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| 1 | Right trisegmentectomy with thoracoabdominal approach after transarterial embolization for giant hepatic hemangioma显示文摘Hepatic hemangiomas need to be treated surgically in cases where they are accompanied with symptoms, have a risk of rupture, or are hardly distinguishable from malignancy. The present authors conducted embolization of the right hepatic artery one day before an operation for a huge hemangioma accompanied with symptoms and confirmed a decrease in its size. The authors performed a right trisegmentectomy through a J-shape incision, using a thoracoabdominal approach, and safely removed a giant hemangioma of 32.0 cm × 26.5 cm × 8.0 cm in size and 2300 g in weight. Even for inexperienced surgeons, a J-shape incision with a thoracoabdominal approach is considered a safe and useful method when right-side hepatectomy is required for a large mass in the right liver. | Hyung-Il Seo Hong Jae Jo Mun Sup Sim Suk Kim | 2009 | World Journal of Gastroenterology2009，15，27： | 22 |
| 2 | Comparative analysis of radiofrequency ablation and resection for resectable colorectal liver metastases显示文摘AIM:To evaluate the therapeutic efficacy of radiofrequency ablation(RFA)for resectable colorectal liver metastases(CRLM)compared with that of resection.METHODS:Between June 2004 and June 2009,we retrospectively analyzed 29 patients with resectable CRLMs;17 patients underwent RFA,and 12 underwent hepatic resection.All of the patients were informed about the treatment modalities and were allowed to choose either of them.RFA including an intraoperative approach was performed by a radiologist;otherwise,hepatic resection was performed by a surgeon.Comparative analysis of the two groups was performed,including comparisons of gender,age,and clinical outcomes,such as primary tumor stage and survival rates.RESULTS:The mean tumor size was significantly larger in the resection group(3.59 cm vs 2.02 cm,P<0.01),and the 5-year overall survival(OS)rate for all patients was 44.7%.There was no difference in the 5-year OS rates between the RFA and resection groups(37.8%vs66.7%).Univariate analysis indicated significantly lower5-year OS rates for patients with a tumor size>3cm.The 5-year disease-free survival(DFS)rates were17.6%and 22.2%in the RFA and resection groups,respectively(P=0.119).Univariate analysis revealed that in cases of male gender,age>65 years,T stage<Ⅳ,absence of lymphatic metastasis,and tumor size>3 cm,RFA resulted in significantly inferior 5-year DFS rates compared with surgical resection.CONCLUSION:Surgical resection revealed superior outcomes in the treatment of resectable CRLMs,particularly in cases with a hepatic tumor size>3 cm. | Sanghwa Ko Hongjae Jo Seongpil Yun Eunyoung Park Suk Kim Hyung-Il Seo | 2014 | World Journal of Gastroenterology2014，20，2： | 12 |
| 3 | Clinicopathologic and molecular features associated with patient age in gastric cancer显示文摘AIM: To compare characteristics and prognosis of gastric cancer based on age.METHODS: A retrospective study was conducted on clinical and molecular data from patients(n =1658) with confirmed cases of gastric cancer in Seoul National University Bundang Hospital(Seoul, South Korea) from 2003 to 2010 after exclusion of patients diagnosed with lymphoma, gastrointestinal stromal tumor, and metastatic cancer in the stomach. DNA was isolated from tumor and adjacent normal tissue,and a set of five markers was amplified by polymerase chain reaction to assess microsatellite instability(MSI). MSI was categorized as high, low, or stable if ≥ 2, 1, or 0 markers, respectively, had changed.Immunohistochemistry was performed on tissue sections to detect levels of expression of p53, human epidermal growth factor receptor(HER)-2, and epidermal growth factor receptor. Statistical analysis of clinical and molecular data was performed to assess prognosis based on the stratification of patients by age(≤ 45 and> 45 years).RESULTS: Among the 1658 gastric cancer patients, the number of patients with an age ≤ 45 years was 202(12.2%; 38.9 ± 0.4 years) and the number of patients> 45 years was 1456(87.8%; 64.1 ± 0.3 years).Analyses revealed that females were predominant inthe younger group(P < 0.001). Gastric cancers in the younger patients exhibited more aggressive features and were at a more advanced stage than those in older patients. Precancerous lesions, such as atrophic gastritis and intestinal metaplasia, were observed less frequently in the older than in the younger group(P < 0.001). Molecular characteristics, including overexpression of p53(P < 0.001), overexpression of HER-2(P = 0.006), and MSI(P = 0.006), were less frequent in gastric cancer of younger patients. Cancer related mortality was higher in younger patients(P= 0.048), but this difference was not significant after adjusting for the stage of cancer.CONCLUSION: Gastric cancer is distinguishable between younger and older patients based on both clinicopathologic and molecular features, but stage is the most important predictor of prognosis. | Ji Yeon Seo Eun Hyo Jin Hyun Jin Jo Hyuk Yoon Cheol Min Shin Young Soo Park Nayoung Kim Hyun Chae Jung Dong Ho Lee | 2015 | World Journal of Gastroenterology2015，21，22： | 7 |
| 4 | Complex formulations, simple techniques: Can 3D printing technology be the Midas touch in pharmaceutical industry?显示文摘3 D printing is a method of rapid prototyping and manufacturing in which materials are deposited onto one another in layers to produce a three-dimensional object. Although 3 D printing was developed in the 1980 s and the technology has found widespread industrial applications for production from automotive parts to machine tools,its application in pharmaceutical area is still limited. However,the potential of 3 D printing in the pharmaceutical industry is now being recognized. The ability of 3 D printing to produce medications to exact specifications tailored to the needs of individual patients has indicated the possibility of developing personalized medicines. The technology allows dosage forms to be precisely printed in various shapes,sizes and textures that are difficult to produce using traditional techniques. However,there are various challenges associated with the proper application of3 D printing in the pharmaceutical sector which should be overcome to exploit the scope of this technology. In this review,an overview is provided on the various 3 D printing technologies used in fabrication of complex dosage forms along with their feasibility and limitations. | Shrawani Lamichhane Santosh Bashyal Taekwang Keum Gyubin Noh Jo Eun Seo Rakesh Bastola Jaewoong Choi Dong Hwan Sohn Sangkil Lee | 2019 | Asian Journal of Pharmaceutical Sciences2019，14，5： | 5 |
| 5 | Effect of biologically active fraction of Nardostachys jatamansi on cerulein-induced acute pancreatitis显示文摘AIM:To determine if the fraction of Nardostachys jatamansi(NJ) has the potential to ameliorate the severity of acute pancreatitis(AP).METHODS:Mice were administered the biologically active fraction of NJ,i.e.,the 4th fraction(NJ4),intraperitoneally,and then injected with the stable cholecystokinin analogue cerulein hourly for 6 h.Six hours after the last cerulein injection,the pancreas,lung,and blood were harvested for morphological examination,measurement of cytokine expression,and examination of neutrophil infiltration.RESULTS:NJ4 administration attenuated the severity of AP and lung injury associated with AP.It also reduced cytokine production and neutrophil infiltration and resulted in the in vivo up-regulation of heme oxygenase-1(HO-1).Furthermore,NJ4 and its biologically active fraction,NJ4-2 inhibited the cerulein-induced death of acinar cells by inducing HO-1 in isolated pancreatic acinar cells.CONCLUSION:These results suggest that NJ4 may be a candidate fraction offering protection in AP and NJ4 might ameliorate the severity of pancreatitis by inducing HO-1 expression. | Gi-Sang Bae Min-Sun Kim Kyoung-Chel Park Bon Soon Koo Il-Joo Jo Sun Bok Choi Dong-Sung Lee Youn-Chul Kim Tae-Hyeon Kim Sang-Wan Seo Yong Kook Shin Ho-Joon Song Sung-Joo Park | 2012 | World Journal of Gastroenterology2012，18，25： | 4 |
| 6 | Growth-promoting activity of Hominis Placenta extract on regenerating sciatic nerve显示文摘瞄准:Hominis 胎盘(HP ) 的摘录作为一个代理人在东方药被使用了改进生理的功能。现在的学习被进行调查在一个试验性的臀部的神经损害动物模型的 HP 处理是否在在损害以后改革周围神经纤维上生产支持生长的效果。方法:在 HP 被注入一个臀部的神经损害地点以后,在蛋白质层次的变化被西方的弄污和染色分析的免疫荧光在再生神经区域分析。为对轴索新生的量的评价,一种后退的跟踪技术被用来识别相应于改革轴突的神经元细胞体,并且在有教养的背侧根的神经突长出的程度轧了感觉神经元从经历了一处臀部的神经挤压伤的动物准备了的神经胶质( DRG )在神经原收集前的 7 d 被分析。结果:在受伤臀部的神经的轴索的联系生长的蛋白质(GAP-43 ) 的正式就职层次被 HP 处理提高。HP 处理(Cdc2 ) 也,在调整两极分裂周期 2 上面,蛋白质在受伤臀部的神经的远侧的树桩铺平。导致的 Cdc2 蛋白质在 Schwann 房间被检测,建议那项 Cdc2 激酶活动可以涉及改革经由 Schwann 房间增长的轴突的支持生长的活动。由后退的跟踪的房间身体测量显示 HP 治疗在改革马达轴突产生了重要增加。最后,有教养的 DRG 感觉神经元的 HP 处理显著地增加了神经突树枝状和延伸。结论:HP 支持受伤臀部的轴突的新生由在调整象 GAP-43 和 Cdc2 那样的新生相关的蛋白质因素的合成上面。 | Tae-beom SEO In-sun HAN Jin-hwan YOON In-chan SEOL Yun-sik RIM Hyun-kyung JO Joung-jo AN Kwon-eui HONG Young-bae SEO Dong-hee KIM Seung-kiel PARK Deok-chun YANG Uk NAMGUNG | 2006 | Acta Pharmacologica Sinica2006，27，1： | 2 |
| 7 | Boarding issue in a commercial flight for patients with cavitary pulmonary tuberculosis: A case report显示文摘BACKGROUND Several studies have demonstrated that airborne transmission of Mycobacterium tuberculosis bacteria from patients with active pulmonary tuberculosis(TB) to other passengers or crew members can occur during long flights. As such, non-infectious TB patients are usually allowed to undertake air travel after taking the appropriate anti-TB drugs. However, the global guidelines for air travel for patients with TB are inconsistent and insufficiently detailed with respect to cavitary pulmonary TB(CPTB).CASE SUMMARY Here, we report a case in which a patient with multiple CPTB was permitted air travel, following negative sputum acid-fast bacilli smear tests after administration of proper anti-TB medication. The patient’s culture results were pending.CONCLUSION This case revealed that more specific guidelines regulating air travel for patients with CPTB are necessary. | Woori Jo Chuiyong Pak Yangjin Jegal Kwang Won Seo | 2020 | World Journal of Clinical Cases2020，8，3： | 2 |
| 8 | Highly reliable processes for embedding discrete passive components into organic substrates显示文摘 | Han Seo Cho Sukhyeon Cho Jihong Jo Haenam Seo Byongmoon Kim Jegwang Yoo | 2008 | Microelectronics Reliability2008，，5： | 1 |
| 9 | Diversity of Rotavirus Strain Circulated in Gwangju, Republic of Korea显示文摘 | Min Ji Kim Hye Sook Jeong Seon Gyeong Kim Se Mi Lee Sun Hee Kim Hye-Young Kee Eun-hye Jo Hye-jung Park Dong-Ryong Ha Eun Sun Kim Kye-Won Seo Jae Keun Chung | 2014 | Osong Public Health and Research Perspectives2014，，： | 1 |
| 10 | PPAR agonists treatment is effective in a nonalcoholic fatty liver disease animal model by modulating fat- ty-acid metabolic enzymes 显示文摘 | Seo YS Kim JH Jo NY | 2008 | J Gastroenterol Hepatol2008，23，1： | 1 |
| 11 | PPAR agonists treatment is effec- tive in a nonalcoholic fatty liver disease animal model by modulat- ing fatty-acid metabolic enzymes显示文摘 | Seo Y S Kim J H Jo N Y | 2008 | Journal of gastroenterology and hepatology2008，23，1： | 1 |
| 12 | CO 2 capture characteristics of dry sorbents in a fast fluidized reactor显示文摘 | Chang-Keun Yi S.H. Jo Y. Seo S.D. Park K.H. Moon J.S. Yoo J.B. Lee C.K. Ryu | 2006 | Studies in Surface Science and Catalysis2006，，： | 1 |
| 13 | A state observer for nonlinear systems and its application to ball and beam system显示文摘 | Jo N H Seo J H | 2000 | IEEE Trans on Automatic Control2000，45，5： | 1 |
| 14 | Sizeedependent magnetic properties of colloidal Mn3O4 and MnO nanoparticles 显示文摘 | Seo W S Jo H H Lee K | 2004 | Angezv Cherre Int Ed2004，43，9： | 1 |
| 15 | Indoor and outdoor bioaerosol levels at recreation facilities,elementary schools,and homes 显示文摘 | Wan-Kuen Jo Young-Jun Seo | 2005 | Chemo- sphere2005，61，11： | 1 |
| 16 | PPAR agonists treatment is effective in a nonalcoholic fatty liver disease animai model by modulating fatty-acid metabolic enzymes显示文摘 | Seo YS Kim JH Jo NY | 2008 | J Gastroenterol Hepatol2008，23，1： | 1 |
| 17 | The effect of rat bone marrowderived mesenchymal stem cells transplantation for restoration ofolfactory disorder显示文摘 | Jo H Jung M Seo DJ | 2015 | Bioehem Biophys Res Commun2015，467，2： | 1 |
| 18 | Decentralized H∞ -controller design 显示文摘 | Seo J H Jo H C Lee S | 1999 | Automatica1999，35，8： | 1 |
| 19 | Soft Tissue Balancing of Varus Arthritic Knee in Minimally Invasive Surgery Total Knee Arthroplasty:Comparison between Posterior Oblique Ligament Release and Superficial MCLRelease显示文摘 | Seo J G Moon Y W Jo B C | 2013 | Knee Surg Relat Res2013，25，2： | 1 |
| 20 | Modification and Minimiza- tion of Spinel (MgO · Al2 O3 ) Inclusions Formed in Ti Added Steel Melts 显示文摘 | Seo C W Kim S H Jo S K | 2010 | Metallurgical and Materials Transactions2010，41，4： | 1 |
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