/>显示文摘 | Takao Itoi Atsushi Sofuni Fumihide Itokawa Takayoshi Tsuchiya Toshio Kurihara Kentaro Ishii Shujiro Tsuji Fuminori Moriyasu Takuji Gotoda | 2007 | Gastrointestinal Endoscopy2007，，4： | 1 |
| 16 | Transpapillary incision of refractory circumscript pancreatic duct stricture using wire-guided snare forceps显示文摘Endoscopic therapy of pancreatic duct(PD)strictures using balloon dilation and pancreatic duct stent(PS) placement has been reported to improve the severity of abdominal pain in selected patients with chronic pancreatitis(CP).However,some strictures are refractory and require frequent PS exchange to control symptoms.We describe two cases of successful endoscopic PD incision for difficult PD stricture using a wireguided snare.The snare is partially opened within the strictured pancreatic duct while applying current,thus incising the duct.Although both cases were successful without complications we do not advocate that this method be used routinely because of the potential for severe complications,e.g.bleeding,ductal perforation or pancreatic parenchymal damage.In order to prevent these complications,we developed a wire-guided technique under fluoroscopic control.We think this procedure may be useful in patients with short,straight PD strictures.Although further study is required,this approach may have potential for selected patients with refractory PD strictures due to CP. | Takao Itoi Atsushi Sofuni Fumihide Itokawa Toshio Kurihara Takayoshi Tsuchiya Kentaro Ishii Shujiro Tsuji Nobuhito Ikeuchi Fuminori Moriyasu | 2010 | World Journal of Gastroenterology2010，16，12： | 1 |
| 17 | Clinical evaluation of a novel lumen-apposing metal stent for endosonography-guided pancreatic pseudocyst and gallbladder drainage (with videos)显示文摘 | Takao Itoi Kenneth F. Binmoeller Janak Shah Atsushi Sofuni Fumihide Itokawa Toshio Kurihara Takayoshi Tsuchiya Kentaro Ishii Shujiro Tsuji Nobuhito Ikeuchi Fuminori Moriyasu | 2012 | Gastrointestinal Endoscopy2012，，4： | 1 |
| 18 | New large-diameter balloon-equipped sphincterotome for removal of large bile duct stones (with videos)显示文摘 | Takao Itoi Atsushi Sofuni Fumihide Itokawa Toshio Kurihara Takayoshi Tsuchiya Kentaro Ishii Shujiro Tsuji Nobuhito Ikeuchi Junko Umeda Fuminori Moriyasu | 2010 | Gastrointestinal Endoscopy2010，，4： | 1 |
| 19 | Large balloon dilatation following endoscopic sphincterotomy using a balloon enteroscope for the bile duct stone extractions in patients with Roux-en-Y anastomosis显示文摘 | Takao Itoi Kentaro Ishii Atsushi Sofuni Fumihide Itokawa Toshio Kurihara Takayoshi Tsuchiya Shujiro Tsuji Nobuhito Ikeuchi Junko Umeda Rena Tanaka Fuminori Moriyasu | 2010 | Digestive and Liver Disease2010，，3： | 1 |
| 20 | Endoscopic ultrasound-guided placement of plastic vs. biflanged metal stents for therapy of walled-off necrosis: a retrospective single-center series显示文摘 | Shuntaro Mukai Takao Itoi Todd Baron Atsushi Sofuni Fumihide Itokawa Toshio Kurihara Takayoshi Tsuchiya Kentaro Ishii Shujiro Tsuji Nobuhito Ikeuchi Reina Tanaka Junko Umeda Ryosuke Tonozuka Mitsuyoshi Honjo Takuji Gotoda Fuminori Moriyasu Ichiro Yasuda | 2014 | Endoscopy2014，，： | 1 |
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