5篇
您的检索式：作者名="Sebastiaan W"
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| 1 | Epithelioid sarcoma:still an only surgically curable disease显示文摘 | Sebastiaan A Robbert J Theo W | 2006 | Am Cancer Society2006，107，3： | 1 |
| 2 | Macrophages play a dual role during pulmonary tuberculosis in mice显示文摘 | Jaklien CL Theo T Sebastiaan W | 2005 | J Infect Diseases2005，191，1： | 1 |
| 3 | Macrophages play a dual role during pulmonary tuberculosis in mice 显示文摘 | Jaklien eL Theo T Sebastiaan W | 2005 | J Infect Diseases2005，191，： | 1 |
| 4 | Unspecified live kidney donation by urological patients显示文摘BACKGROUND Individuals with benign kidney disorders undergoing nephrectomy have three possibilities:Autotransplantation,with a certain risk of complications,but without a clear benefit;discarding the kidney;or living kidney donation.AIM To investigate whether patients with benign kidney disorders and a medical indication for nephrectomy are suitable as unspecified live kidney donors.METHODS We searched all clinical data from 1994-2019 for unspecified donors and their transplant recipients(n=160).Nine of these 160 donors had pre-existing kidney disorders necessitating nephrectomy and had decided to donate their kidney anonymously after discussing the possibility of kidney donation.We studied the clinical course of these nine donating patients and their transplant recipients.RESULTS Seven of nine donating patients indicated unbearable loin pain as the main complaint,one donating patient refused ureterocutaneostomy and one had two aneurysms of the renal artery.Postoperatively,seven donating patients described absence of pain and one a significant reduction after the nephrectomy.The average 1-year creatinine level in the donating patients was 88μmol/L and after a median of 6.9 years the average creatinine level was 86.6μmol/L.In the transplant recipients,one major complication occurred which led to death and in one transplant recipient graft function failed to normalize at first but has been stable for nine years now.Currently,all transplant recipients are off dialysis.CONCLUSION Our data show that patients undergoing nephrectomy as part of treatment in selected kidney disorders can function as live kidney donors. | Sebastiaan Ceuppens Hendrikus J A N Kimenai Karel W J Klop Willij C Zuidema Michiel G H Betjes Willem Weimar Jan N M IJzermans Frank J M F Dor Robert C Minnee | 2020 | World Journal of Transplantation2020，10，8： | 0 |
| 5 | Hemolysis results in impaired intestinal microcirculation and intestinal epithelial cell injury显示文摘AIM:To study the effect of circulating cell-free oxy-hemoglobin(FHb) on intestinal microcirculation and intestinal epithelial injury in a rat model. METHODS:To induce elevated intravascular circulating FHb,male Sprague-Dawley rats received water or FHb infusion.Microcirculatory changes in jejunum,ileum and colon were evaluated using fluorescent microspheres.Intestinal injury was quantified as plasmatic release of ileal lipid binding protein(iLBP) and verified by histological analysis of the ileum. RESULTS:Water and FHb infusions resulted,when compared with saline infusion,in reduced intestinal microcirculation(after 30 min P<0.05,or better;after 60 min FHb infusion P<0.05 for jejunum and colon) .Circulating FHb levels correlated significantly with release of iLBP(Spearman r=0.72,P=0.0011) .Epithelial cell injury of the villi was histologically observed after water and FHb infusions. CONCLUSION:This study shows that circulating FHb leads to a reduction in intestinal microcirculatory blood flow with marked injury to intestinal epithelial cells. These data support the hypothesis that circulating FHb contributes to the development of intestinal injury. | Sebastiaan J Hanssen Tim Lubbers Caroline M Hodin Frits W Prinzen Wim A Buurman Michael J Jacobs | 2011 | World Journal of Gastroenterology2011，17，2： | 0 |
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