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    题名 作者 年代 出处 被引量
1Discharge CMCeMa anci Oomplications After AmbulaLory Surgery显示文摘Scot I Macshall FgCA Frances C 1999Anesth Analg1999,88,:1
2Pharmacology and antitussive efficacy of 4- ( 3-trif- luoromethyl-pyridin-2 -yl ) -piperazine-1 -carboxylic acid ( 5-trifluoromethyl-pyridin-2-yl )-amide ( JNJ17203212 ), a transient receptor potential va- nilloid 1 antagonist in guinea pigs 显示文摘BHATTACHARYA A SCOT'I' B P NASSER N 2007J Pharmacol Exp Ther2007,323,2:1
3A further investigation of the lead - lag relationship be- tween the cash market and stock index futures market with the use of bid/ask quotes: the case of france显示文摘SHYY G VIJAYRAGHAVAN SCOT'I? - QUINN B 1996Journal of Futures Markets1996,,16:1
4Factors Affecting the Success of a Construction Project显示文摘CHAN P C SCOT'I' D CHAN P 2004Journal of Construc-tion Engineering and Management2004,130,1:1
5Stress-strain behavior of concrete confined by overlapping hoops at low and high-strain rates 显示文摘SCOT'I' B D PARK P PRIESTLEY M J N 1982J Am Concr Inst1982,79,1:1
6Geody- namics of the Central South Atlantic Conjugate Margins: Implications for Hydrocarbon Potential显示文摘Michael R L Scot I F Sumner H S 2010Petroleum Geoscience2010,16,:1
7Biologic protease inhibitors as novel therapeutic agents 显示文摘SCOT'I' C J TAGGART C C 2010Biochimie2010,92,11:1
8Fungal dysbiosis predicts the diagnosis of pediatric Crohn's disease显示文摘AIM To investigate the accuracy of fungal dysbiosis inmucosa and stool for predicting the diagnosis of Crohn's disease(CD). METHODS Children were prospectively enrolled in two medical centers: one university hospital and one private gastroenterology clinic in the city of Riyadh, Kingdom of Saudi Arabia. The children with confirmed diagnosis of CD by standard guidelines were considered cases, and the others were considered non-inflammatory bowel disease controls. Mucosal and stool samples were sequenced utilizing Illumina MiSeq chemistry following the manufacturer's protocols, and abundance and diversity of fungal taxa in mucosa and stool were analyzed. Sparse logistic regression was used to predict the diagnosis of CD. The accuracy of the classifier was tested by computing the receiver operating characteristic curves with 5-fold stratified cross-validation under 100 permutations of the training data partition and the mean area under the curve(AUC) was calculated. RESULTS All the children were Saudi nationals. There were 15 children with CD and 20 controls. The mean age was 13.9(range: 6.7-17.8) years for CD children and 13.9(3.25-18.6) years for controls, and 10/15(67%) of the CD and 13/20(65%) of the control subjects were boys. CD locations at diagnosis were ileal(L1) in 4 and colonic(L3) in 11 children, while CD behavior was non-stricturing and non-penetrating(B1) in 12 and stricturing(B2) in 3 children. The mean AUC for the fungal dysbiosis classifier was significantly higher in stools(AUC = 0.85 ± 0.057) than in mucosa(AUC = 0.71 ± 0.067)(P < 0.001). Most fungal species were significantly more depleted in stools than mucosal samples, except for Saccharomyces cerevisiae and S. bayanus, which were significantly more abundant. Diversity was significantly more reduced in stools than in mucosa. CONCLUSION We found high AUC of fungal dysbiosis in fecal samples of children with CD, suggesting high accuracy in predicting diagnosis of CD.Mohammad I El Mouzan Kirill S Korolev Mohammad A Al Mofarreh Rajita Menon Harland S Winter Ahmad A Al Sarkhy Scot E Dowd Ahmad M Al Barrag Asaad A Assiri 2018World Journal of Gastroenterology2018,24,39:1
9Surgical treatment of primary duo denal carcinoma: a personal series 显示文摘SCOT'I'-COOMBES DM WILLIAMSON RC 1994Br J Surg1994,81,10:1
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