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| 1 | 自发性脑出血管理指南 美国心脏协会/美国卒中协会针对医疗专业人员的指南显示文摘目的本指南旨在为自发性脑出血的诊断和治疗提供最新的全面推荐意见。方法利用PubMed进行规范化文献检索,检索时间至2013年8月底。撰写委员会成员通过远程电信会议讨论指南内容及推荐意见,采用美国心脏协会/美国卒中协会的疗效确定性水平和证据分级方案对推荐意见进行分级。由6位同行评议专家以及卒中委员会科学声明监督委员会和卒中委员会领导委员会成员对指南草案进行发表前审阅。结果本文为急性脑出血患者的医疗诊治提供了循证指南,重点包括诊断、凝血功能障碍和血压管理、继发性脑损伤防治、颅内压控制、外科治疗的作用、转归预测、康复、二级预防以及将来需要考虑的问题。本指南已纳入最新的3期临床试验结果。结论脑出血是一种需要进行早期积极救治的危重疾病。本指南为脑出血患者的目标导向治疗提供了一个框架。 | J. Claude Hemphill Ⅲ Steven M. Greenberg Craig S. Anderson Kyra Beckelr Bernard R. Bendok Mary Cushman Gordon L. Fung Joshua N. Goldstein R. LochMacdonald Pamela H Mitchell, Phillip A Scott,Magdy H Selim, Daniel Woo 高圆圆 徐欣 | 2015 | 国际脑血管病杂志2015,23,10: | 444 |
| 2 | Response of microbial communities to biochar-amended soils:a critical review显示文摘Application of biochar to soils changes soil physicochemical properties and stimulates the activities of soil microorganisms that influence soil quality and plant performance.Studying the response of soil microbial communities to biochar amendments is important for better understanding interactions of biochar with soil,as well as plants.However,the effect of biochar on soil microorganisms has received less attention than its influences on soil physicochemical properties.In this review,the following key questions are discussed:(i)how does biochar affect soil microbial activities,in particular soil carbon(C)mineralization,nutrient cycling,and enzyme activities?(ii)how do microorganisms respond to biochar amendment in contaminated soils?and(iii)what is the role of biochar as a growth promoter for soil microorganisms?Many studies have demonstrated that biochar-soil application enhances the soil microbial biomass with substantial changes in microbial community composition.Biochar amendment changes microbial habitats,directly or indirectly affects microbial metabolic activities,and modifies the soil microbial community in terms of their diversity and abundance.However,chemical properties of biochar,(especially pH and nutrient content),and physical properties such as pore size,pore volume,and specific surface area play significant roles in determining the efficacy of biochar on microbial performance as biochar provides suitable habitats for microorgan-isms.The mode of action of biochar leading to stimulation of microbial activities is complex and is influenced by the nature of biochar as well as soil conditions. | Kumuduni Niroshika Palansooriya James Tsz Fung Wong Yohey Hashimoto Longbin Huang Jörg Rinklebe Scott X.Chang Nanthi Bolan Hailong Wang Yong Sik Ok | 2019 | Biochar2019,1,1: | 34 |
| 3 | Intestinal microbiota in patients with nonalcoholic fatty liver disease显示文摘 | Marialena Mouzaki Elena M. Comelli Bianca M. Arendt Julia Bonengel Scott K. Fung Sandra E. Fischer Ian D. McGilvray Johane P. Allard | 2013 | Hepatology2013,,1: | 2 |
| 4 | Randomized Comparison of Tenofovir Disoproxil Fumarate vs Emtricitabine and Tenofovir Disoproxil Fumarate in Patients with Lamivudine-resistant Chronic Hepatitis B显示文摘 | Scott Fung Peter Kwan Milotka Fabri Andrzej Horban Mijomir Pelemis Hie-Won Hann Selim Gurel Florin A. Caruntu John F. Flaherty Benedetta Massetto Phillip Dinh Amoreena Corsa G. Mani Subramanian John G. McHutchison Petr Husa Edward Gane | 2013 | Gastroenterology2013,,: | 1 |
| 5 | Adefovir-resistant hepatitis B can be associated with viral rebound and hepatic decompensation显示文摘 | Scott K. Fung Pietro Andreone Steve H. Han K. Rajender Reddy Arie Regev Emmet B. Keeffe Munira Hussain Carmela Cursaro Pamela Richtmyer Jorge A. Marrero Anna S.F. Lok | 2005 | Journal of Hepatology2005,,6: | 1 |
| 6 | Impact of Viral Hepatitis on Outcomes after Liver Resection for Hepatocellular Carcinoma: Results from a North American Center显示文摘 | Jonghun J. Lee Peter T. W. Kim Sandra Fischer Scott Fung Steven Gallinger Ian McGilvray Carol-anne Moulton Alice C. Wei Paul D. Greig Sean P. Cleary | 2014 | Annals of Surgical Oncology2014,,8: | 1 |
| 7 | Agency Problems in Stock Market-driven Acquisitions显示文摘 | Scott Fung Hoje Jo Shih-Chuan Tsai | 2009 | Review of Accounting and Finance2009,8,4: | 1 |
| 8 | Adefovir-resistant hepatitis B can be associated with viral rebound and hepatic decompensation显示文摘 | Scott K. Fung Pietro Andreone Steve H. Han K. Rajender Reddy Arie Regev Emmet B. Keeffe Munira Hussain Carmela Cursaro Pamela Richtmyer Jorge A. Marrero Anna S.F. Lok | 2005 | Journal of Hepatology2005,,6: | 1 |
| 9 | Hemodynamic effects of inhaled nitric oxide in four patients with severe liver disease and pulmonary hypertension显示文摘 | AM De Wolf V Scott R Bjerke Y Kang D Kramer A Miro JJ Fung F Dodson T Gayowski IR Marino L Firestone | 1997 | Liver Transplantation1997,,6: | 1 |
| 10 | Nationwide retrospective study of hepatitis B virological response and liver stiffness improvement in 465 patients on nucleos(t)ide analogue显示文摘BACKGROUND Hepatitis B virus(HBV)nucleos(t)ide analog(NA)therapy reduces liver disease but requires prolonged therapy to achieve hepatitis B surface antigen(HBsAg)loss.There is limited North American real-world data using non-invasive tools for fibrosis assessment and few have compared 1st generation NA or lamivudine(LAM)to tenofovir disoproxil fumarate(TDF).AIM To assess impact of NA on virological response and fibrosis regression using liver stiffness measurement(LSM)(i.e.,FibroScan®).METHODS Retrospective,observational cohort study from the Canadian HBV Network.Data collected included demographics,NA,HBV DNA,alanine aminotransferase(ALT),and LSM.Patients were HBV monoinfected patients,treatment naïve,and received 1 NA with minimum 1 year follow-up.RESULTS In 465(median 49 years,37%female,35%hepatitis B e antigen+at baseline,84%Asian,6%White,and 9%Black).Percentage of 64(n=299)received TDF and 166 were LAM-treated with similar median duration of 3.9 and 3.7 years,respectively.The mean baseline LSM was 11.2 kPa(TDF)vs 8.3 kPa(LAM)(P=0.003).At 5-year follow-up,the mean LSM was 7.0 kPa in TDF vs 6.7 kPa in LAM(P=0.83).There was a significant difference in fibrosis regression between groups(i.e.,mean-4.2 kPa change in TDF and-1.6 kPa in LAM,P<0.05).The last available data on treatment showed that all had normal ALT,but more TDF patients were virologically suppressed(<10 IU/mL)(n=170/190,89%)vs LAM-treated(n=35/58,60%)(P<0.05).None cleared HBsAg.CONCLUSION In this real-world North American study,approximately 5 years of NA achieves liver fibrosis regression rarely leads to HBsAg loss. | Alnoor Ramji Karen Doucette Curtis Cooper Gerald Yosel Minuk Mang Ma Alexander Wong David Wong Edward Tam Brian Conway David Truong Philip Wong Lisa Barrett Hin Hin Ko Sarah Haylock-Jacobs Nishi Patel Gilaad G Kaplan Scott Fung Carla S Coffin | 2022 | World Journal of Gastroenterology2022,28,31: | 1 |
| 11 | Characterization of hepatitis B virus genotypes and quantitative hepatitis B surface antigen titres in North American tertiary referral liver centres显示文摘 | Stephen E. Congly Philip Wong Said A. Al‐Busafi Karen Doucette Scott K. Fung Peter Ghali Kevin Fonseca Robert P. Myers Carla Osiowy Carla S. Coffin | 2013 | Liver Int2013,,9: | 1 |
| 12 | Evaluation of APRI and FIB-4 scoring systems for non-invasive assessment of hepatic fibrosis in chronic hepatitis B patients显示文摘 | W. Ray Kim Thomas Berg Tarik Asselah Robert Flisiak Scott Fung Stuart C. Gordon Harry L.A. Janssen Pietro Lampertico Daryl Lau Jeffrey D. Bornstein Raul E. Aguilar Schall Phillip Dinh Leland J. Yee Eduardo B. Martins Seng Gee Lim Rohit Loomba J?rg Peterse | 2015 | Journal of Hepatology2015,,: | 1 |
| 13 | Guidelines for the Management of Spontaneous Intracerebral Hemorrhage: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association显示文摘 | J. Claude Hemphill Steven M. Greenberg Craig S. Anderson Kyra Becker Bernard R. Bendok Mary Cushman Gordon L. Fung Joshua N. Goldstein R. Loch Macdonald Pamela H. Mitchell Phillip A. Scott Magdy H. Selim Daniel Woo | 2015 | Stroke2015,,7: | 1 |
| 14 | Global capital market interdependence and spillover effect of credit risk: evidence from the 2007-2009 global financial crisis显示文摘 | William Cheung Scott Fung Shih-Chuan Tsai | 2010 | Applied Financial Economics (-)2010,,1: | 1 |
| 15 | SJES14121200095405显示文摘 | Amoreena C. Corsa Yang Liu John F. Flaherty Ben Mitchell Scott K. Fung Edward Gane Michael D. Miller Kathryn M. Kitrinos | 2014 | Clinical Gastroenterology and Hepatology2014,,12: | 1 |