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373篇 您的检索式:作者名="Schally"
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1Targeted therapy in advanced metastatic colorectal cancer: Current concepts and perspectives显示文摘The introduction of new cytotoxic substances as well as agents that target vascular endothelial growth factor(VEGF)and epidermal growth factor receptor(EGFR)signaling has improved clinical outcome of patients withmetastatic colorectal cancer(mCRC).In this review we summarize the most relevant clinical data on VEGF and EGFR targeting regimens in mCRC.The effects of available treatment strategies for mCRC are often temporary,with resistance and disease progression developing in most patients.Thus,new treatment strategies are urgently needed.Some GI peptides including gastrin and gastrin releasing peptide,certain growth factors such as insulin-like growth factor-ⅠandⅡand neuropeptides such as growth hormone releasing hormone(GHRH)are implicated in the growth of CRC.Experimental investigations in CRC with antagonistic analogs of bombesin/gastrin-releasing peptide,GHRH,and with cytotoxic peptides that can be targeted to peptide receptors on tumors,are summarized in the second part of the review.Florian Hohla Thomas Winder Richard Greil Ferenc G Rick Norman L Block rew V Schally 2014World Journal of Gastroenterology2014,20,20:3
2Mechanisms of antineplastic action of somatostatin analogs显示文摘Pollak MN Schally AV 1998Proc Soc Exp Biol Med1998,217,2:2
3Inhibitory effects of antagonists of bombesin/gastrin releasing peptide ( GRP ) and somatostatin analog ( RC160) on growth of HT-29 human colon cancers in nude mice显示文摘Radulovic S Schally AV 1994Acta oncologicd1994,33,6:2
4Inhibitory effect of bombesin gastrin releasing peptide antagonist RC-3095 and high dose of somatostatin analogue RC-160 on nitrosamine-induced pancreatic cancers in hamsters 显示文摘Szepeshazi K Schally AV Cai RZ 1991Cancer Res1991,51,3:2
5Antagonists of growth hormone-releasing hormone and somatostatin analog RC-160 inhibit the growth of the OV-1063 human epithelial ovarian cancer cell line xenografted into nude mice显示文摘 Schally AV Varga JL 2001J Clin Endocrinol Metab2001,86,5:1
6Effective treatment of experimental DU-145 prostate cancers with targeted cytotoxic somatostatin analog AN-238 显示文摘Plonowski A Schally A V Nagy A 2002Int J Oncol2002,20,2:1
7Human renal cell carcinoma expresses distinct binding sites for growth hormone-releasing hor- mone显示文摘Halmos G Schally AV Varga JL 2000Proc Natl Acad Sci U S A2000,97,10:1
8Inhibition of the UCI-107 human ovarian carcinoma cell line by a targeted cytotoxic analog of somatostatin,AN-238显示文摘 Schally AV Koppan M 2001Cancer2001,92,5:1
9Expression ofneuropeptide hormone receptors in human adrenal tumors and celllines: antiproliferative effects of peptide analogues显示文摘Ziegler CG Brown IW Schally AV 2009PNAS2009,106,15:1
10Inhibition of Growth of Experimental Human Endometrial Cancer by an Antagonist of Growth Hormone-Releasing Hormone显示文摘Engel Jorg B Keller Gunhild Schally Andrew V 2005Joumal of Clinical Endocrinology&Metabolism2005,90,6:1
11Human ovarian cancersexpress somatostatin receptors显示文摘Halmos G Sun B Schally AV 2000J Clin Endocrinol Metab2000,85,10:1
12Prac Soc Exp Biol Med显示文摘 Schally AV 1998217(2):143-1521998,217,2:1
13The LHRH antagonist cetrorelix:a review显示文摘Reissmann T Schally AV Bouchard P 2000Hum Reprod Update2000,6,4:1
14Somatostatin receptor subtype 2 sensitizes human pancreatic cancer cells to death ligand-induced apoptosis显示文摘Schally AV Guillermet J Saint-Laurent N 2003Proc Natl Acad Sci U S A2003,100,1:1
15Student learning by research显示文摘Schallies M Lembens A 2002J Biol Edu2002,37,:1
16Antagonist of growth hormone-releasing hormone induces apoptosis in LNCaP human prostate cancer cells through a Ca2+-dependent pathway显示文摘Rekasi Z Czompoly T Schally AV 2005Proc Natl Acad Sci U S A2005,102,9:1
17New Approaches to the Therapy of Various Tumors Based on Peptide Analogues显示文摘A. Schally 2008Horm Metab Res2008,,:1
18Effective inhibition of experimental human ovarian cancers with a targeted cytotoxic bombesin analogue AN-215 显示文摘Engle JB Keller G Schally AV 2005Clin Cancer Res2005,11,6:1
19The combination of antagonists of LHRH with antagonists of GHRH improves inhibition of androgen sensitive MDA-PCa-2b and LuCaP-35 prostate cancers显示文摘 Schally AV Zarandi M 2007Prostate2007,67,12:1
20Inhibition of theUCI-107 human ovarian carcinoma cell line by a targetedcytotoxic analog of somatostatin,AN-238显示文摘Plonowski A Schally AV Koppan M 2001Cancer2001,92,5:1
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