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| 1 | Effect of Shoushen granule on arterial elasticity in patients with carotid atherosclerosis:a clinical randomized controlled trial显示文摘OBJECTIVE: To investigate the effectiveness of Shoushen granule,Chinese herbal preparation,on carotid artery elasticity in patients with carotid atherosclerosis.METHODS: The total of 156 carotid atherosclerosis patients were randomly divided into the intervention group(83 cases,treated with Shoushen granule) and the control group(73 cases,treated with pravastatin). Brachial-ankle pulse wave velocity(ba PWV) and Ankle-Brachial Pressure Index(ABI)were measured by automated arteriosclerosis detector. The changes of common carotid artery intima-media thickness(IMT) and parameters of the carotid artery elasticity in patients,including stiffness parameter(β),pressure-strain elastic modulus(Ep),arterial compliance(Ac),augmentation index(AI),and pulse wave velocity β(PWVβ) were detected by Echo-Tracking(ET) technique before and after 24 week treatment. In the meantime,levels of blood lipid,and liver and renal function were measured respectively.RESULTS: After 24 weeks,ba PWV,IMT and parameters of the carotid artery elasticity(β,Ep,AI and PWVβ) were markedly decreased in intervention group compared with those of before treatment(P < 0.01),but the level of Ac was increased significantly(P < 0.01). And there were no significant differences compared with control group on the same period(P > 0.05).CONCLUSION: In this pilot study,it was demonstrated ET technology and automated arteriosclerosis detector could be used to evaluate carotid artery elasticity effectively,and the action of Shoushen granule on carotid atherosclerosis might be related to the regulation of carotid artery elasticity. | Shen Dingzhu Xing Sanli Chen Chuan Shen Rui Lou Danfei | 2015 | Journal of Traditional Chinese Medicine2015，35，4： | 15 |
| 2 | KAP Survey of Turkish University Students on Sexuality,reproductive Health,Drug Addiction and Violence显示文摘Objective To investigate the attitudes, behaviours and reflections of the university students, on sexuality, reproductive health, violence, smoking, alcohol and drug use, and to find out their expectations from a youth health service. Methods A total of 5 300 students (1 880 girls, 3 420 boys) from various faculties of Kyrykkale University were enrolled into this cross-sectional study. Students com- pleted the self-administered questionnaire as one of the researchers was present at the classroom. Research monitors five categories of priority health-risk behaviours among youth and young adults. Results Mean age of 3 420 male (64.5%) and 1 880 female (35.5%) students were 20.3 years. Among all 4 380 (82.9%) students [1 350 girls (71.8%), 3 030 boys (88.5%)] had some kinds of information about sexuality, however this dropped to 2 730 students (51.5%) within the context of adequacy. Friends were the major source (34%) for the first information on sexuality. Using a condom was the mostly heard method of contraception (46.9%) and interestingly 1.1% of the students had no knowledge on any of the protection methods. Among all 25.3% of the students (33.0% boys, 11.4% girls) had some kind of sexual intercourse, and within this group 58.8% experienced his/her first sexual relationship at 18 years of age and over; 53.9% were protected in all intercourses. Using a condom was the main way of protection for boys (63.7%) and pills were for the girls (73.9%). None of the female students mentioned having an abortion but 8% had friends who had undergone abortion. Tobacco use was 35.1% among the group, and 8.7% of the male and 3.6% of the female students were using drugs. Although 67.4% students claimed they never witnessed violence between their parents, 43.2% witnessed violence among their siblings, 67.0% beween friends, 72.6% in the streets and 64.2% in the school. About 30.0% of the students reported having weight problems, and 14.7% admitted visiting a doctor for that problem. If there would be a service provided for the adolescents in the university, 67% of thestudents would attend in case of a problem. Past experiences were important for us and we saw that among all 8% of the participants had some kind of sexual problem, within this group 50.7% felt uncomfortable during the visit and only 60.4% were satisfied with the care of the physician. Conclusion Our study results show the current situation of adolescents in Kyrykkale University and will be used to improve policies and programs to reduce priority health- risk behaviours among youth of our and surrounding provinces and establish a youth friendly service in Kyrykkale University within this purposes. | H■zel Selda Sanli Cihat Albayrak Meryem Fidan Serdar Agar Ayca | 2006 | Journal of Reproduction and Contraception2006，17，4： | 4 |
| 3 | Efficacy of Shoushen granule on adenosine triphosphate binding cassette transporter A1, proprotein convertase subtilisin/kexin type 9 and toll-like receptor 4/nuclear factor kappa-B signaling pathway in ApoE-knockout mice显示文摘OBJECTIVE: To evaluate the efficacy of Shoushen granule, prepared with four Chinese medicinals, on the targeted regulation of adenosine triphosphate binding cassette transporter A1(ABCA1) through proprotein convertase subtilisin/kexin type 9(PCSK9) and toll-like receptor 4(TLR4)/nuclear factor kappa-B(NF-κB) signaling pathway to affect atherosclerosis(AS) in ApoE-knockout(ApoE-/-) mice.METHODS: ApoE-/-mice fed with a high-fat diet were used for AS modeling and divided into Model,Shoushen, and Atorvastatin groups. C57 BL/6 J mice at the same age and background strain were included in the Control group. Western blot and immunohistochemistry were used to measure ABCA1, PCSK9, TLR4, and NF-κB protein expression in mouse aortas. Enzyme-linked immuno sorbent assay was used to measure mouse serum tumor necrosis factor-α(TNF-α), interleukin-10(IL-10), monocyte chemoattractant protein 1(MCP-1), and intercellular cell adhesion molecule-1(ICAM-1) expression. Serum lipid profiles and histopathology were also assessed. Shoushen granule were composed of Heshouwu(Radix Polygoni Multiflori) 15 g, Gouqizi(Fructus Lycii) 15 g, Sheng shanzha(Raw Fructus Crataegus Pinnatifidae) 10 g, and Sanqi(Radix Notoginseng) 3 g.RESULTS: ApoE-/-mice fed with a high-fat diet had notable AS lesions, with reduced ABCA1 and IL-10 levels, elevated PCSK9, TLR4, NF-κB, TNF-α, MCP-1,and ICAM-1 expression, and increased total cholesterol(TC) and low density lipoprotein cholesterol(LDL-C) contents. With drug interventions, the areas of AS plaques were significantly reduced,the ABCA1 and IL-10 levels were increase, while the PCSK9, TLR4, NF-κB, TC, and LDL-C contents,and the TNF-α, MCP-1, and ICAM-1 expression were reduced.CONCLUSION: Shoushen granule effectively interfered with AS development by antagonizing the expression of key factors of the PCSK9 and TLR4/NF-κB signaling pathway to upregulate ABCA1 expression. | Li Shanshan Cao Hui Shen Dingzhu Chen Chuan Xing Sanli Dou Fangfang Jia Qingling | 2019 | Journal of Traditional Chinese Medicine2019，39，4： | 4 |
| 4 | Solar fuel from photo-thermal catalytic reactions with spectrum-selectivity: a review显示文摘太阳的燃料是精力以后采购的理想之一。相片和热效果的协同作用在相对温和的条件下面导致一条新途径到更高太阳的燃料生产。这份报纸从光谱选择的相片热的合作催化作用为太阳的燃料生产考察不同途径。评论以光谱选择和相片热的催化作用的合作效果,和机制的意思开始。从一个技术观点,然后,很多个试验性或理论的工作被化学反应和使用的牺牲的试剂排序。另外,这些工作基于操作条件,光谱选择,材料,和生产率被总结并且公布。讨论最后与光谱选择有关相片热的催化反应的未来开发被介绍。 | Sanli TANG Jie SUN Hui HONG Qibin LIU | 2017 | Frontiers in Energy2017，11，4： | 3 |
| 5 | Bushen Jiangzhi formula reduces atherosclerosis in apoE-/-mice through autophagy显示文摘OBJECTIVE:To study the effect of Bushen Jiangzhi formula(BSJZF)on atherosclerosis(AS)in apolipoprotein E knockout(apoE^-/-)mice and the underlying mechanism.METHODS:We used a high fat diet to induce AS in apoE^-/- mice.The mice were randomly divided into four groups:model,BSJZF,atorvastatin,and 3-methyladenine groups.Syngeneic C57BL/6 mice of the same age were used for the control group.Autophagosomes in the aorta were examined by transmission electron microscopy.Morphology,lipid accumulation,and collagen deposition in the aorta were examined by hematoxylin and eosin,Oil Red O,and Masson's staining,respectively.Serum levels of tumor necrosis factor alpha(TNF-α),interferon gamma(IFN-γ),and interleukin 10(IL-10)were measured by enzyme-linked immunoassays.Protein expression of microtubule-associated protein light chain 3(LC3),Beclin 1,and p62 in the aorta were examined by Western blot analyses.RESULTS:ApoE^-/- mice fed a high fat diet exhibited AS symptoms including less autophagosomes in the aorta,higher serum levels of TNF-α,IFN-γ,and p62,and lower serum levels of IL-10,LC3,and Beclin 1.Treatment with BSJZF significantly reduced the area of the aortic plaque,decreased expression of TNF-α,IFN-γ,and p62,and increased expression of IL-10,LC3,and Beclin 1.CONCLUSION:Our findings suggest that BSJZF promotes autophagy and reduces inflammation by regulating the expression of autophagy-related proteins LC3,Beclin 1,and p62,thereby effectively treating AS. | Cao Hui Jia Qingling Shen Dingzhu Yan Li Chen Chuan Xing Sanli Dou Fangfang | 2020 | Journal of Traditional Chinese Medicine2020，40，4： | 3 |
| 6 | Arsenic trioxide-mediated cytotoxicity and apoptosis in proatate and ovarian carcinoma cell lines显示文摘 | Sanli U A Ezgin C | 2000 | Clin Cancer Res2000，6，12： | 1 |
| 7 | The lnfluence of Engine Speed and Load on the Heat Transfer between Gases and In-cylinder Walls at Fired and Motored Conditions of an IDI Diesel Engine显示文摘 | SANLI A OZSEZEN A N KILICASLAN I | 2008 | Applied Thermal Engineering2008，28，： | 1 |
| 8 | Lovastatin sensitizes lung cancercells to ionizing radiation:modulation of molecular pathways of radioresistance and tumor suppression显示文摘 | Sanli T Liu C Rashid A | 2011 | J Thorac Oncol2011，6，3： | 1 |
| 9 | Mycosis fungoides in a patient with ankylosing spondylitis during infliximab therapy显示文摘 | Sanli H Ataman S Akay BN | | 0，，： | 1 |
| 10 | Anxiety,depression,and nature of acne vulgaris in adolescents显示文摘 | Aktan S Ozmen E Sanli B | 2000 | Int J Dermatol2000，39，5： | 1 |
| 11 | Effect of using transglutaminase on physical, chemical and sensory properties of set-type yoghurt显示文摘 | Sanli T Sezgin E Deveci O | 2011 | Food Hydrocolloids2011，25，6： | 1 |
| 12 | Displacement of electrodes of a cochlear implant into the vestibular system : intra- and postoperative electrophysiological analyses显示文摘 | Pau H Parker A Sanli H | 2005 | Acta Otolaryngol2005，125，10： | 1 |
| 13 | Virtual bronchoscopy using FDG-PET/CT images for the evaluation of lung cancer 显示文摘 | Yildirim D Tamam M Sanli Y | 2012 | Eur Rev Med Pharmacol Sci2012，16，14： | 1 |
| 14 | Vitiligo after hematopoietic cell transplantation:six cases and review of the literature显示文摘 | Sanli H Akay BN Arat M | 2008 | Dermatology2008，216，4： | 1 |
| 15 | Comparison of the perfor- mance of TK system with LJ and MGIT methods in the diagnosis of tuberculosis显示文摘 | Feyzioglu B Dogan M Sanli OO | 2014 | Int J Clin Exp Med2014，7，4： | 1 |
| 16 | Graft materials of Peyronier's disease surgery:a comprehensive review显示文摘 | Kadioglu A Sanli O Akman T | 2007 | J Sex Med2007，4，3： | 1 |
| 17 | Peritumoral brain edema in int raeranial meningiomas显示文摘 | Gurkanlar D Er U Sanli M | 2005 | J Clin Neurosci2005，12，7： | 1 |
| 18 | The role of round window electrophysiological techniques in the seliction of children for cochlear implants显示文摘 | GIBSON W SANLI H | 2000 | Adv Otorhinolaryngol2000，57，： | 1 |
| 19 | Peritumoral brain edema in intracranial meningiomas显示文摘 | Gurkanlar D Er U Sanli M | 2005 | J Clin Neurosci2005，12，7： | 1 |
| 20 | Arsenic trioxide-mediated cytotoxicity and apoptosis in proatate and ovarian carcinoma cell lines显示文摘 | USLU R SANLI UA SEZGIN C | 2000 | Clin Cancer Res2000，6，12： | 1 |
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