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96篇 您的检索式:作者名="Shangari"
    题名 作者 年代 出处 被引量
1Peptides derived from BH3 domains of Bcl-2 family members:a comparative analysis of inhibition of Bcl 22,Bcl-x(L) and Bax oligomerization,induction of cytochrome c release,and activation of cell death显示文摘Shangary S Johnson DE 2002Biochemistry2002,41,30:1
2Small-molecule inhibi- tors of the MDM2-p53 protein-protein interaction to reactivate p53 function:a novel approach for cancer therapy 显示文摘SHANGARY S WANG S 2009Annu Rev Pharmacol Toxicol2009,49,26:1
3Peptides derived from BH3 domains of Bcl-2 family members:a comparative analysis of inhibition of Bcl-2,Bcl-x(L)and Bax oligomerization,induetion of cytochrome c release,and activation of cell death显示文摘 Johnson DE 2002Biochemistry2002,41,30:1
4Temporal activation of p53 by a specific MDM2 inhibitor is selectively toxic to tumors and leads to complete tumor growth inhibition 显示文摘Shangary S Qin D McEachern D 2008Proc Natl Acad Sci U S A2008,105,10:1
5Potent and orally active small- molecule inhibitors of the MDM2-p53 interaction 显示文摘Yu S Qin D Shangary S 2009J Med Chem2009,52,24:1
6Peptides derived from BH3domains of Bc I-2 family members:a comparative analysis of inhibition of Bcl-2,Bcl-x(L)and Bax oligomerization,induction of cytochrome c release,and activation of cell death显示文摘Shangary S Johnson DE 2002Biochemistry2002,41,30:1
7Reactivation of p53 by a specific MDM2 antagonist (MI-43) leads to p21-mediated cell cycle arrest and selective cell death in colon cancer 显示文摘SHANGARY S DING K QIU S 2008Mol Cancer Ther2008,7,6:1
8Temporal activation of p53 by a specific MDM2 inhibitor is selectively toxic to tumors and leads to complete tumor growth inhibition 显示文摘SHANGARY S QIN D MCEACHERN D 2008Proc Natl Acad Sci USA2008,105,10:1
9Peptides derived from BH3 domains of B cl-2 familymembers:a comparative analysis of inhibition of Bcl 22, Bcl-x(L)and Bax oligomerization,induction of cytochrome crelease, and activetion of cell death显示文摘Shangary S Johnson DE 2002Biochemistry2002,41,30:1
10The cytotoxic mechanism of glyoxal in- volves oxidative stress显示文摘SHANGARI N BRIEN P J 2004Biochemical Pharmacology2004,68,7:1
11Targeting the MDM2-p53 interaction for cancer therapy显示文摘Shangary S Wang S 2008Clin Cancer Res2008,14,:1
12Gossypol acts directly on the mitochondria to overcome Bcl-2-and Bcl-X L mediated apoptosis resistance显示文摘Oliver C L Miranda M B Shangary S 2005Mol Cancer Ther2005,4,1:1
13Reactivation of p53 by aspecific MDM2 antagonist( MI-43 ) leads to p21-mediated cell cycle arrest and selective cell death in colon cancer显示文摘SHANGARY S DING K QIU S 2008Mol Cancer Ther2008,7,:1
14Targeting the MDM2-p53 interaction for cancertherapy显示文摘Shangary S Wang S 2008Clin Cancer Res2008,14,17:1
15Peptides derived from BH3 domains of Bcl-2 family members: a comparative analysis of inhibition of Bcl-2,Bcl-x(L) and Bax oligomerization, induction of cytochrome c release,and activation of cell death显示文摘Shangary S Johnson DE 2002Biochemistry2002,41,30:1
16Small-molecule inhibitots of the MDM2-p53 protein-protein interaction to reactivate p53 function:a novel approach for cancer therapy显示文摘SHANGARY S WANG S 2009Annu Rev Pharmacol Toxicol2009,49,1:1
17Temporal activation of p53 by a specific MDM2 inhibitor is selectively toxic to tumors and leads to complete tumor growth inhibition 显示文摘SHANGARY S QIN D MCEACHERN D 2008Proc Natl Acad Sci USA2008,105,:1
18Marginal dietary thiamin deficiency induces the formation of colonic aberrant crypt loci (ACF) in rats显示文摘Bruce WR Furrer R Shangari N 2003Cancer Letter2003,20,:1
19Hepatocyte susceptibility to glyoxal is dependent on cell thiamin content显示文摘Nandita Shangari Rhea Mehta Peter J. O’Brien 2006Chemico-Biological Interactions2006,,2:1
20(-)-Gossypol acts directly on the mitochondria to overcome Bcl-2- and Bcl-X(L)-mediated apoptosis resistance显示文摘Oliver CL Miranda MB Shangary S 2005Mol Cancer Ther2005,4,1:1
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