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| 1 | Long-term irritable bowel syndrome symptom control with reintroduction of selected FODMAPs显示文摘AIM To investigate the long-term effect of dietary education on a low fermentable oligosaccharide, disaccharide and polyol(FODMAP) diet on irritable bowel syndrome(IBS) symptoms and quality of life(Qo L).METHODS Participants with IBS(Rome III) were randomized to two groups. Group I commenced a low FODMAP diet at baseline. At three months, group II, so far a comparator group, crossed over to a low FODMAP diet while group I started re-challenging foods. All patients completed the IBS SSS(IBS symptom severity scoring system, 0-500 points increasing with severity), IBS Qo L questionnaire(0-100 increasing with Qo L), a FODMAP specific food frequency questionnaire and provided a stool sample at baseline, three and six months for microbiome analysis.RESULTS Fifty participants were enrolled into group I(n = 23) or group II(n = 27). Participants in both groups were similar in baseline values but with more men in group I. There was a significantly lower IBS SSS(275.6 ± 63.6 to 128.8 ± 82.5 vs 246.8 ± 71.1 to 203.6 ± 70.1)(P < 0.0002) and increased Qo L(68.5 ± 18.0 to 83 ± 13.4 vs 72.9 ± 12.8 to 73.3 ± 14.4)(P < 0.0001) in group I vs group II at 3 mo. The reduced IBS SSS was sustained at 6 mo in group I(160 ± 102) and replicated in group II(124 ± 76). Fiber intake decreased on the low FODMAP diet(33 ± 17 g/d to 21 ± 8 g/d)(P < 0.01) and after re-introducing FODMAP containing foods increased again to 27 ± 9 g/d. There was no change seen in the intestinal microbiome when participants adopted a low FODMAP diet.CONCLUSION This study demonstrated that a reduction in FODMAPs improves symptoms in IBS and this improvement can be maintained while reintroducing FODMAPs. | Ruth M Harvie Alexandra W Chisholm Jordan E Bisanz Jeremy P Burton Peter Herbison Kim Schultz Michael Schultz | 2017 | World Journal of Gastroenterology2017，23，25： | 5 |
| 2 | Neural mecha-nisms of observational learning显示文摘 | Burke C J Tobler P N Baddeley M Schultz W | 2010 | Proc Natl Acad Sci USA2010，107，14： | 1 |
| 3 | The effect of biofilms on turbulentboundary layers显示文摘 | Schultz M P Swain G W | 1999 | Journal of Fluids engineering1999，121，1： | 1 |
| 4 | The influence of biofilms on skin friction drag显示文摘 | Schultz M P Swain G W | 2000 | Biofouling2000，15，13： | 1 |
| 5 | Characterization of two divergent lineages of macaque rhadinoviruses related to Kaposi's sarcoma-associated herpesvirus 显示文摘 | Schultz E R Rankin G W Blanc M P | 2000 | Virol2000，74，： | 1 |
| 6 | The structure of environmental concern:Concern for self,other people,and the biosphere显示文摘 | Schultz P W | 2001 | Journal of Environmental Psychology2001，21，4： | 1 |
| 7 | Market structure and the intraday pattern of bid-ask spreads for NASDAQ securities显示文摘 | Chan K C Christie W G Schultz P H | 1995 | Journal of Business1995，68，1： | 1 |
| 8 | Why do Nasdaq Market Makers Avoid Odd--Eighth Quotes? 显示文摘 | Christie W Schultz P | 1994 | Journal of Finance1994，，49： | 1 |
| 9 | Changing behavior with normative feedback interventions: A field experiment on curbside recycling显示文摘 | Schultz P W | 1999 | Basic and Applied Social Psychology1999，21，： | 1 |
| 10 | Littering in context:Personal and environmental predictors of littering behavior显示文摘 | Schultz P W Bator R Tabanico J Bruni C Large L B | 2013 | Environment and Behavior2013，45，： | 1 |
| 11 | Perspective taking,environmental concern,and the moderating role of dispositional empathy显示文摘 | Sevillano V Aragones J I Schultz P W | 2007 | Environment and Behavior2007，39，5： | 1 |
| 12 | Improving the accuracy and precision of disease assessments : selection of methods and use of computer-aided training programs 显示文摘 | Nutter F W Schultz P M | 1995 | Canadian Journal of Plant Pathology1995，17，2： | 1 |
| 13 | The effect of sodium,potassium and ammonium ions on the conformation of the dimeric quadruplex formed by the Oxytricha nova telomere repeat oligonucleotide d(G4T4G4)显示文摘 | Schultze P Hud N V Smith F W | | 0，，15： | 1 |
| 14 | Responses of monkey dopamine neurons to reward and conditionel stimuli during suocessive steps of learning a delayed response task显示文摘 | Apicella P Ljungberg T | 1993 | J Neurosci1993，13，3： | 1 |
| 15 | Effects of alteplase beyond 3 h after stroke in the Echoplanar Imaging Thrombolytic Evaluation Trial (EPITHET): a placebo-controlled randomised trial显示文摘 | Stephen M Davis Geoffrey A Donnan Mark W Parsons Christopher Levi Kenneth S Butcher Andre Peeters P Alan Barber Christopher Bladin Deidre A De Silva Graham Byrnes Jonathan B Chalk John N Fink Thomas E Kimber David Schultz Peter J Hand Judith Frayne Graeme | 2008 | Lancet Neurology2008，，4： | 1 |
| 16 | Values as predictors of environmental attitudes:Evidence for consistency across 14 eountries 显示文摘 | Schultz P W Zelezny L (1999) | 1999 | Journal of Environmental Psychology1999，19，3： | 1 |
| 17 | Nomenclature of avian interferon proteins 显示文摘 | Lowenthal J W Staehelip P Schultz U | 2001 | J Interferon Cytokine Res2001，21，： | 1 |
| 18 | A novel QSAR approach for estimating toxicity of phenols 显示文摘 | Schultz T W Bearden A P Jaworska J S | 1995 | SAR and QSAR in Environmental Research1995，5，： | 1 |
| 19 | Implicit connections with nature 显示文摘 | Schultz P W Shriver C Tabanico J J Khazian A M ( 2004 ) | 2004 | Journal of Environmental Psychology2004，24，1： | 1 |
| 20 | Values and Their Relationship to Environmental Concern and Conservation Behavior 显示文摘 | Schultz P W Gonveia V V Cameron L D | 2005 | Journal of Cross-cuhural Psychology2005，36，4： | 1 |
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