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| 1 | Long-term durable response to lenalidomide in a patient with hepatic epithelioid hemangioendothelioma显示文摘Epithelioid hemangioendothelioma(EH)is a rare tumor arising from the vascular endothelial cells of soft tissue or visceral organs.The most common visceral site is the liver,where it is often involved in a multifocal man-ner known as hepatic EH(HEH).Surgical resection with curative intent represents the gold standard therapy.When surgery is not feasible,or in cases of metastatic disease,no standard medical treatment is currently indicated.In small series,drugs with anti-angiogenic activity(such as bevacizumab,sorafenib,thalidomide,and lenalidomide)have been proposed with promising results.We describe a 73-year-old man with multifocal non-resectable HEH treated with lenalidomide.Disease status was evaluated by abdominal ultrasound and magnetic resonance every four months.The patient was treated for a total of 39 mo with prolonged disease stabilization and,at the time of writing,is still under treatment with a good tolerance profile.During a short period of treatment discontinuation,the disease showed slight progression that immediately resolved after the reintroduction of lenalidomide.Lenalidomide may represent a valid treatment option for HEH due to its anti-angiogenic and antineoplastic activities.This preliminary result merits further study in a large series. | Maria Caterina Pallotti Margherita Nannini Claudio Agostinelli Simona Leoni Valerio Di Scioscio Anna Mandrioli Cristian Lolli Maristella Saponara Stefano Pileri Luigi Bolondi Guido Biasco Maria Abbondanza Pantaleo | 2014 | World Journal of Gastroenterology2014，20，22： | 9 |
| 2 | Benign metastasizing leiomyoma of the lung: PET findings显示文摘 | Scioscio V Feraco P Miglio L | 2009 | J Thorac Imaging2009，24，1： | 1 |
| 3 | Evaluation of the resistive index (RI) for the diagnosis of acute renal rejection in renal allografts from the same donor显示文摘 | Sciascia N Di Scioscio V Zompatori M | 2002 | Radiol Med(Torino)2002，103，3： | 1 |
| 4 | Benign metastasizing leio- myoma of the lung: PET findings 显示文摘 | di Scioscio V Feraco P Miglio L | 2009 | 3 Thorac Imaging2009，24，1： | 1 |
| 5 | Evaluation of the resistive index (RI) for the diagnosis of acute renal rejection in renal allografts from the same donor 显示文摘 | Sciascia N Di Scioscio V Zompatori M | 2002 | Radiol Med (Torino)2002，103，： | 1 |
| 6 | Benign metastasi- zing leiomyoma of the lung: PET findings 显示文摘 | di Scioscio V Feraeo P Miglio L | 2009 | J Thorac Imaging2009，24，1： | 1 |
| 7 | Pulmonary lymphangioleiomyornatosis in a karyotypically normal man without tuberous sclerosis complex 显示文摘 | Schiavina M Di Scioscio V Contini P | 2007 | Am J Respir Crit Care Med2007，176，： | 1 |
| 8 | Benign metastasizing leiomyoma of the lung:PET findings显示文摘 | Di Scioscio V Feraco P Miglio L | | 0，，01： | 1 |
| 9 | Benign metastasizing leiomyoma of the lung: PET findings显示文摘 | Di Scioscio V Feraco P Miglio L | 2009 | J Thorac Imaging2009，24，1： | 1 |
| 10 | Benign metastasizing leiomyoma of the lung:PET findings显示文摘 | di Scioscio V Feraco P Miglio L | | 0，，： | 1 |
| 11 | Laparoscopic Treatment of Gastric Gist : Report of 21 Cases and Literature’s Review显示文摘 | Fausto Catena Monica Battista Pietro Fusaroli Luca Ansaloni Valerio Scioscio Donatella Santini Maria Pantaleo Guido Biasco Giancarlo Caletti Antonio Pinna | 2008 | Journal of Gastrointestinal Surgery2008，，3： | 1 |
| 12 | Pulmonary lym- phangioleiomyomatosis in a karyotypically normal man with- out tuberous sclerosis complex 显示文摘 | Schiavina M Di Scioscio V Contini P | 2007 | Am J Respir Crit Care Med2007，176，1： | 1 |
| 13 | Pulmonary lymphangioleiomyomatosis in a karyotypically normal manwithout tuberous sclerosis complex显示文摘 | Schiavina M Di Scioscio V Contini P | 2007 | Am J Respir Crit Care Med2007，176，1： | 1 |
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