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| 1 | Single-cell RNA-seq uncovers dynamic processes and critical regulators in mouse spermatogenesis显示文摘 | Yao Chen Yuxuan Zheng Yun Gao Zhen Lin Suming Yang Tongtong Wang Qiu Wang Nannan Xie Rong Hua Mingxi Liu Jiahao Sha Michael D. Griswold Jinsong Li Fuchou Tang Ming-Han Tong | 2018 | Cell Research2018，28，9： | 26 |
| 2 | Effect of nanopore size on poly(dT)_(30) translocation through silicon nitride membrane显示文摘The nanopore size effect on translocation of poly(dT)30through Si3N4 membrane is investigated.In this paper,we report that the speed of the poly(dT)30 transport through Si3N4 nanopores can be slowed down by half through increasing the nanopore diameter from 4.8 nm to 10.8 nm.The results are consistent with our simulation results.Besides,the current blockage induced by DNA passing through the nanopore is less obvious as pore diameter is larger,which is in good agreement with the theoretical prediction.The conclusion about DNA transport through nanopores is beneficial for the design of DNA sequencing devices. | SI Wei SHA JingJie LIU Lei QIU YingHua CHEN YunFei | 2013 | Science China(Technological Sciences)2013，56，10： | 9 |
| 3 | Laboratory testing and molecular analysis of the resistance of wild and cultivated soybeans to cotton bollworm, Helicoverpa armigera(Hübner)显示文摘Identifying a superior soybean variety with high defoliator resistance is important to avoid yield loss. Cotton bollworm(Helicoverpa armigera Hübner) is one of the major defoliators of soybean(Glycine max [L.] Merr.) worldwide. In this study, we evaluated the effect of H. armigera larvae on ED059, a wild soybean(Glycine soja Sieb. et Zucc.), and three cultivated soybean varieties: Tianlong 2, PI 535807, and PI 533604, in choice and no-choice assays. The percentage of ED059 leaflets consumed by H. armigera was lower than that of the three cultivated soybeans. Larvae that fed on ED059 exhibited low weight gain and high mortality rate.Waldbauer nutritional indices suggested that ED059 reduced the growth, consumption, and frass production of H. armigera larvae. Larvae that fed on ED059 showed lower efficiency of conversion of ingested and of digested food than those that fed on Tianlong 2 and PI 533604.However, they showed statistically similar consumption index and approximate digestibility compared with those fed on the three cultivated soybeans. Quantitative real-time PCR analysis revealed that 24 h after insect attack, ED059 had higher transcript levels of Kunitz trypsin inhibitor 3, Cysteine proteinase inhibitor 2, and Nerolidol synthase 1 but a lower transcript level of Pathogenesis-related protein 1 than Tianlong 2. The gene expression results were consistent with the presence of higher levels of jasmonic acid(JA) and transcript levels of the JA biosynthesis enzyme allene oxide cyclase 3 in ED059 than in Tianlong 2. Our findings indicate that ED059 is a superior soybean line with strong insect resistance that may be mediated via the JA pathway. | Xiaoyi Wang Haifeng Chen Aihua Sha Rong Zhou Zhihui Shang Xiaojuan Zhang Chanjuan Zhang Limiao Chen Qingnan Hao Zhonglu Yang Dezhen Qiu Shuilian Chen Xinan Zhou | 2015 | The Crop Journal2015，3，1： | 6 |
| 4 | Tunable Syngas Synthesis from Photocatalytic CO2 Reduction Under Visible-Light Irradiation by Interfacial Engineering显示文摘Visible-light-driven CO2 photoreduction to achieve renewable materials,such as syngas,hydrocarbons,and alcohols,is a key process that could relieve environmental problems and the energy crisis simultaneously.Reduction of syngas products with diff erent H2:CO proportions is highly expected to produce high value-added chemicals in the industry.However,the development of technologies employing long-wavelength irradiation to achieve CO2 photoreduction and simultaneous tuning of the resultant H2:CO proportion remains a challenging endeavor.In this work,we carried out interfacial engineering by designing a series of heterostructured layered double-hydroxide/MoS2 nanocomposites via electrostatic self-assembly.The syngas proportion(H 2:CO)obtained from CO2 photoreduction could be modulated from 1:1 to 9:1 by visible-light irradiation(λ>400 nm)under the control of the interface-rich heterostructures.This work provides a cost-eff ective strategy for solar-tofuel conversion in an artificial photosynthetic system and describes a novel route to produce syngas with targeted proportions. | Conghui Qiu Sha Bai Wenjing Cao Ling Tan Junyan Liu Yufei Zhao Yu-Fei Song | 2020 | Transactions of Tianjin University2020，26，5： | 6 |
| 5 | Male spike strobiles with Gnetum affinity from the Early Cretaceous in western Liaoning,Northeast China显示文摘A fossil with Gnetum affinity was found in the Jianshangou Member(Barremian Age) of the Yixian Formation(Lower Cretaceous Epoch) of the Jehol Group in western Liaoning,northeastern China.The single fossil specimen is represented by both elongate-cylindrical male spike strobiles which borne within a nodal bract of cauliflorous branch.The spike strobiles have apparent nodes,invisible internodes,and numerous verticillate involucral collars.The microsporangiate units within involucral collars are not seen.The male spike strobiles with verticillate involucral collars occur exclusively in Gnetum;hence,the fossil strobiles are attributed to a new taxon,Khitania columnispicata gen.& sp.nov.,being closely related to Gnetum.The general isotopic dating suggests an age of Barremian,ca.125-122 million years(Myr) ago for the Jianshangou Member.The palaeoecological and palaeoclimatic inference based on the compositions of flora and fauna,and lithological characters of the fossil locality suggests that the fossil plants grew in a subtropical mesophytic forest and under a warmer climate.The remains of male spike strobiles are the first record of gnetalean macrofossil.It documents the evolution of the distinct gnetoid morphology and indicates a wider range of distribution of Gnetaceae in the Early Cretaceous than present day. | Shuang-Xing GUO jin-Geng SHA Li-Zeng BIAN Yin-Long QIU | 2009 | Journal of Systematics and Evolution2009，47，2： | 5 |
| 6 | Hybrid C a rrie r S prea d Based on 4-Weighted T ra nsform Spectrum System Fractional Fourier显示文摘Spread Spectrum (SS) is a promising technique to resist interference in wireless communication system. In order to further improve this capability, this paper proposes a Hybrid Carrier (HC) SS system, combining 4-Weighted Fractional Fourier Transform (4-WFRFT) with SS technique. In this HC-SS system, due to the property of 4-WFRFT, the signal energy of proposed system is distributed on the time-frequency plane more evenly and symmetrically, compared with the existing Single-Carrier (SC) and Multi-Carrier (MC) spread spectrum systems. In the selective channel, the proposed method can split the interference to a more broad range in order to reduce the influence, resulting in the better system performance. In addition, proposed system can be seen as the convergence of the existing SS techniques, which is a main feature in future. | Qiu Xin Sha Xuejun Mei Lin | 2012 | China Communications2012，9，1： | 4 |
| 7 | Experimental investigation on active acoustic flutter control显示文摘Experimenial studies on active acoustic fiutter control are carried out successfully in wind-tunnel after the theoretical study The experdrients verify the theory presented in the reference[1] and give valuable experimeotal results which predict a prondsing future of applying new techology and new ideas to the area of vibration induced by flow. | YANG Jun(Institute of Acoustics, Academic Sinica Beijing 100080)(State Key Lab. of Modern Acoustics, Naniing Universitg Naning 210093)HAN Fei QIU Xiaojun and SHA Jiazheng(State Key Lab. of Modern Acoustics, Nanjing Universitg Naning 210093) | 1997 | Chinese Journal of Acoustics1997，16，1： | 3 |
| 8 | Narrowband time delay estimation based on correlation coefficient显示文摘The problems of time delay estimation of narrowband signals are presented.The disadvantages of the existing algorithms are analyzed,and a new narrowband time delay estimating algorithm based on correlation coefficient is proposed.The original time delay information is transfered into the delay between the autocorrelation and cross-correlation function,and the precise estimating result by wave-comparison is given.The algorithm proposed here is also compared with other algorithms and its advantages over other algorithms are proved.The theoretical analysis and simulation show the effectiveness of the proposed algorithm. | Gao Yang Qiu Tianshuang Sha Lan Zhao Yanbin | 2009 | Journal of Systems Engineering and Electronics2009，20，5： | 3 |
| 9 | A Delayed-interval Delivery of An in vitro-fertilized Twin Pregnancy with Premature Rupture of Membranes显示文摘This article presents a case of conservative managements of an in vitro-fertilized twin pregnancy with early loss of the first fetus. A 37-year-old woman in the 21st week of a twin pregnancy delivered her one of the fetuses with unfortunate outcome after the premature rupture of membranes. The umbilical cord of the first fetus was ligated at the cervical level and the second surviving fetus was left in utero. In order to save the surviving fetus, conservative managements including combination of steroids, tocolytics, antibiotics and cervical cerclage were performed. The second fetus was delivered vaginally in the 27th week of pregnancy, 4 h after premature rupture of membranes of the remaining amniotic sac, 41 d after the first fetus was born. The child and the mother have been followed up for 4 years and they are healthy. Conservative managements including steroids, tocolytics, antibiotics and cervical cerclage in a closely monitored environment would be given following the delivery of the first fetus. Delayed-interval pregnancy appears to be safe for the mother and the remaining fetuses. | Hui-ling QIU Jian-zhi REN Ping LI Ai-guo SHA | 2013 | Journal of Reproduction and Contraception2013，24，2： | 2 |
| 10 | Combination of ARTP mutagenesis and color-mediated highthroughput screening to enhance 1-naphthol yield from microbial oxidation of naphthalene in aqueous system显示文摘Strain QCG of the aerobic bacteria Bacillus cereus is capable of producing l-naphthol from naphtha-lene,this strain was first isolated and characterized in this study.Strain QCG was mutagenized to enhance l-naphthol production,using atmospheric and room temperature plasma(ARTP)technology.Then,a microbial clone screening system was used to accelerate the operation.Meanwhile,a novel color-mediated high-throughput screening using 4-aminoantipyrine was performed to screen mutants.The optimal mutant strain QCG4 produced 19.58土0.34 mg·L-1-naphthol from naphthalene that was 47.32%higher than that of the original strain(13.29+0.28 mg·L-1).In addition,the optimal conditions for l-naphthol production via whole-cell catalysis of strain QCG4 were determined to be an OD600 of40,150 mg.L I naphthalene,and 7.5%dimethyl formamide as a co-solvent at pH 7.5 and 26℃ for 3 h,resulting in 41.18士0.12 mg·L-l-naphthol,i.e.,the mutant strain produces a 2.1-fold higher yield compared to the original strain. | Chenggang Qiu Alei Zhang Sha Tao Kang Li Kequan Chen Pingkai Ouyang | 2020 | Frontiers of Chemical Science and Engineering2020，14，5： | 2 |
| 11 | Application of Probiotics in Pig Industry as a Substitute of Antibiotics显示文摘Antibiotics plays a positive role in the development of livestock breeding and feed industry,but has also disadvantages impossible to overcome,so it is an inevitable trend of prohibiting application of antibiotics in feed.This paper reviewed concept and action mechanism of the antibiotics substitute—probiotics,and its application in piglets,growing and fattening pigs and sows. | Sha Wenfeng Zhu Juan Gu Yongjian Dai Hui Qiu Liangwei | 2015 | Animal Husbandry and Feed Science2015，7，1： | 2 |
| 12 | Catalyzing Random Access at Physical Layer for Internet of Things:An Intelligence Enabled User Signature Code Acquisition Approach显示文摘Exploiting random access for the underlying connectivity provisioning has great potential to incorporate massive machine-type communication(MTC)devices in an Internet of Things(Io T)network.However,massive access attempts from versatile MTC devices may bring congestion to the IIo T network,thereby hindering service increasing of IIo T applications.In this paper,an intelligence enabled physical(PHY-)layer user signature code acquisition(USCA)algorithm is proposed to overcome the random access congestion problem with reduced signaling and control overhead.In the proposed scheme,the detector aims at approximating the optimal observation on both active user detection and user data reception by iteratively learning and predicting the convergence of the user signature codes that are in active.The crossentropy based low-complexity iterative updating rule is present to guarantee that the proposed USCA algorithm is computational feasible.A closed-form bit error rate(BER)performance analysis is carried out to show the efficiency of the proposed intelligence USCA algorithm.Simulation results confirm that the proposed USCA algorithm provides an inherent tradeoff between performance and complexity and allows the detector achieves an approximate optimal performance with a reasonable computational complexity. | Xiaojie Fang Xinyu Yin Xuejun Sha Jinghui Qiu Hongli Zhang | 2021 | China Communications2021，18，10： | 1 |
| 13 | Laboratory testing and molecular analysis of the resistance of wild and cultivated soybeans to cotton bollworm, Helicoverpa armigera (Hübner)显示文摘 | Xiaoyi Wang Haifeng Chen Aihua Sha Rong Zhou Zhihui Shang Xiaojuan Zhang Chanjuan Zhang Limiao Chen Qingnan Hao Zhonglu Yang Dezhen Qiu Shuilian Chen Xinan Zhou | 2014 | The Crop Journal2014，，： | 1 |
| 14 | Ursolic acid ameliorates azoxymethane/dextran sulfate sodium-caused colorectal cancer by inhibition of Wnt signaling cascade显示文摘OBJECTIVE To investigate the pharmacological effect of ursolic acid(UA)on colitis-associated colorectal cancer(CAC)and its underlying mechanism based on the Wnt signaling pathway.METHODS The CAC model in mice was established by azoxymethane(AOM)combined and dextran sulfate sodium salt(DSS),accompanied by treatment with various dosages of UA and concomitant appraisal of body weight,stool and physical state of the mice.After the sacrifice of the mice,the tumor and length of the colorectum were measured,followed by retrieval of the liver,spleen,thymus and tumor tissue for downstream assays.The levels of inflammatory factors interleukin-6(IL-6),IL^(-1)βand C-reactive protein(CRP)in the tumor and serum were examined by enzyme-linked immunosorbent assay(ELISA).The pathological changes of colorectal tissues were observed by HE staining.The levels in tumors of Wnt/β-catenin signaling pathway-related proteins Wnt4,GSK-3β,β-catenin,TCF4,LEF1,c-Myc,cyclin D1 and apoptosis-related protein Bcl-2 were assayed by immunohistochemistry(IHC).The mRNA expressions of Wnt4,GSK-3β,β-catenin,TCF4,LEF1,c-Myc,cyclin D1,Bcl-2,Bax,caspase-9 and caspase-3 in tumors were detected by real-time quantitative RT-PCR(RT-qPCR).The protein levels of Wnt4,GSK-3β,β-catenin,TCF4,LEF1,c-Myc,cyclin D1,phospho-β-catenin,phospho-GSK-3β,Bcl-2 and Bax in tumors were probed by analyzed by Western blotting(WB).Also,RNA-seq was employed to assess the gut microbiota in the mice.RESULTS UA significantly ameliorated the symptoms of AOM/DSS-induced mouse CAC,evidenced by improved physical state,body weight,survival rate,colorectal length,the mass of liver,thymus,spleen,and decreased CAC load and colorectal mass.UA attenuated the levels of IL-6,IL^(-1)βand CRP in the mouse serum and colorectal tumor in a dose-dependent manner.HE staining showed that UA lessened carcinogenesis in the colorectum,with lower infiltration of lymphocytes,versus the control.IHC indicated that UA mitigated the expression of Wnt4,β-catenin,TCF4,LEF1,c-Myc,cyclin D1,Bcl-2,and promoted the GSK-3βexpression,compared with the control.Furthermore,UA diminished the mRNA expressions of Wnt4,β-catenin,TCF4,LEF1,c-Myc,cyclin D1,Bcl-2,and heightened the mRNA levels of GSK-3β,caspase-3,capase-9 and Bax in CAC.The results of mRNA expressions were verified by WB analysis,which revealed that UA impeded the protein expression of Wnt4,β-catenin,c-Myc,cyclin D1,Bcl-2,TCF4,LEF1,and elevated the protein levels of GSK-3βand Bax,phospho-β-catenin in mouse CAC.In addition,UA substantially ameliorated the gut microbiota to store the metabolic function in the mice with CAC.CONCLUSION Ursolic acid may protect against CAC,potentially by downregulation of Wnt/β-catenin signaling pathway activity and restoration of gut microbiota. | ZHAO Hui SUN Qiang ZENG Sha CHEN Li LIU Mao-lun REN Shan YANG Han MING Tian-qi TAO Qiu LU Jin-jian XU Hai-bo | 2021 | 中国药理学与毒理学杂志2021，35，10： | 1 |
| 15 | Mechanisms of active control of noise transmission through a panel into a cavity using a point force actuator on the panel r显示文摘 | QIU X SHA J YANG J | 1995 | Journal of Sound and Vibration1995，182，： | 1 |
| 16 | Band-gap-tailored random laser显示文摘A band-gap-tailored random laser with a wide tunable range and low threshold through infrared radiation is demonstrated. When fluorescent dyes are doped into the liquid crystal and heavily doped chiral agent system,we demonstrate a wavelength tuning random laser instead of a side-band laser, which is caused by the combined effect of multi-scattering of liquid crystal(LC) and band-gap control. Through rotating the infrared absorbing material on the side of the LC cell, an adjustable range for random lasing of 80 nm by infrared light irradiation was observed. | HONGBO Lu JIAN XING CHENG WEI JIANGYING XIA JUNQING SHA YUNSHENG DING GUOBING ZHANG KANG XIE LONGZHEN QIU ZHIJIA Hu | 2018 | Photonics Research2018，6，5： | 1 |
| 17 | Effects of acoustic excitation on the active flutter control显示文摘 | YANG J SHA J QIU X | 1996 | Journal of Sound and Vibration1996，190，： | 1 |
| 18 | Aspirin to prevent gentamicin-induced hearing loss 显示文摘 | Sha SH Qiu JH Schach J | 2006 | N Engl J Med2006，354，17： | 1 |
| 19 | Mapping Domain- and Age-Specific Functional Brain Activity for Children’s Cognitive and Affective Development显示文摘The human brain undergoes rapid development during childhood,with significant improvement in a wide spectrum of cognitive and affective functions.Mapping domain-and age-specific brain activity patterns has important implications for characterizing the development of children’s cognitive and affective functions.The current mainstay of brain templates is primarily derived from structural magnetic resonance imaging(MRI),and thus is not ideal for mapping children’s cognitive and affective brain development.By integrating task-dependent functional MRI data from a large sample of 250 children(aged 7 to 12)across multiple domains and the latest easy-to-use and transparent preprocessing workflow,we here created a set of age-specific brain functional activity maps across four domains:attention,executive function,emotion,and risky decision-making.Moreover,we developed a toolbox named Developmental Brain Functional Activity maps across multiple domains that enables researchers to visualize and download domain-and age-specific brain activity maps for various needs.This toolbox and maps have been released on the Neuroimaging Informatics Tools and Resources Clearinghouse website(http://gffzza9adc041c78b4b3bhnpx0v0bf96xf6kku.ffgz.tsg.suse.edu.cn/projects/dbfa).Our study provides domain-and age-specific brain activity maps for future developmental neuroimaging studies in both healthy and clinical populations. | Lei Hao Lei Li Menglu Chen Jiahua Xu Min Jiang Yanpei Wang Linhua Jiang Xu Chen Jiang Qiu Shuping Tan Jia-Hong Gao Yong He Sha Tao Qi Dong Shaozheng Qin | 2021 | Neuroscience Bulletin2021，37，6： | 1 |
| 20 | Selective Adsorption and Electrocatalysis of Polysulfides through Hexatomic Nickel Clusters Embedded in N-Doped Graphene toward High-Performance Li-S Batteries显示文摘The shuttle effect hinders the practical application of lithium-sulfur(Li-S)batteries due to the poor affinity between a substrate and Li polysulfides(LiPSs)and the sluggish transition of soluble LiPSs to insoluble Li2S or elemental S.Here,we report that Ni hexatomic clusters embedded in a nitrogen-doped three-dimensional(3D)graphene framework(Ni-N/G)possess stronger interaction with soluble polysulfides than that with insoluble polysulfides.The synthetic electrocatalyst deployed in the sulfur cathode plays a multifunctional role:(i)selectively adsorbing the polysulfides dissolved in the electrolyte,(ii)expediting the sluggish liquid-solid phase transformations at the active sites as electrocatalysts,and(iii)accelerating the kinetics of the electrochemical reaction of multielectron sulfur,thereby inhibiting the dissolution of LiPSs.The constructed S@Ni-N/G cathode delivers an areal capacity of 9.43mAhcm^(-2) at 0.1 C at S loading of 6.8 mg cm^(-2),and it exhibits a gravimetric capacity of 1104mAhg^(-1) with a capacity fading rate of 0.045%per cycle over 50 cycles at 0.2 C at S loading of 2.0 mg cm^(-2).This work opens a rational approach to achieve the selective adsorption and expediting of polysulfide transition for the performance enhancement of Li-S batteries. | Jiapeng Ji Ying Sha Zeheng Li Xuehui Gao Teng Zhang Shiyu Zhou Tong Qiu Shaodong Zhou Liang Zhang Min Ling Yanglong Hou Chengdu Liang | 2020 | Research2020，，1： | 1 |
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