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| 1 | Comparative analysis of the effectiveness of abiraterone before and after docetaxel in patients with metastatic castration-resistant prostate cancer显示文摘AIM: To study the efficacy and safety of abiraterone in patients with and without prior chemotherapy.METHODS: The databases including Pub Med and abstracts presented at the American Society of Clinical Oncology meetings up to April 2014 were systematically searched. Eligible studies included randomized controlled trials(RCTs) in which abiraterone plus prednisone was compared to placebo plus prednisone in metastatic castration-resistant prostate cancer(CRPC) patients. The summary incidence, relative risk, hazard ratio and 95%CI were calculated using random or fixed-effects models. Heterogeneity test was performed to test between-study differences in efficacy and toxicity.RESULTS: A total of two phase III RCTs were included in our analysis, with metastatic CPRC patients before(n = 1088) and after chemotherapy(n = 1195). Prior chemotherapy did not significantly alter the effect of abiraterone on overall survival(P = 0.92) and prostatespecific antigen(PSA) progression-free survival(P = 0.13), but reduced its effect on radiographic-prog-ression-free survival(P = 0.04), objective response rate(P < 0.001), and PSA response rate(P < 0.001). Prior chemotherapy significantly increased the specific risk of fluid retention and edema(P < 0.001) and hypokalemia(P < 0.001), but decreased the risk of all-grade hypertension(P < 0.001) attributable to abiraterone. There was no significant difference of cardiac disorders associated with abiraterone between the two settings(P = 0.58). CONCLUSION: Prior chemotherapy may reduce the effectiveness of abiraterone in patients with metastatic CRPC. | Raji Shameem Muhammad Saad Hamid Kevin Y Xu Shenhong Wu | 2015 | World Journal of Clinical Oncology2015，6，4： | 3 |
| 2 | 综述:利用柔性交流输电系统(FACTS)装置增强电力传输能力(英文)显示文摘全世界对电能的需求显著增长,但电能生产和传输能力却未相应提升。这导致电能消费者受多种问题困扰(如:电压和频率不稳定及电能质量问题)。为解决上述问题,需提升电力传输网的可用功率传输能力。世界各地的研究者采用柔性交流传输系统(FACTS)装置来提升这一能力。本文全面总结了FACTS控制器如何用于提升电力系统网的可用传输能力(ATC)和功率传输能力(PTC);针对不同因素,讨论不同FACTS设备的分类;结合相关统计结果,讨论FACTS设备的普及性和应用情况。此外,本文还包含六种主要FACTS装置的操作原理及其在提升ATC和PTC方面的应用。最后针对不同的控制算法,评估FACTS装置在提升ATC和PTC方面的性能。 | Fadi M.ALBATSH Saad MEKHILEF Shameem AHMAD H.MOKHLIS M.A.HASSAN | 2015 | Frontiers of Information Technology & Electronic Engineering2015，16，8： | 2 |
| 3 | Recent Insights into Signaling Responses to Cope Drought Stress in Rice显示文摘Drought is one of the hot topics needing urgent attention in the current era of climate change.It massively disturbs the rice growth and productivity and is becoming a serious threat.The drought avoidance strategies in rice include stomatal closure,cellular adaptation and changes in root development.Moreover,the endogenous plant hormones(abscisic acid and jasmonic acid)and reactive oxygen species have paramount importance in drought tolerance in rice.The drought tolerance induces modification in biochemical,molecular and physiological properties of plants.At the molecular level,expression of several transcription-factors is modulated which further determine the activation of drought responsive gene families.Mitogen activated protein kinases and Ca signaling pathways initiate an array of signaling cascade for mediating the gene expression in rice.Approaches,conventional breeding methods combined with modern emerging techniques such as genetic engineering,to improve rice drought tolerance were discussed.This review provided recent insights into major regulatory factors against drought stress,signaling mechanisms and molecular engineering strategies(including conventional transgenic and recent genome editing approaches)to induce drought tolerance in rice. | Muhammad Mahran ASLAM Muhammad Abdul Rehman RASHID Mohammad Aquil SIDDIQUI Muhammad Tahir KHAN Fozia FARHAT Shafquat YASMEEN Imtiaz Ahmad KHAN Shameem RAJA Fatima RASOOL Mahboob Ali SIAL ZHAO Yan | 2022 | Rice science2022，29，2： | 2 |
| 4 | Thoracic amyloidomas: Two ease reports of an evasive diagnosis 显示文摘 | Rosie Cresner Shameem Mahmood Jane Chen | 2014 | Jour- nal of the Royal Society of Medicine Open2014，5，6： | 1 |
| 5 | Relation of oxidant- antioxidant imbalance with disease progression in patients with asthma显示文摘 | Ahmad A Shameem M Husain Q | 2012 | Ann Thorac Med2012，7，4： | 1 |
| 6 | Improvement in target detection performance of pulse coded Doppler radar based on multicarrier modulation with fast Fourier transform(FFT) 显示文摘 | Prasad N N S S R K Shameem V Desai U B | 2004 | IEE Proceedings-Radar Sonar Navig2004，151，1： | 1 |
| 7 | Comparison of properties of steel slag and crushed limestone aggregate concretes 显示文摘 | Maslehuddin M Alfarabi M Shameem M | 2003 | Construction and Building Materials2003，17，2： | 1 |
| 8 | Comparison of properties of steel slag and crushed limestone aggregate concrete 显示文摘 | MASLEHUDDIN M SHARIF A M SHAMEEM M | 2003 | Construction and Building Materials2003，，17： | 1 |
| 9 | Solvent and catalyst free three-component coupling of carbonyl compounds, amines and triethylphosphite; a new synthesis of α-aminophosphonates显示文摘 | Chandrasekhar S Narsihmulu Ch Shameem Sultana S | 2003 | Synlett2003，4，： | 1 |
| 10 | Incidence and Risk of High-grade Stomatitis with mTOR Inhibitors in Cancer Patients显示文摘 | Raji Shameem Mario Lacouture Shenhong Wu | 2015 | Cancer Investigation2015，，3： | 1 |
| 11 | Super-capacitor based energy storage system for improved load frequency control显示文摘 | Mairajuddin M Shameem A L Shiekh J 1 | 2009 | Electric Power Systems Research2009，，79： | 1 |
| 12 | Effect ofγ-irradiation on peptide-containing hydrophilic poly(d,l-lactide-co-glycolide)microspheres显示文摘 | Shameem M Lee H Burton K | | 0，，06： | 1 |
| 13 | Comparison of Properties of Steel Slag and Crashed Limestone Aggregate Concretes显示文摘 | Maslehuddin M Alfarabi M Sharif Shameem M | 2003 | Construction and Building Materials2003，，17： | 1 |
| 14 | Enhanced photolumines- cence of Li3Ba2Gd3 (MoO4)8:Eu:+ red phosphor synthe- sized by mechanochemically assisted direct solid state reaction method at room temperature显示文摘 | Peter A J Shameem Banu I B | 2015 | Journal of Ma- terials Science: Materials in Electronics2015，26，4： | 1 |
| 15 | Nano energetic composites of CuO nano rods, nanowires, and Al-nanoparticles显示文摘 | Rajesh Shende Senthil Subraananian Shameem Hasan | 2008 | Propellants Explosives Pyrotechnics2008，33，2： | 1 |
| 16 | Improvement in Target Detection Performance of Pulse Coded Doppler Radar Based on Multicarrier Modula- tion with Fast Fourier Transform(FFT) 显示文摘 | Prasad N N S S R K Shameem V Desai U B | 2004 | IEE Proc Radar Sonar Navigation2004，151，1： | 1 |
| 17 | Durability of proprietary cementitious materials for use in wastewater transport systems显示文摘 | SARICIMEN H SHAMEEM M BARRY M S | 2003 | Cement and Concrete Composites2003，25，567： | 1 |
| 18 | Comparison of properties of steel slag and crashed limestone aggregate concretes显示文摘 | MASLEHUDDIN M SHARIF A M SHAMEEM M | 2003 | Construction and Building Materials2003，17，2： | 1 |
| 19 | Poly (ethylene glycol)(PEG)as a reusable solvent medium for organic synthesis application in the hech reaction显示文摘 | Chandrasekhar S Narsihmulu Ch Shameem S S | 2002 | Org Lett2002，4，： | 1 |
| 20 | Bacterial meningitis: rapid diagnosis and microbial profile: a multi- centered study显示文摘 | Shameem S Vinod Kumar CS Neelagund YF | 2008 | J Commun Dis2008，40，2： | 1 |
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