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| 1 | Effect of electrical stimulation on neural regeneration via the p38-RhoA and ERK1/2-Bcl-2 pathways in spinal cord-injured rats显示文摘Although electrical stimulation is therapeutically applied for neural regeneration in patients, it remains unclear how electrical stimulation exerts its effects at the molecular level on spinal cord injury(SCI). To identify the signaling pathway involved in electrical stimulation improving the function of injured spinal cord, 21 female Sprague-Dawley rats were randomly assigned to three groups: control(no surgical intervention, n = 6), SCI(SCI only, n = 5), and electrical simulation(ES; SCI induction followed by ES treatment, n = 10). A complete spinal cord transection was performed at the 10^(th) thoracic level. Electrical stimulation of the injured spinal cord region was applied for 4 hours per day for 7 days. On days 2 and 7 post SCI, the Touch-Test Sensory Evaluators and the Basso-Beattie-Bresnahan locomotor scale were used to evaluate rat sensory and motor function. Somatosensory-evoked potentials of the tibial nerve of a hind paw of the rat were measured to evaluate the electrophysiological function of injured spinal cord. Western blot analysis was performed to measure p38-RhoA and ERK1/2-Bcl-2 pathways related protein levels in the injured spinal cord. Rat sensory and motor functions were similar between SCI and ES groups. Compared with the SCI group, in the ES group, the latencies of the somatosensory-evoked potential of the tibial nerve of rats were significantly shortened, the amplitudes were significantly increased, RhoA protein level was significantly decreased, protein gene product 9.5 expression, ERK1/2, p38, and Bcl-2 protein levels in the spinal cord were significantly increased. These data suggest that ES can promote the recovery of electrophysiological function of the injured spinal cord through regulating p38-RhoA and ERK1/2-Bcl-2 pathway-related protein levels in the injured spinal cord. | Min Cheol Joo Chul Hwan Jang Jong Tae Park Seung Won Choi Seungil Ro Min Seob Kim Moon Young Lee | 2018 | Neural Regeneration Research2018，13，2： | 6 |
| 2 | The mitochondrial genome encodes abundant small noncoding RNAs显示文摘识别的小 noncoding RNA 都被原子染色体远因此编码。这里,我们主要报导鼠科、人的 mitochondrial 染色体编码几千小 noncoding RNA,它是源于 mitochondrial 基因(主人基因) 的感觉抄本,并且我们称为这些小 RNA mitochondrial 编码染色体的小 RNA (mitosRNAs ) 。影响的 DICER inactivation,但是完全没废除 mitosRNA 生产。MitosRNAs 看起来是当前未辩别出的 mitochondrial ribonucleases 的产品。提高的表示在 vitro 他们的主人基因铺平的 mitosRNAs 的 Overexpression,和 dysregulated mitosRNA 表示通常在 vivo 与异常 mitochondrial 基因表示被联系。我们的数据证明除了 37 已知的 mitochondrial 基因,哺乳动物的 mitochondrial 染色体也编码丰富的 mitosRNAs,它可以在房间在 mitochondrial 基因表示的控制起一个重要规章的作用。 | Seungil Ro Hsiu-Yen Ma Chanjae Park Nicole Ortogero Rui Song Grant W Hennig Huili Zheng Yung-Ming Lin2 Loredana Moro Jer-Tsong Hsieh wei Yant | 2013 | Cell Research2013，23，6： | 3 |
| 3 | Optimal number and locations of power quality monitors considering system topology显示文摘 | WON Dongjun MOON Seungil | 2008 | IEEE Trans on Power Delivery2008，23，1： | 1 |
| 4 | Analysis of the Spectrum of a Carte- sian Perfectly Matched Layer (PML) Approximation to Acoustic Scattering Problems 显示文摘 | Seungil Kim Joseph E Pasciak | 2010 | Journal of Mathematical Analysis and Ap- plications2010，361，2： | 1 |
| 5 | Prolonged clinical benefit from the maintenance hormone therapy in patients with metastatic breast cancer显示文摘 | Seungtaek Lim Soohyeon Lee Jungwoo Han Byeong-Woo Park SeungIl Kim Seho Park Joo-Hang Kim Hye Jin Choi Joohyuk Sohn | 2013 | The Breast2013，，6： | 1 |
| 6 | Temporal domain processing for a synthetic aperture array显示文摘 | Seungil Kim | 2002 | IEEE Journal of oceanic engineering2002，27，2： | 1 |
| 7 | Colocalization of Cannabinoid Receptor 1 with Somatostatin and Neuronal Nitric Oxide Synthase in Rat Brain Hypothalamus显示文摘 | Shenglong Zou Rishi K Somvanshi Seungil Paik Ujendra Kumar | 2015 | Journal of Molecular Neuroscience2015，，2： | 1 |
| 8 | Temporal domain processing for a synthetic aperture array显示文摘 | Seungil Kim Dae Hee Youn CHungyong Lee | 2002 | IEEE Journal of oceanic engineering2002，27，2： | 1 |
| 9 | Temporal Domain Processing for a Synthetic Aperture,Array 显示文摘 | Seungil K Dae H Y Chungyong L | 2002 | IEEE J Ocean Eng2002，27，2： | 1 |
| 10 | An Empirical Analy- sis of the Characteristics of Residential Loca- tion Choice in the Rapidly Changing Korean Housing Market显示文摘 | Yi Changhyo Lee Seungil | 2014 | Cities2014，39，1： | 1 |
| 11 | Efficient Register Mapping and Allocation in LaTTe,An OpenSource Java Just-in-time Compiler显示文摘 | Byung-Sun Y Junpyo E SeungIl L | 2007 | IEEE Transactions on Parallel and Distributed Systems2007，18，1： | 1 |
| 12 | Adenovirus-based short hairpin RNA vectors containing an EGFP marker and mouse U6,human H1,or human U6 promoter显示文摘 | Seungil Ro Sung Jin Hwang Kenton M | 2005 | BioTechniques2005，38，4： | 1 |
| 13 | A PCR-based method for detection and quantification of small RNAs显示文摘 | Seungil R Chanjae P Jin J L | 2006 | Biochem Biophys Res Comm2006，351，： | 1 |
| 14 | Temporal domain processing for a synthetic aperture array显示文摘 | Seungil Kim Dae Hee Youn and CHungyong Lee | 2002 | IEEE Journal of oceanic engineering2002，27，2： | 1 |
| 15 | Analysis of Shear and Firiction Behaviors in End Milling Process显示文摘As a new approach to analyze shear behaviors in the shear plane and chip-tool friction behaviors in the chip-toolcontact region during an end milling process, this paper introduces a method to transform an up-end milling processto an equivalent oblique cutting process. In this approach, varying undeformed chip thicknesses and cutting forcesin the up-end milling process are replaced with the equivalent of oblique cutting ones. Experimental investigationsfor Inconel 718 were performed to verify the presented model. | Seunghan YANG Seungil CHANG Youngmoon LEE Heesool KIM Taejo KO | 2003 | Journal of Materials Science & Technology2003，19，z1： | 1 |
| 16 | Pathophysiological mechanisms underlying gastrointestinal symptoms in patients with COVID-19显示文摘Gastrointestinal(GI)symptoms,such as diarrhea,abdominal pain,vomiting,and anorexia,are frequently observed in patients with coronavirus disease 2019(COVID-19).However,the pathophysiological mechanisms connecting these GI symptoms to severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)infections remain elusive.Previous studies indicate that the entry of SARS-CoV-2 into intestinal cells leads to downregulation of angiotensin converting enzyme 2(ACE2)receptors resulting in impaired barrier function.While intestinal ACE2 functions as a chaperone for the amino acid transporter B0AT1,the B0AT1/ACE2 complex within the intestinal epithelium acts as a regulator of gut microbiota composition and function.Alternations to the B0AT1/ACE2 complex lead to microbial dysbiosis through increased local and systemic immune responses.Previous studies have also suggested that altered serotonin metabolism may be the underlying cause of GI disorders involving diarrhea.The findings of elevated plasma serotonin levels and high fecal calprotectin in COVID-19 patients with diarrhea indicate that the viral infection evokes a systemic inflammatory response that specifically involves the GI.Interestingly,the elevated proinflammatory cytokines correlate with elevated serotonin and fecal calprotectin levels further supporting the evidence of GI inflammation,a hallmark of functional GI disorders.Moreover,the finding that rectal swabs of COVID-19 patients remain positive for SARS-CoV-2 even after the nasopharynx clears the virus,suggests that viral replication and shedding from the GI tract may be more robust than that of the respiratory tract,further indicating fecal-oral transmission as another important route of viral spread.This review summarized the evidence for pathophysiological mechanisms(impaired barrier function,gut inflammation,altered serotonin metabolism and gut microbiota dysbiosis)underlying the GI symptoms in patients with COVID-19. | Byungchang Jin Rajan Singh Se Eun Ha Hannah Zogg Paul J Park Seungil Ro | 2021 | World Journal of Gastroenterology2021，27，19： | 0 |
| 17 | Dof转录因子的全基因组分析揭示辣椒发育和响应生物胁迫的功能特征显示文摘Dofs(DNA-binding with one zinc finger proteins)是植物特有的转录因子家族。Dof蛋白参与许多生物过程,如植物激素的产生,种子发育和环境适应。Dof蛋白已经在多种植物中被鉴定,但在辣椒中尚未开展类似的研究。我们在辣椒中鉴定出了33个可能的Dof基因(CaDofs)。为了了解CaDof基因的特征,我们分析了其系统进化关系、蛋白质基序和进化历史。我们将含有25个基序且分布在8条染色体上的33个CaDof基因分成4个族。我们发现CaDof基因的扩张可追溯到最近的复制事件。茄科种系形成之前,片段复制在CaDof家族基因中占主导地位。通过RNA-seq分析获得了CaDof基因表达谱,发现在对包括两种TMV菌株,辣椒斑驳病毒和辣椒疫霉菌的生物胁迫响应过程中,Ca Dof家族基因表现出了时间和病原特异性变化,这表明CaDof基因的功能具有多样性。这些结果不仅为研究Dof基因在生物胁迫中的响应提供有价值的信息,同时也有助于更好地理解Dof基因在辣椒和其他物种中的多重功能。 | Won-Hee Kang Seungill Kim Hyun-Ah Lee Doil Choi Seon-In Yeom 胡震竺(译) 孔秋生(译) | 2018 | 辣椒杂志2018，，2： | 0 |
| 18 | Hyundai—Kia运动型多功能车用V6—3L柴油机的研发显示文摘为了满足高级运动型多功能车的要求,新开发了一款V6—3L柴油机。该发动机的有效功率提供了良好的行驶舒适性,并达到欧4排放标准。通过燃烧和排气后处理方案的优化,该发动机的基本设计方案可成为未来达到欧5排放标准的基础。同时,为了满足美国Tier 2 Bin 5排放标准的要求,正在开发采用尿素喷射的氮氧化物排气后处理系统。 | Yohan Chi | 2009 | 国外内燃机2009，，5： | 0 |
| 19 | Author Correction: The mitochondrial genome encodesabundant small noncoding RNAs显示文摘It has been brought to our attention that our paper1 published in Cell Research in 2013 contains duplicated panels in Fig.3A(HX1_30-51 and mmu-let-7d).By examining the lab records,we found that the gel image of H-X1_30-51 appeared to be used as a place holder for mmu-let-7d(the loading control)when the original figure was first assembled.Unfortunately,it was never replaced by the real mmu-let-7d gel image.We repeated the PCR assays and added the mmu-let-7d gel image to the corrected Fig.3A.This correction does not affect the major findings and conclusions of this work.We apologize for this oversight. | Seungil Ro Hsiu-Yen Ma Chanjae Park Nicole Ortogero Rui Song Grant W.Hennig Huili Zheng Yung-Ming Lin Loredana Moro Jer-Tsong Hsieh Wei Yan | 2021 | Cell Research2021，31，12： | 0 |
| 20 | Suppression of the Resonant Scattering in Imperfect Acoustic Cloaking with a Lossy Medium in R^3显示文摘 | LI Meng-Lei KIM Seungil | 2014 | Chinese Physics Letters2014，31，5： | 0 |
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