|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Endoscopic management of postoperative bile leaks显示文摘BACKGROUND: Significant bile leak as an uncommon complication after biliary tract surgery may constitute a serious and difficult management problem. Surgical management of biliary fistulae is associated with high morbidity and mortality. Biliary endoscopic procedures have become the treatment of choice for management of biliary Gstulae. METHODS: Ninety patients presented with bile leaks after cholecystectomy ( open cholecystectomy in 45 patients, cholecystectomy with common bile duct exploration in 20 and laparoscopic cholecystectomy in 25). The presence of bile leaks was confirmed by ERCP and the appearance of bile in percutaneous drainage of abdominal collections. Of the 90 patients with postoperative bile leaks, 18 patients had complete transaction of the common bile duct by ERCP and were subjected to bilioenteric anastomosis. In the remaining patients after cholangiography and localization of the site of bile leaks. therapeutic procedures like sphinctero-tomy, biliary stenting and nasobiliary drainage ( NBD ) were performed. If residual stones were seen in the common bile duct, sphincterotomy was followed by stone extraction using dormia basket. Nasobiliary drain or stents of 7F size were placed according to the standard techniques. The NBD was removed when bile leak stopped and closure of the fistula confirmed cholangiographically. The stents were removed after an interval of 6-8 weeks. RESULTS: Bile leaks in 72 patients occurred in the cystic duct (38 patients), the common bile duct (30 ), and the right hepatic duct (4). Of the 72 patients with post-operative bile leak, 24 had associated retained common bile duct stones and 1 had ascaris in common bile duct. All the 72 patients were subjected to therapeutic procedures including sphincterotomy with stone extraction followed by biliary stenting (24 patients), removal of ascaris and biliary stenting (1), sphincterotomy with biliary stenting (18), sphincterotomy with NBD (12), biliary stenting alone (12), and NBD alone (5). Bile leaks stopped in all patients at a median interval of 3 days (range 3-16 days) after endoscopic in- terventions. No difference was observed in efficacy and in time for the treatment of bile leak by sphincterotomy with endoprosthesis or endoprosthesis alone in patients with bile leak after surgery. CONCLUSIONS: Post-cholecystectomy bile leaks occur most commonly in the cystic duct and associated common bile duct stones are found in one-third of cases. Endoscopic therapy is safe and effective in the management of bile leaks and fistulae after surgery. Sphincterotomy with endoprosthesis or endoprosthesis alone is equally effective in the management of postoperative bile leak. | Naresh Agarwal Barjesh Chander Sharma Sanjay Garg Rakesh Kumar Shiv K Sarin | 2006 | Hepatobiliary & Pancreatic Diseases International2006，5，2： | 33 |
| 2 | One fifth of hospitalizations for peptic ulcer-related bleeding are potentially preventable显示文摘AIM:To calculate the proportion of potentially preventable hospitalizations due to peptic ulcer disease(PUD),erosive gastritis(EG)or duodenitis(ED).METHODS:Retrospective cohort study using ICD-10codes to identify all patients with upper gastrointestinal hemorrhage secondary to endoscopically proven PUD,EG or ED during the period from March 2007 to October 2010 in three major metropolitan hospitals in Melbourne,Australia.Patients were divided into'high risk'(those who would benefit from gastroprotection)and'not high risk'groups as defined by established guidelines.Mean Rockall score,transfusion requirement,length of stay,rebleeding rates,need for surgery and in-hospital mortality was compared between'high risk'and'not high risk'groups.Within the'high risk'group,those on gastroprotection and those with no gastroprotection were also compared.RESULTS:Five hundred and seven patients were included for analysis of which 174 were classified as high risk.Median values of complete Rockall Score(5vs 4,P=0.002)and length of stay(5 d vs 4 d,P=0.04)were higher in the high risk group but in-hospital mortality was lower(0.6%vs 3.9%,P=0.03).130out of the 174 patients in the high risk group were not taking recommended gastroprotective therapy prior to hospitalization.Past history of PUD(OR=3.7,P=0.006)and clopidogrel use(OR=3.2,P=0.007)significantly predicted prescription of gastroprotective therapy.Using proton pump inhibitor protection rates of 50%-85%from published studies,an estimation of13%to 22%of the total number of the hospitalizations due to PUD or EG/ED related bleeding may have been preventable.CONCLUSION:Up to one fifth of all hospitalizations for bleeding secondary to PUD or EG/ED are potentially preventable. | Ray Boyapati Sim Ye Ong Bei Ye Anuk Kruavit Nora Lee Rhys Vaughan Sanjay Nurkar Peter Gibson Mayur Garg | 2014 | World Journal of Gastroenterology2014，20，30： | 8 |
| 3 | Comparative evaluation of microscopy,OptiMAL® and 18S rRNA gene based multiplex PCR for detection of Plasmodium falciparum & Plasmodium vivax from field isolates of Bikaner,India显示文摘Objective:To evaluate microscopy,OptiMAL? and multiplex PCR for the identification of Plasmodium falciparum(P.falciparum) and Plasmodium vivax(P.vivax) from the field isolates of Bikaner,Rajasthan(Northwest India).Methods:In this study,a multiplex PCR(P.falciparum and P.vivax) was further developed with the incorporation of Plasmodium malariae(P.malariae) specific primer and also a positive control.The performance of microscopy,plasmodium lactate dehydrogenase(pLDH) based malaria rapid diagnostic test OptiMAL? and 18S rRNA gene based multiplex PCR for the diagnosis of P.falciparum and P.vivax was compared.Results:The three species multiplex PCR if.falciparum,P.vivax and P.malariae) with an inbuilt positive control was developed and evaluated.In comparison with multiplex PCR,which showed the sensitivity and specificity of 99.36%(95%CI,98.11%-100.00%) and 100.00%(95%CI,100.00%-100.00%),the sensitivity and specificity of microscopy was 90.44%(95%CI,88.849-95.04%) and 99.22%(95% CI,97.71%-100.00%),and OptiMAL? was 93.58%(95%CI,89.75%-97.42%) and 97.69%(95%CI, 95.10%-100.00%).The efficiencies were 99.65%,95.10%and 95.45%for multiplex PCK.microscopy and OptiMAL?.respectively.Conclusions:Our results raise concerns over the overall sensitivities of microscopy and OptiMAL?,when compared to the multiplex PCR and thus stress the need for new molecular interventions in the accurate detection of the malarial parasites.This further highlights the fact that further developments are needed to improve the performance of rapid diagnostic tests at field level. | Deepak Pakalapati Shilpi Garg Sheetal Middha Abhishek Kochar Amit Kumar Subudhi Boopathi Pon Arunachalam Sanjay Kumar Kochar Vishal Saxena Pareek RP Jyoti Acharya Dhanpat Kumar Kochar Ashis Das | 2013 | Asian Pacific Journal of Tropical Medicine2013，6，5： | 3 |
| 4 | Herbal medicines for sexually transmitted diseases and AIDS显示文摘 | Kavita Vermani Sanjay Garg | 2002 | Journal of Ethnopharmacology2002，，1： | 1 |
| 5 | European Journal of Pharma ceutics and Bioph-armaceutics显示文摘 | Rajan K Vermal Sanjay Garg | 2004 | 57:5]3-5252004，57，： | 1 |
| 6 | Effect of wet milling process on the solid state of indomethacin and simvastatin 显示文摘 | Sharma Puneet Denny William A Garg Sanjay | 2009 | International Journal of Pharmaeeutics2009，380，12： | 1 |
| 7 | Robust eigenspace assignment using singular value sensitivities显示文摘 | GARG Sanjay | 1991 | Journal of Guidance Control and Dynamics1991，14，2： | 1 |
| 8 | Acute pancreatitis with CMV papillitis and cholangiopathy in a renal transplant recipient显示文摘 | Bagchi Soumita Kamalkumar Sanjay Kumar Agarwal Pramod Garg Amit Dinda Suresh Chand Tiwari | 2009 | Clinical and Experimental Nephrology2009，，4： | 1 |
| 9 | The dissolution of benzene, toluene, m-xylene and naphthalene from a residually trapped non-aqueous phase liquid under mass transfer limited conditions显示文摘 | Sanjay Garg William G. Rixey | 1999 | Journal of Contaminant Hydrology1999，，3： | 1 |
| 10 | Turbofan engine control design using robust multivariable control technologies 显示文摘 | Dean K Frederick Sanjay Garg Shrider Adibhatla | 2000 | IEEE Transactions on Control Systems Technology2000，8，6： | 1 |
| 11 | Hydrogels:from controlled release to PH responsive drug delivery显示文摘 | Piyush Gupta Kavita Vermani and Sanjay Garg | 2002 | Drug Discovery Today2002，7，： | 1 |
| 12 | A simplified scheme for scheduling multivariable controllers显示文摘 | Sanjay Garg | 1997 | IEEE Control Systems1997，，： | 1 |
| 13 | Turbo- fan Engine Control Design Using Robust Muhivariable Control Technologies显示文摘 | Dean K Frederick Sanjay Garg Shrider Adibhatla | | 0，，06： | 1 |
| 14 | Robust Integrated Flight/Propulsion Control Design for a STOVL Aircraft Using H-Infinity Control Design Techniques 显示文摘 | Sanjay Garg | 1993 | Automatics1993，29，1： | 1 |
| 15 | Concomitant allergic bronchopulmonary aspergillosis and allergic fungal sinusitis显示文摘 | Prasad R Garg R Sanjay | 2007 | Indian J Med Sci2007，61，9： | 1 |
| 16 | A simplified scheme for scheduling multivariable controllers显示文摘 | Sanjay Garg | 1997 | IEEE Control Systems1997，，： | 1 |
| 17 | A validated high performance liquid chromatographic method for analysis of nicotine in pure form and from formulations显示文摘 | Tambwekar Kaustubh R Kakariya Ritesh B Garg Sanjay | 2003 | Journal of Pharmaceutical and Biomedical Analysis2003，32，3： | 1 |
| 18 | Formulation aspects in the development of osmotically controlled oral drug delivery systems显示文摘 | Rajan K Verma Divi Murali Krishna Sanjay Garg | 2002 | Journal of Controlled Release2002，，1： | 1 |
| 19 | Allergic bronchopulmonary as- pergillosis: A review of 42 patients from a tertiary care center in India显示文摘 | Prasad R Garg R Sanjay | 2009 | Lung India2009，26，2： | 1 |
| 20 | Hydrogels : from con- trolled release to pH-responsive drug delivery 显示文摘 | Piyush Gupta Kavita Vermani Sanjay Garg | 2002 | DDT2002，10，7： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员