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| 1 | Biosynthesis of silver nanoparticles by using mangrove plant extract and their potential mosquito larvicidal property显示文摘Objective:To identify the larvicidal activities of silver nano particles synthesised with Rhizophora mucronata(R.mucronata) leaf extract against the larvae of Aedes aegypti(Ae.aegypti) and Culex quinquefasciatus(Cx.quinquefasciatus).Methods:In vitro larvicidal activities such as LC50 and LC90 were assessed for the Ae.aegypti and Cx.quinquefasciatus larval species.Further, characterisation such as UV,XRD,FTIR and AFM analysis were carried out for the synthesised silver nano particles.Results:The LC50 value of the synthesised silver nano particle was identified as 0.585 and 0.891 mgg/L for Ae.aegypti and Cx.quinquefasciatus larvae respectively. Further,the LG90 values are also identified as 2.615 and 6.291 mg/L for Ae.aegypti and Cx. quinquefasciatus species respectively.The synthesised silver nanoparticles have maximum absorption at 420 nm with the average size of 60-95 nm.The XRD data showed 20 intense values with various degrees such as 37.10°,47.66°,63.97°and 70.01°.The FTIR data showed prominent peaks in(3 426.89,2 925.49,2 869.56,2 346.95,1 631.49,1 031.73,669.18 and 455.12) different ranges.Conclusions:The biosynthesis of silver nanoparticles with leaf aqueous extract of R. mucronata provides potential source for the larvicidal activity against mosquito borne diseases. | M Gnanadesigan M Anand S Ravikumar M Maruthupandy V Vijayakumar S Selvam M Dhineshkumar AK Kumaraguru | 2011 | Asian Pacific Journal of Tropical Medicine2011，4，10： | 4 |
| 2 | Characterization of cytotoxic compound from marine sediment derived actinomycete Streptomyces avidinii strain SU4显示文摘Objective:To investigate the cytotoxic activity of actinomycete isolated from marine sediment.Methods:In the present study the DNA was isolated and the ITS region of 16s rRNA was amplified by polymerase chain reaction,using two universal bacterial primers,1492K(5'-GGTTACCTTG'TTAC GACTT-3')and Eubac27F(5'-AGAGTTTGATCCTGGCTC AG-3').The amplified products were purified using TIANgel mini purification kit,ligated to MD18-T simple vector(TaKaRa),and transformed into competent cells of Escherichia coli DH5α.16S rRNA gene fragment was sequenced using forward primer M13F(-47)and reverse primer M13R(-48).Blast search sequence similarity was found against the existing non-redundanl nucleotide sequence database thus,identified as Streptomyces sp SU,Streptomyces rubralavandulae strain SU1,Streptomyces cacaoi strain SU2,Streptomyces cavourensis strain SU3,Streptomyces avidinii strain SU4,Streptomyces globisporus strain SU5,Streptomyces variabilis strain SU6,Streptomyces coelicolor strain SU 7.Among the eight identified isolates,one actinomycete Streptomyces avidinii strain SU4 was selected for further study.Results:Crude extract of the actinomycete isolate exhibited IC_(50)in 64.5μg against Hep-2 cell line,250μg in VERO cell line.This value is very close to the criteria of cytotoxicity activity for the crude extracts,as established by the American National Cancer Institute(NCI)is in IC_(50)<30μg/mL.The CC MS analysis showed that the active principle might be 1,2-benzenedicarboxylic acid,bis(2-methylpropyl)ester(12.17%),isooctyl phthalate(15.29%)with the retention time 15.642 and 21.612,respectively.Conclusions:This study clearly proves that the marine sediment derived actinomycetes with bioactive metabolites can be expected to provide high quality biological material for high throughout biochemical and anticancer screening programs.These results help us to conclude that the potential of using metabolic engineering and post genomic approaches to isolate more bioactive compounds and make their possible commercial application is not far off. | Sudha S Masilamani Selvam M | 2012 | Asian Pacific Journal of Tropical Biomedicine2012，2，10： | 2 |
| 3 | Surface characterisation of anodic films of Pb-Sn alloy electrodes:the effect of Sn on the photeelectrochemical properties显示文摘 | MUKHOPADHYAY I SELVAM P SHARON M | 1997 | Materials Chemistry and Physics1997，49，2： | 1 |
| 4 | H-MOR: Density functional investigation for the relative strength of Brnsted acid sites and dynamics simulation of NH3 protonation-deprotonation显示文摘 | ELANANY M VERCAUTEREN D P KOYAMA M KUBO M SELVAM P BROCLAWIK E MIYAMOTO A | 2006 | J Mol Catal A: Chem2006，243，1： | 1 |
| 5 | Design, synthesis, biological evaluation and molecular docking of curcumin analogues as antioxidant, cyclooxygenase inhibitory and anti- inflammatory agents 显示文摘 | Selvam C Sanjay M Jachaka R T | 2005 | Bioorg Med Chem Lett2005，15，： | 1 |
| 6 | The influence of inorganic oxidants and metal ions on semiconductor sensitized photodegradation of 4-fluorophenol显示文摘 | Selvam K Muruganandham M Muthuvel I | 2007 | Chem Eng J2007，128，1： | 1 |
| 7 | 查看详情显示文摘 | Rauscher M Selvam T Schwieger W Freude D | | 0，，： | 1 |
| 8 | Design,synthesis,biological evaluation and molecular docking of curcumin analogues as antioxidant,cyclooxygenase inhibitory and anti-inflammatory agents显示文摘 | Selvam C Jachak S M Thilagavathi R | 2005 | Bioorg Med Chem Lett2005，15，7： | 1 |
| 9 | Extended release nicotinic acid - a novel oral agent for phosphate control显示文摘 | Sampathkumar K Selvam M Sooraj Y S | 2006 | Int Urol Nephro12006，38，1： | 1 |
| 10 | The influence of inorganic oxidants and metal ions on semiconductor sensitized photodegradation of 4 - fluorophenol 显示文摘 | K Selvam M Muruganandham I Muthuvel | 2007 | Chemical Engineering Journal2007，128，1： | 1 |
| 11 | Electrochemical synthesis of self-organized TiO2 nanotubular structures using an ionic liquid BF4 显示文摘 | Paramasivam I M acak J M Selvam T | 2008 | Eleetroehim Acta2008，54，2： | 1 |
| 12 | Microwave-assisted preparation and sintering of mullite and mullite-zirconia composites from metal organics显示文摘 | Ravi B G Praveen V Selvam M P | 1998 | Materials Research Bulletin1998，33，10： | 1 |
| 13 | An investigation into occasional White Spot Syndrome Virus outbreak in traditional paddy cum prawn fields in India显示文摘 | Selvam D G Mujeeb Rahiman K M Mohamed Hatha A A | | 0，，： | 1 |
| 14 | Electrodeposition of zinc-manganese alloy from sulphate citrate bath显示文摘 | SELVAM M GURUVAIAH S | 1989 | Bulletin of Electrochemistry1989，5，5： | 1 |
| 15 | Serf assembly of silver( I ) complexes containing 1,4-Bis benzene 显示文摘 | Tzeng B C Banik M Selvam T S | 2013 | Cryst Growth Des2013，13，10： | 1 |
| 16 | Redox-active selenium compounds--from toxicity and cell death to cancer treatment 显示文摘 | Misra S Boylan M Selvam A | 2015 | Nutrients2015，7，5： | 1 |
| 17 | Computer modeling of flow around bridge using LES and FEM显示文摘 | Selvam R P Tarini M J Larsen A | 1998 | Journal of Wind Engineering and Industrial Aerodynamics1998，7778，： | 1 |
| 18 | Extended release nicotinic acid-a novel oral agent for phosphate control显示文摘 | Sampathkumar K Selvam M Sooraj Y S | 2006 | Int Urol Nephrol2006，38，： | 1 |
| 19 | Computer modelling offlow around bridges using LES and FEM显示文摘 | Selvam R P Tarini M J Larsen A | 1998 | Journal ofWind Engineering and Industrial Aerodynamics1998，7778，： | 1 |
| 20 | Design,synthesis,biological evaluation and molecular docking of curcumin analogues as antioxidant,cyclooxygenase inhibitory and anti-intlamttsatoty agents显示文摘 | SELVAM C JACHAK S M THILAGAVATHIR | 2005 | Bioorg Medic Chem Letters2005，15，3： | 1 |
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