|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | A deep learning-enabled portable imaging flow cytometer for cost-effective, highthroughput, and label-free analysis of natural water samples显示文摘We report a deep learning-enabled field-portable and cost-effective imaging flow cytometer that automatically captures phase-contrast color images of the contents of a continuously flowing water sample at a throughput of 100 mL/h.The device is based on partially coherent lens-free holographic microscopy and acquires the diffraction patterns of flowing micro-objects inside a microfluidic channel.These holographic diffraction patterns are reconstructed in real time using a deep learning-based phase-recovery and image-reconstruction method to produce a color image of each micro-object without the use of external labeling.Motion blur is eliminated by simultaneously illuminating the sample with red,green,and blue light-emitting diodes that are pulsed.Operated by a laptop computer,this portable device measures 15.5 cm×15 cm×12.5 cm,weighs 1 kg,and compared to standard imaging flow cytometers,it provides extreme reductions of cost,size and weight while also providing a high volumetric throughput over a large object size range.We demonstrated the capabilities of this device by measuring ocean samples at the Los Angeles coastline and obtaining images of its micro-and nanoplankton composition.Furthermore,we measured the concentration of a potentially toxic alga(Pseudo-nitzschia)in six public beaches in Los Angeles and achieved good agreement with measurements conducted by the California Department of Public Health.The cost-effectiveness,compactness,and simplicity of this computational platform might lead to the creation of a network of imaging flow cytometers for largescale and continuous monitoring of the ocean microbiome,including its plankton composition. | Zoltán Gӧrӧcs Miu Tamamitsu Vittorio Bianco Patrick Wolf Shounak Roy Koyoshi Shindo Kyrollos Yanny Yichen Wu Hatice Ceylan Koydemir Yair Rivenson Aydogan Ozcan | 2018 | Light(Science & Applications)2018，7，1： | 14 |
| 2 | Purification of lactic acid dehydrogenase from crude bovine heart extract by pH-peak focusing counter-current chromatography显示文摘 | Shibusawa Y Misu N Shindo H | 2002 | J Chromatography B2002，776，： | 1 |
| 3 | Relationship be tween radial and central arterial pulse wave and evaluation of central aortic pressure using the radial arterial pulse wave显示文摘 | Takazawa K Kobayashi H Shindo N | 2007 | Hyper tens Res2007，30，： | 1 |
| 4 | Involvement of microsomal triglyceride transfer protein in nonalcoholic steatohepatitis in novel spontaneous mouse model 显示文摘 | Shindo N Fujisawa T Sugimoto K | 2010 | Hepatology2010，52，6： | 1 |
| 5 | A seasonal model to simulate influenza oscillation in Tokyo显示文摘 | Urashima M Shindo N Okabe N | 2003 | Japanese Journal of Infectious Diseases2003，56，2： | 1 |
| 6 | Seasonal models of herpangi-na and hand-foot-mouth disease to simulate annual fluctuations inurban warming in Tokyo显示文摘 | Urashima M Shindo N Okabe N | 2003 | Jpn J Infect Dis2003，56，2： | 1 |
| 7 | Osteogenic differentiation of the mesenchymal progenitor cells, Kusa is suppressed by Notch signaling显示文摘 | Shindo K Kawashima N Sakamoto K | 2003 | Exp Cell Res2003，，： | 1 |
| 8 | Relationship between radial and central arterial pulse wave and evaluation of central aortic pressure using the radial arterial pulse wave 显示文摘 | Takazawa K Kobayashi H Shindo N | 2007 | Hypertens Res2007，30，3： | 1 |
| 9 | Problems involved in endovascular embolization of intracranial aneurysms with three - dimensional guglielmi detachable coils 显示文摘 | SHINDO A SAKAI N SAKAI H | 2001 | N Shinkei Geka2001，29，： | 1 |
| 10 | Seasonal models of herpangi- na and hand-foot-mouth disease to simulate annual fluctuations in ur- ban warming in Tokyo显示文摘 | URASHIMA M SHINDO N OKABE N | 2003 | Jpn J Infect Dis2003，56，2： | 1 |
| 11 | Gluteal muscle necrosis following transcatheter angiographic embolisation for retroperitoneal haemorrhage associated with pelvic fracture显示文摘 | Takahira N Shindo M Tanaka K | 2001 | Injury2001，32，1： | 1 |
| 12 | Small molecules that inhibit Vif-induced degradation of APOBEC3G显示文摘 | Matsui M Shindo K Izumi T Io K Shinohara M Komano J Kobayashi M Kadowaki N Harris R S Takaori-Kondo A | 2014 | Virol J2014，11，： | 1 |
| 13 | Blood supply of the parathyroid gland from the superior thyroid artery显示文摘 | Nobori M Saiki S Tanaka N Harihara Y Shindo S Fujimoto Y | 1994 | Surgery1994，115，4： | 1 |
| 14 | Scattering ofantiplane shear waves in a fiberreinforced composite medium with interfacial layers显示文摘 | SHINDO Y NIWA N | 1996 | Acta Mechanica1996，117，14： | 1 |
| 15 | Seasonal models of herpangina and hand-food-mouth disease to simulate annual fluctuations in urban warming in Tokyo 显示文摘 | Urashima M Shindo N Okabe N | 2003 | Jpnlnfect Dis2003，56，2： | 1 |
| 16 | Seasonal models of herpangina and hand-foot-mouth disease to simulate annual fluctuations in urban warming in Tokyo显示文摘 | Urashima M Shindo N | 2003 | Japan Journal of Infectious Disease2003，56，： | 1 |
| 17 | Cefpiramide: antibacterial activity, pharmacokinetics, and clinical evaluation显示文摘 | Shindo K Oikawa N Chida S | 1990 | Jpn J Antibiot1990，43，1： | 1 |
| 18 | The development of effective heat and power use technology for residential in a PEFC co-generation system 显示文摘 | HIDEKI I SHINDO S KUNIHIRO N | 2002 | Journal of Power Sources2002，，106： | 1 |
| 19 | Angiogenic effects of adrenomedullin in ischemia and tumor growth 显示文摘 | Iimuro S Shindo T Moriyama N | 2004 | Circ Res2004，95，4： | 1 |
| 20 | Synthetic retinoid Am80 reduces scavenger receptor expression and atherosclerosis in mice by inhibiting IL-6 显示文摘 | Takeda N Manabe 1 Shindo T | 2006 | Arterioscler Thromb Vasc Biol2006，26，5： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员