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| 1 | An architectural role for a nuclear noncoding RNA: NEAT1 RNA is essential for the structure of paraspeckles显示文摘 | Clemson CM Hutchinson JN Sara SA | 2009 | Mol Ce112009，33，6： | 1 |
| 2 | An architectural role for a nuclear noncoding RNA:NEAT1 RNA is essential for the structure of paraspeckles显示文摘 | Clemson CM Hutchinson JN Sara SA | 2009 | Mol Cell2009，33，6： | 1 |
| 3 | An architectural role for a nuclear noncoding RNA : NEAT1 RNA is essential for the structure of parapeckles 显示文摘 | Clemson CM Hutchinson JN Sara SA | 2009 | Mol Cell2009，33，6： | 1 |
| 4 | A salmonella typhi OmpC fusion protein expressing the CD154 Trp140-Ser149 amino acid strand binds CD40 and actives a lymphoma B-cell line显示文摘 | Mario I Vega Leopoldo SA Sara HY | 2003 | Immunology2003，110，： | 1 |
| 5 | An architectural role for a nuclear noncoding RNA: NEAT1 RNA is essential for the structure of paraspeckles 显示文摘 | Clemson CM Hutchinson JN Sara SA | 2009 | Mol Ce112009，33，6： | 1 |
| 6 | Bilateral suddensensorineural hearing loss:review显示文摘 | Sara SA Teh BM Friedland P | 2014 | J Laryngol Otol2014，128，1： | 1 |
| 7 | Selective silencing of 2Cys and type-ⅡB Peroxiredoxins discloses their roles in cell redox state and stress signaling显示文摘Peroxiredoxins(Prx) catalyse the reduction of hydrogen peroxide(H2O2) and, in association with catalases and other peroxidases, may participate in signal transduction by regulating intercellular H2O2 concentration that in turn can control gene transcription and cell signaling. Using virusinduced-gene-silencing(VIGS), 2-Cys Peroxiredoxin(2Cys Prx)family and type-II Peroxiredoxin B(Prx IIB) gene were silenced in Nicotiana benthamiana, to study the impact that the loss of function of each Prx would have in the antioxidant system under control(22 °C) and severe heat stress conditions(48 °C). The results showed that both Prxs, although in different organelles,influence the regeneration of ascorbate to a significant extent,but with different purposes. 2Cys Prx affects abscisic acid(ABA)biosynthesis through ascorbate, while Prx IIB does it probablythrough the xanthophyll cycle. Moreover, 2Cys Prx is key in H2O2 scavenging and in consequence in the regulation of ABA signaling downstream of reactive oxygen species and Prx IIB provides an important assistance for H2O2 peroxisome scavenges. | Patrícia Vidigal Ana Montserrat Martin-Hernandez Cèlia Guiu-Aragonés Sara Amncio Luísa Carvalho | 2015 | Journal of Integrative Plant Biology2015，57，6： | 1 |
| 8 | An architec- tural role for a nuclear noncoding RNA:NEATl RNA is es- sential for the structure of paraspeckles显示文摘 | Clemson CM Hutchinson JN Sara SA | 2009 | Mol Cell2009，33，： | 1 |
| 9 | Follow up evaluation of a high school eating disorders screening program: knowledge, awareness and self-referral显示文摘 | Cheryl MD Sara FF Bryn SA | 2005 | J Adolescent Health2005，36，3： | 1 |
| 10 | An architectural role for a nuclear noncoding RNA:NEATl RNA is essential for the structure of paraspeckles 显示文摘 | Clemson CM Hutchinson JN Sara SA | 2009 | Mol Cell2009，33，6： | 1 |
| 11 | An architecturalrole for a nuclear noncoding RNA : NEAT1 RNA is essential forthe structure of paraspeckles显示文摘 | Clemson CM Hutchinson JN Sara SA | 2009 | Mol Cell2009，33，6： | 1 |
| 12 | Ammonia-oxidizing communities in agricultural soil incubated with organic waste residues显示文摘 | Karin Nyberg Anna Schnürer Ingvar Sundh ?sa Jarvis Sara Hallin | 2006 | Biology and Fertility of Soils2006，，4： | 1 |
| 13 | Neutropenic Fever in Lung Cancer:Clinical Aspects Related to Mortality and Antibiotic Failure显示文摘Background and objectives:Lung cancer(LC)is the leading cause of cancer death.Patients treated with chemotherapy are at risk of developing chemotherapy-induced febrile neutropenia(FN),a potentially life-threatening complication.The aims of this study were(1)to characterize FN admissions of patients with LC in a pulmonology department,and(2)to determine associations between patient profiles,first-line antibiotic failure(FLAF)and mortality.Methods:Retrospective observational case-series,based on the analysis of medical records of LC patients that required hospitalization due to chemotherapy-induced FN.Results:A total of 42 cases of FN were revised,corresponding to 36 patients,of which 86.1%were male,with a mean age of 66.71±9.83 years.Most patients had a performance status(PS)equal or less than 1,and metastatic disease was present in 40.5%(n=17).Respiratory tract infections accounted for 42.9%(n=18)of FN cases,and multidrug-resistant Staphylococcus aureus was the most isolated agent.The mortality rate was 16.7%(n=7),and the FLAF was 26.2%(n=11).Mortality was associated with a PS≥2(P=0.011),infection by a Gram-negative agent(P=0.001)and severe anemia(P=0.048).FLAF was associated with longer hospitalizations(P=0.020),PS≥2(P=0.049),respiratory infections(P=0.024),and infection by a Gram-negative(P=0.003)or multidrug-resistant agent(P=0.014).Conclusions:Lower PS,severe anemia,and infections by Gram-negative or multi-resistant agents seem to be associated with worse outcomes in FN patients. | Inês RODRIGUES Luísa NASCIMENTO Ana Cláudia PIMENTA Sara RAIMUNDO Bebiana CONDE Ana FERNANDES | 2021 | 中国肺癌杂志2021，24，11： | 0 |
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