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| 1 | Endoscopic retrograde cholangiopancreatography for bile duct stones in patients with a performance status score of 3 or 4显示文摘BACKGROUND As the aging population grows worldwide,the rates of endoscopic retrograde cholangiopancreatography(ERCP)for common bile duct stones(CBDS)in older patients with a poor performance status(PS)have been increasing.However,the data on the safety and efficacy of ERCP for CBDS in patients with a PS score of 3 or 4 are lacking,with only a few studies having investigated this issue among patients with poor PS.AIM To examine the safety and efficacy of ERCP for CBDS in patients with a PS score of 3 or 4.METHODS This study utilized a retrospective multi-centered design of three institutions in Japan for 8 years to identify a total of 1343 patients with CBDS having native papillae who underwent therapeutic ERCP.As a result,1113 patients with a PS 0-2 and 230 patients with a PS 3-4 were included.One-to-one propensity-score matching was performed to compare the safety and efficacy of ERCP for CBDS between patients with a PS 0-2 and those with a PS 3-4.RESULTS The overall ERCP-related complication rates in all patients and propensity score-matched patients with a PS 0-2 and 3-4 were 9.0%(100/1113)and 7.0%(16/230;P=0.37),and 4.6%(9/196)and 6.6%(13/196;P=0.51),respectively.In the propensity score-matched patients,complications were significantly more severe in the group with a PS 3-4 than in the group with a PS 0-2 group(P=0.042).Risk factors for complications were indications of ERCP and absence of antibiotics in the multivariate analysis.Therapeutic success rates,including complete CBDS removal and permanent biliary stent placement,in propensity score-matched patients with a PS 0-2 and 3-4 were 97.4%(191/196)and 97.4%(191/196),respectively(P=1.0).CONCLUSION ERCP for CBDS can be effectively performed in patients with a PS 3 or 4.Nevertheless,the indication for ERCP in such patients should be carefully considered with prophylactic antibiotics. | Hirokazu Saito Yoshihiro Kadono Takashi Shono Kentaro Kamikawa Atsushi Urata Jiro Nasu Haruo Imamura Ikuo Matsushita Tatsuyuki Kakuma Shuji Tada | 2022 | World Journal of Gastrointestinal Endoscopy2022，14，4： | 2 |
| 2 | Low temperature synthesis of single-phase Ti 3 AlC 2 through reactive sintering Ti/Al/C powders显示文摘 | Yong Zou ZhengMing Sun Hitoshi Hashimoto Shuji Tada | 2007 | Materials Science & Engineering A2007，，： | 1 |
| 3 | Synthesis reactions for Ti3AlC2 through pulse discharge sintering Ti/Al4C3/TiC powder mixture显示文摘 | ZHOU Yong SUN Zhenming TADA Shuji HASHIMOTO H | 2006 | Scripta Materialia2006，55，9： | 1 |
| 4 | Effect of Al addition on low-temperature synthesis of Ti 3 SiC 2 powder显示文摘 | Yong Zou ZhengMing Sun Shuji Tada Hitoshi Hashimoto | 2007 | Journal of Alloys and Compounds2007，，1： | 1 |
| 5 | Synthesis reactions for Ti3AlC2 through pulse discharge sintering Ti/AlC- /TiC powder mixture 显示文摘 | ZOU Yong SUN Zhengming TADA Shuji | 2006 | Scripta Materialia2006，55，7： | 1 |
| 6 | Remaining issues of recommended management in current guidelines for asymptomatic common bile duct stones显示文摘Current guidelines for treating asymptomatic common bile duct stones(CBDS)recommend stone removal,with endoscopic retrograde cholangiopan-creatography(ERCP)being the first treatment choice.When deciding on ERCP treatment for asymptomatic CBDS,the risk of ERCP-related complications and outcome of natural history of asymptomatic CBDS should be compared.The incidence rate of ERCP-related complications,particularly of post-ERCP pancreatitis for asymptomatic CBDS,was reportedly higher than that of symptomatic CBDS,increasing the risk of ERCP-related complications for asymptomatic CBDS compared with that previously reported for biliopancreatic diseases.Although studies have reported short-to middle-term outcomes of natural history of asymptomatic CBDS,its long-term natural history is not well known.Till date,there are no prospective studies that determined whether ERCP has a better outcome than no treatment in patients with asymptomatic CBDS or not.No randomized controlled trial has evaluated the risk of early and late ERCP-related complications vs the risk of biliary complications in the wait-and-see approach,suggesting that a change is needed in our perspective on endoscopic treatment for asymptomatic CBDS.Further studies examining long-term complication risks of ERCP and wait-and-see groups for asymptomatic CBDS are warranted to discuss whether routine endoscopic treatment for asymptomatic CBDS is justified or not. | Hirokazu Saito Yoshihiro Kadono Takashi Shono Kentaro Kamikawa Atsushi Urata Jiro Nasu Haruo Imamura Ikuo Matsushita Shuji Tada | 2021 | World Journal of Gastroenterology2021，27，18： | 1 |
| 7 | Effect of AI Addition on Low-Temperature Synthesis of Ti3SiC2 Powder 显示文摘 | Zou Yong Sun ZhengMi:ag Tada Shuji | 2008 | Journal of Alloys and Compounds2008，461，12： | 1 |
| 8 | Effect of Al addition on pressureless reactive sintering of Ti3 SiC2 显示文摘 | Zhengming Sun Yong Zou Shuji Tada | 2006 | Scripta Materialia2006，55，： | 1 |
| 9 | Synthesis of single-phase Ti3 SiC2 with the assistance of liquid phase formation显示文摘 | Yong Zou Zhengming Sun Shuji Tada | 2007 | J Alloys Comp2007，441，： | 1 |
| 10 | Effect of Al addition on pressureless reactive sintering of Ti3SiC2 显示文摘 | Sun Z M Zou Y Shuji Tada | 2006 | Scripta Materialia2006，55，11： | 1 |
| 11 | Effect of Al addition on low-temperature synthesis of Ti3 SiC2 powder 显示文摘 | Yong Zou ZhengMing Sun Shuji Tada | | Journal of Alloys and Compounds0，，： | 1 |
| 12 | Effect of liquid reaction on the synthesis of Ti3SiC2 powder 显示文摘 | Yong Zou ZhengMing Sun Shuji Tada | 2008 | Ceramics International2008，34，： | 1 |
| 13 | Effect of Al addition on pressureless reactive sintering of Ti3SiC2显示文摘 | SUN ZhengMing ZOU Yong TADA Shuji | 2006 | Scripta Materialia2006，55，： | 1 |
| 14 | Synthesis reactions for Ti3SiC2 through pulse discharge sintering TiH2/Si/TiC powder mixture显示文摘 | ZOU Yong SUN Zheng Ming TADA Shuji HASHIMOTO Hitoshi | 2008 | Materials Research Bulletin2008，43，： | 1 |
| 15 | Effect of liquid reaction on the synthesis of Ti3SiC2 powder显示文摘 | ZOU YONG SUN ZHENGMING TADA SHUJI | 2008 | Ceramics Intemational2008，34，1： | 1 |
| 16 | Synthesis reactions for Ti3AlC2 through pulse discharge sintering Ti/AlC/TiC powder mixture 显示文摘 | Yong Zou Zhengming Sun Shuji Tada and Hitoshi Hashimoto | 2006 | Scripta Materialia2006，55，： | 1 |
| 17 | Current approaches and questions yet to be resolved for the prophylaxis of post-endoscopic retrograde cholangiopancreatography pancreatitis显示文摘Prophylaxis is important for post-endoscopic retrograde cholangiopancreatography(ERCP)pancreatitis(PEP),which is the most common and serious complication of ERCP.Although the current guidelines include independent patient-and procedure-related risk factors for PEP and available PEP prophylactic measures,the synergistic effect of these risk factors on PEP should also be considered,given that patients often harbor multiple risk factors.Furthermore,a combination of prophylactic measures is often selected in clinical practice.However,established methods estimating the synergistic effect of independent risk factors on PEP incidence are lacking,and evidence on the impact of combining prophylactic measures on PEP should be discussed.Selection of appropriate candidate patients for ERCP is also important to reduce the incidence of PEP associated with unnecessary ERCP.ERCP indications in patients with asymptomatic common bile duct stones(CBDSs)and in those with suspected CBDSs with no imaging-based evidence of stones are controversial.Further studies are warranted to predict the synergistic effect of independent risk factors on PEP,determine the best prophylactic PEP measures,and identify appropriate candidates for ERCP in patients with asymptomatic CBDSs and those with suspected CBDSs. | Hirokazu Saito Atsushi Fujimoto Kana Oomoto Yoshitaka Kadowaki Shuji Tada | 2022 | World Journal of Gastrointestinal Endoscopy2022，14，11： | 0 |
| 18 | Risk prediction of common bile duct stone recurrence based on new common bile duct morphological subtypes显示文摘Stones in the common bile duct(CBD) are reported worldwide, and this condition is majorly managed through endoscopic retrograde cholangiopancreatography(ERCP). CBD stone recurrence is an important issue after endoscopic stone removal. Therefore, it is essential to identify its risk factors to determine the necessity of regular follow-up in patients who underwent endoscopic removal of CBD stones. The authors identified that the S and polyline morphological subtypes of CBD were associated with increased stone recurrence. New morphological subtypes of CBD presented by the authors can be important risk predictors of recurrence after endoscopic stone removal. Furthermore, the new morphological subtypes of CBD may predict the risk of residual CBD stones or technical difficulty in CBD stone removal. Further studies with a large sample size and longer follow-up durations are warranted to examine the usefulness of the newly identified morphological subtypes of CBD in predicting the outcomes of ERCP for CBD stone removal. | Hirokazu Saito Shuji Tada | 2022 | World Journal of Gastrointestinal Surgery2022，14，8： | 0 |
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