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| 1 | Shh signaling guides spatial pathfinding of raphespinal tract axons by multidirectional repulsion显示文摘相对,很少对在发展在下降 serotonergic raphespinal 道(RST ) 位于空间 pathfinding 下面的分子的机制被知道针的绳索,为疼痛的最重要的神经小径之一,感觉并且马达功能。我们提供证据藏匿板的声音的刺猬(嘘) 是的那块腹的地板为在 anterior-to-posterior (A-P ) 和 medial-to-lateral (M-L ) 的减少的坡度的建立负责在腹的针的绳索的方向在 serotonergic RST 轴突设计期间。嘘小径的下游的部件,修正了 1 (Ptch1 ) 并且 Smoothened (Smo ) ,在 serotonergic 被表示尾的缝原子核并且在下降 serotonergic RST 轴突充实。serotonergic RST 轴突的可散开的嘘排斥被显示被 Shh-Ptch1 相互作用和 Smo 的 derepression 调停。用合作文化试金,我们证明 A-P 分级排斥由嘘发信号调停了尾地通过了 serotonergic 轴突腹的针的绳索, M-L 分级排斥由发信号的嘘调停了同时限制了 serotonergic 轴突到腹、腹侧面的索。serotonergic RST 轴突的突出的 pathfinding 错误在各种各样的嘘, Ptch1 和 Smo 异种被观察。我们断定嘘调停信号的 multidirectional 排斥被要求在 A-P 方向推下降 serotonergic RST 轴突,并且在 M-L 方向把这些轴突限制为腹、腹侧面的索。这是 serotonergic RST 轴突的嘘调停信号的 multidirectional 排斥维持的第一示范在发展的空间轴突 pathfinding 针的绳索。 | Lijuan Song Yuehui Liu Yang Yu Xin Duan Shening Qi Yaobo Liu | 2012 | Cell Research2012，22，4： | 4 |
| 2 | Hierarchical streamline bundles显示文摘 | Shene C K Wang C L Yu H F | 2012 | IEEE Transactions on Visualization and Computer Graphics2012，18，8： | 1 |
| 3 | Drying kinetics of Chrysanthe muscinerariae folium flowers and pyrethrin content decay during drying显示文摘 | Shene C Petit-Breuihl X Inostroza X | 1999 | Drying Technology1999，4，17： | 1 |
| 4 | Hierarchical StreamlineBundles 显示文摘 | Yu H Wang C Shene C K | 2012 | IEEE Transactions on Visualization andComputer Graphics (SI 077-2626)2012，18，8： | 1 |
| 5 | A Vocabulary Approachto Partial Streamline Matching and Exploratory FlowVisualization 显示文摘 | Tao J Wang C Shene C K | 2015 | IEEE Transactions on Visualization andComputer Graphics (S1077-2626)2015，22，5： | 1 |
| 6 | A DeformationFramework for Focus + context Flow Visualization 显示文摘 | Tao J Wang C Shene C K | 2014 | IEEE Transactions on Visualization and ComputerGraphics (S1077-2626)2014，20，1： | 1 |
| 7 | Zymomonas mobilis CP4 fed-batch fermentations of glucose-fructose mixtures to ethanol and sorbitol显示文摘 | Shene C Brava S | 2001 | Appl Microbiol Biotechnol2001，57，： | 1 |
| 8 | Neural networks for the prediction of the state of zymomonas mobilis CP4 batch fermentations 显示文摘 | SHENE C DIEZ C BRAVO S | 1999 | Computers and Chemical Engineering1999，23，8： | 1 |
| 9 | Experimental study of residence time in a direct rotary dryer显示文摘 | Alvarez P I Shene C | 1994 | Drying Technology1994，12，7： | 1 |
| 10 | Microbial oils and fatty acids:effect of carbon source on docosahexaenoic acid(C22∶6 N-3,DHA)production by Thraustochytrid strains显示文摘 | SHENE C LEYTON A ESPARZA Y | 2010 | Journal of Soil Science&Plant Nutrition2010，10，3： | 1 |
| 11 | Experimental study of residence time in a direct rotary dryer 显示文摘 | Alvarez P I Shene C | 1994 | Drying Technology1994，12，7： | 1 |
| 12 | Neural network for the prediction of the state of zymomonas CP4 batch fermentations显示文摘 | | | Computers &Chemical Engineering0，23，： | 1 |
| 13 | Deficiencyofrac1blocksNADPHox-idaseactivation,inhibitsendoplasmicreticulum stress,andre-ducesmyocardialremodelinginamousemodeloftype1diabetes显示文摘 | LiJ ZhuH ShenE etal | 2010 | Diabetes2010，59，8： | 1 |
| 14 | Production of the exopolysacchzrides by Streptococcus thermophilus: effect of growth conditions on fermentation kinetics and intrinsic viscosity显示文摘 | SHENE C CANQUIL N BRAVO S | 2008 | International Journal of Food Microbiology2008，124，： | 1 |
| 15 | Randomised placebo-controlled trim of use of topical recombinant bovine basic fibroblast growth factor for second-degree burns 显示文摘 | FUX SHENE CHENY | 1998 | The Lancet1998，352，12： | 1 |
| 16 | Novel biological functions of interleukin 4 formation of tube-like structures by vascular endothelial cells in vitro and angiogenesis in vive显示文摘 | Fukushi J T Morisaki T Shene A | 1998 | Biochem Biophys Res Commun1998，250，2： | 1 |
| 17 | Production of the exopolysacchzrides by Streptococcus thermophilus: effect of growth conditions on fermentation kinetics and intrinsic viscosity显示文摘 | SHENE C CANQUIL N BRAVO S | 2008 | International Journal of Food Microbiology2008，124，： | 1 |
| 18 | Neural networks for the prediction of the state of zymomonas mobilis CP4 batch fermentations 显示文摘 | SHENE C DIEZ C BRAVO S | 1999 | Computers and Chemical Engineering1999，23，8： | 1 |
| 19 | Neural networks for the prediction of the state of zymomonas mobilis CP4 batch fermentations 显示文摘 | Shene C Diez C Bravo S | 1999 | Computers and Chemical Engineering1999，23，8： | 1 |
| 20 | A deformation framework for focus plus context flow visualization显示文摘 | Tao J Wang C L Shene C K | 2014 | IEEE Transactions on Visualization and Computer Graphics2014，20，1： | 1 |
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