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| 1 | Surgical management of moderate ischemic mitral valve regurgitation: Where do we stand?显示文摘Ischemic mitral regurgitation(IMR) represents a common complication after myocardial infarction. The valve is anatomically normal and the incompetence is the result of papillary muscles displacement and annular dilatation, causing leaflets tethering. Functionally the leaflets present a restricted systolic motion due to tethering forces that displaces the coaptation surface toward the left ventricle apex. The patients present poor left ventricular function at the time of surgery and the severity of the mitral regurgitation increases the risk of mortality. Currently there is general agreement to treat surgically severe IMR nevertheless strong evidences for patient with moderate insufficiency remains poor and proper treatment debated. The most effectivesurgical approach for the treatment of IMR remains debated. Some authors demonstrated that coronary artery bypass graft(CABG) alone is beneficial in patients with IMR. Conversely, in most patients, moderate IMR will persist or worsen after CABG alone which translate in higher long-term mortality as a function of residual mitral regurgitation severity. A probable reason for this unclear surgical management of functional MR is due to the contemporary suboptimal results of reparative techniques. The standard surgical treatment of chronic IMR is CABG associated with undersized annuloplasty using complete ring. Though, the recurrence of mitral regurgitation remains high(> 30%) because of continous left ventricle remodeling. To get better long term results, in the last decade, several subvalvular procedures in adjunct to mitral anuloplasty have been developed. Among them, surgical papillary muscle relocation represents the most appreciated option capable to restore normal left ventricle geometry. In the next future new preoperative predictors of increased mitral regurgitation recurrence are certainly needed to find an individual time period of treatment in each patient with moderate IMR. | Khalil Fattouch Sebastiano Castrovinci Giacomo Murana Marco Moscarelli Giuseppe Speziale | 2014 | World Journal of Cardiology2014，6，11： | 5 |
| 2 | Aortic valve stenosis: treatments options in elderly high-risk patients显示文摘 | Khalil Fattouch Sebastiano Castrovinci Patrizia Carita | 2016 | Journal of Geriatric Cardiology2016，13，6： | 4 |
| 3 | Aortic stenosis: insights on pathogenesis and clinical implications显示文摘大动脉的狭窄(作为) 是在西方的人口的普通的瓣膜的心疾病,与在在 75 年的成年人的 3% 的估计的全面流行。为了理解它的 patho 生物的过程,代表优先级。在老病人,作为通常包含 trileaflet 阀门并且被叫作退化石灰质的过程。科学证据建议活跃 “ 的参与; atherosclerosis-like”在开始阶段的致病退化作为。到矛盾,前进能被不同力量驾驶(例如在发炎和石灰化之间的机械应力,基因因素和相互作用) 。改进理解为阻止并且禁止疾病的发展和前进介绍潜在地新的治疗学的目标。而且,在临床的实践管理作为病人暗示概括动脉粥样硬化患者表明的评估(即,在里面冠并且颈动脉动脉) 甚至为预示的原因。在 counselling 老病人,风险层化应该超过通用风险分数探讨单个脆弱。在这些,问候,合作病态,和特别地那些连接了到全球动脉粥样硬化患者负担,应该小心地被调查以便为侵略治疗策略定义风险 / 利益比率。我们在场在致病的卓见的详细概述就象可能的实际含意。 | Patrizia Carita Giuseppe Coppola Giuseppina Novo Giuseppa Caccamo Marco Guglielmo FabioBalasus Salvatore Novo Sebastiano Castrovinci Marco Moscarelli Khalil Fattouch Egle Corrado | 2016 | Journal of Geriatric Cardiology2016，13，6： | 3 |
| 4 | Papillary muscle relocation in conjunction with valve annuloplasty improve repair results in severe ischemic mitral regurgitation显示文摘 | Khalil Fattouch Patrizio Lancellotti Sebastiano Castrovinci Giacomo Murana Roberta Sampognaro Egle Corrado Marco Caruso Giuseppe Speziale Salvatore Novo Giovanni Ruvolo | 2012 | The Journal of Thoracic and Cardiovascular Surgery2012，，6： | 1 |
| 5 | Mitral valve annuloplasty and papillary muscle relocation oriented by 3-dimensional transesophageal echocardiography for severe functional mitral regurgitation显示文摘 | Khalil Fattouch Giacomo Murana Sebastiano Castrovinci Claudia Mossuto Roberta Sampognaro Maria Giuliana Borruso Emanuela Clara Bertolino Giuseppa Caccamo Giovanni Ruvolo Patrizio Lancellotti | 2012 | The Journal of Thoracic and Cardiovascular Surgery2012，，4： | 1 |
| 6 | Minimally invasive aortic valve surgery显示文摘大动脉的阀门疾病是影响约 2% 一般成年人口的流行混乱。外科的大动脉的阀门代替是为征兆的病人的标准答案治疗。这治疗可论证地证明了安全、有效。在最后几十年,在一次尝试到减少外科的损伤,为大动脉的阀门代替的不同最低限度地侵略的途径被开发了并且现在逐渐地被利用。文学的记事评论被执行为最低限度地侵略的大动脉的阀门外科描述外科的技术并且从不同富有经验的中心报导结果。最低限度地侵略的大动脉的阀门代替与低 perioperative 病态,死亡和低变换率被联系到完整的 sternotomy。长期的幸存看起来至少比得上为常规完整的 sternotomy 报导了那。最低限度地侵略的大动脉的阀门外科,有部分上面的 sternotomy 的任何一个或恰好前面的 minithoracotomy 提供早术语、长期的好处。给这些好处,它可以为孤立的大动脉的阀门疾病被认为照顾的标准。 | Sebastiano Castrovinci Sam Emmanuel Marco Moscarelli Giacomo Murana Giuseppa Caccamo Emanuela Clara Bertolino Giuseppe Nasso Giuseppe Speziale Khalil Fattouch | 2016 | Journal of Geriatric Cardiology2016，13，6： | 0 |
| 7 | What are the benefits of a minimally invasive approach in frail octogenarian patients undergoing aortic valve replacement?显示文摘 | Yusuf S Abdullahi Leonidas V Athanasopoulos Marco Moscarelli Roberto P Casula Giuseppe Speziale Khalil Fattouch Sebastiano Castrovinci Thanos Athanasiou | 2016 | Journal of Geriatric Cardiology2016，13，6： | 0 |
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