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18篇 您的检索式:作者名="Sanchez Martin P"
    题名 作者 年代 出处 被引量
1The role of gut microbiota(commensal bacteria)and the mucosal barrier in the pathogenesis of inflammatory and autoimmune diseases and cancer:contribution of germ-free and gnotobiotic animal models of human diseases显示文摘Metagenomic approaches are currently being used to decipher the genome of the microbiota(microbiome),and,in parallel,functional studies are being performed to analyze the effects of the microbiota on the host.Gnotobiological methods are an indispensable tool for studying the consequences of bacterial colonization.Animals used as models of human diseases can be maintained in sterile conditions(isolators used for germ-free rearing)and specifically colonized with defined microbes(including non-cultivable commensal bacteria).The effects of the germ-free state or the effects of colonization on disease initiation and maintenance can be observed in these models.Using this approach we demonstrated direct involvement of components of the microbiota in chronic intestinal inflammation and development of colonic neoplasia(i.e.,using models of human inflammatory bowel disease and colorectal carcinoma).In contrast,a protective effect of microbiota colonization was demonstrated for the development of autoimmune diabetes in non-obese diabetic(NOD)mice.Interestingly,the development of atherosclerosis in germ-free apolipoprotein E(ApoE)-deficient mice fed by a standard low-cholesterol diet is accelerated compared with conventionally reared animals.Mucosal induction of tolerance to allergen Bet v1 was not influenced by the presence or absence of microbiota.Identification of components of the microbiota and elucidation of the molecular mechanisms of their action in inducing pathological changes or exerting beneficial,disease-protective activities could aid in our ability to influence the composition of the microbiota and to find bacterial strains and components(e.g.,probiotics and prebiotics)whose administration may aid in disease prevention and treatment.Helena Tlaskalova-Hogenova Renata Stepankova Hana Kozakova Tomas Hudcovic Luca Vannucci Ludmila Tuckova Pavel Rossmann TomasHrncır Miloslav Kverka Zuzana Zakostelska Klara Klimesova Jaroslava Pribylova Jirina Bartova Daniel Sanchez Petra Fundova Dana Borovska Dagmar Sru˚tkova Zdenek Zıdek Martin Schwarzer Pavel Drastich David P Funda 2011Cellular & Molecular Immunology2011,8,2:47
2Estimating conjectural variations for electricity market models 显示文摘Lopez de Haro S Sanchez Martin P de la Hoz Ardiz J E 2007European Journal of Operational Research2007,181,3:1
3The major genetic determinants of HIV-1control affect HLA class I peptide presentation显示文摘International HIV Controllers Study Pereyra F Jia X McLaren P J Telenti A de Bakker P I Walker B D Ripke S Brumme C J Pulit S L Carrington M Kadie C M Carlson J M Heckerman D Graham R R Plenge R M Deeks S G Gianniny L Crawford G Sullivan J Gonzalez E Davies L Camargo A Moore JM Beattie N Gupta S Crenshaw A Burtt N P Guiducci C Gupta N Gao X Qi Y Yuki Y Piechocka-Trocha A Cutrell E Rosenberg R Moss K L Lemay P O'Leary J Schaefer T Verma P Toth I Block B Baker B Rothchild A Lian J Proudfoot J Alvino D M Vine S Addo M M Allen T M Altfeld M Henn M R Le Gall S Streeck H Haas D W Kuritzkes D R Robbins G K Shafer R W Gulick R M Shikuma C M Haubrich R Riddler S Sax P E Daar E S Ribaudo H J Agan B Agarwal S Ahern R L Allen B L Altidor S Altschuler E L Ambardar S Anastos K Anderson B Anderson V Andrady U Antoniskis D Bangsberg D Barbaro D Barrie W Bartczak J Barton S Basden P Basgoz N Bazner S Bellos N C Benson A M Berger J Bernard N F Bernard A M Birch C Bodner S J Bolan R K Boudreaux E T Bradley M Braun J F Brndjar J E Brown S J Brown K Brown S T Burack J Bush LM Cafaro V Campbell O Campbell J Carlson R H Carmichael J K Casey K K Cavacuiti C Celestin G Chambers S T Chez N Chirch L M Cimoch P J Cohen D Cohn LE Conway B Cooper D A Cornelson B Cox D T Cristofano M V Cuchural G Jr Czartoski J L Dahman J M Daly J S Davis B T Davis K Davod S M DeJesus E Dietz C A Dunham E Dunn M E Ellerin T B Eron J J Fangman J J Farel C E Ferlazzo H Fidler S Fleenor-Ford A Frankel R Freedberg K A French N K Fuchs JD Fuller J D Gaberman J Gallant J E Gandhi R T Garcia E Garmon D Gathe J C Jr Gaultier C R Gebre W Gilman F D Gilson I Goepfert P A Gottlieb M S Goulston C Groger R K Gurley T D Haber S Hardwicke R Hardy W D Harrigan P R Hawkins T N Heath S Hecht F M Henry W K Hladek M Hoffman R P Horton J M Hsu R K Huhn G D Hunt P Hupert M J Illeman M L Jaeger H Jellinger R M John M Johnson J A Johnson K L Johnson H Johnson K Joly J Jordan W C Kauffman C A Khanlou H Killian R K Kim A Y Kim D D Kinder C A Kirchner J T Kogelman L Kojic E M Korthuis P T Kurisu W Kwon D S LaMar M Lampiris H Lanzafame M Lederman M M Lee D M Lee J M Lee M J Lee E T Lemoine J Levy J A Llibre J M Liguori M A Little S J Liu A Y Lopez A J Loutfy M R Loy D Mohammed D Y Man A Mansour M K Marconi V C Markowitz M Marques R Martin J N Martin H L Jr Mayer K H McElrath M J McGhee T A McGovern B H McGowan K McIntyre D Mcleod GX Menezes P Mesa G Metroka CE Meyer-Olson D Miller A O Montgomery K Mounzer K C Nagami E H Nagin I Nahass R G Nelson M O Nielsen C Norene D L O'Connor D H Ojikutu B O Okulicz J Oladehin O O Oldfield E C Olender S A Ostrowski M Owen WF Jr Pae E Parsonnet J Pavlatos A M Perlmutter A M Pierce M N Pincus J M Pisani L Price L J Proia L Prokesch R C Pujet H C Ramgopal M Rathod A Rausch M Ravishankar J Rhame F S Richards C S Richman D D Rodes B Rodriguez M Rose R C 3rd Rosenberg E S Rosenthal D Ross P E Rubin D S Rumbaugh E Saenz L Salvaggio M R Sanchez WC Sanjana V M Santiago S Schmidt W Schuitemaker H Sestak P M Shalit P Shay W Shirvani V N Silebi V I Sizemore J M Jr Skolnik P R Sokol-Anderson M Sosman J M Stabile P Stapleton J T Starrett S Stein F Stellbrink H J Sterman FL Stone V E Stone D R Tambussi G Taplitz R A Tedaldi E M Telenti A Theisen W Torres R Tosiello L Tremblay C Tribble M A Trinh P D Tsao A Ueda P Vaccaro A Valadas E Vanig T J Vecino I Vega V M Veikley W Wade B H Walworth C Wanidworanun C Ward D J Warner D A Weber R D Webster D Weis S Wheeler D A White D J Wilkins E Winston A Wlodaver C G van't Wout A Wright D P Yang O O Yurdin D L Zabukovic B W Zachary K C Zeeman B Zhao M 2010Science2010,330,6010:1
4Role of prostaglandins and nitric oxide in gastrio damage induced by metamizol in rats显示文摘 Martin M J Ortiz P 2002Inflamm Res2002,51,8:1
5Role of prostaglandins and nitric oxide in gastric damage induced by metamizol in rats 显示文摘Sanchez S Martin MJ Ortiz P 2002Inflamm Res2002,51,8:1
6Effect of lipophilicity at N-1 on activity of fluoroquinolones against mycobacteria 显示文摘Thomas E Renau Joseph P Sanchez Martin A Shapiro 1995J Med Chem1995,38,:1
7Genetic relationships among species of the genus Diplotaxis (Brassieaceae) using intersimple sequence repeat markers 显示文摘MARTIN J P SANCHEZ YELAMO M D 2000Theoretical and Applied Genetics2000,101,8:1
8Genetic relationship among species of the genus Diplotaxis (Brassicaceae) using intersimple-sequence repeat markers显示文摘Martin J P Sanchez M D 2000Theory Apple Genet2000,101,:1
9Managing non- homogeneous information in group decision making 显示文摘Herrera F Martines L Sanchez P 2005European Journal of Operational Research2005,166,1:1
10Use of sequence -tagged microsatellite site markers for characterizing table grape eultivars显示文摘Sanchez - Escribano E M Martin J P Carreno J Cenis J L 1999Genome1999,42,:1
11Role of prostaglandins and nitric oxide in gastric damage induced by metamizol in rats显示文摘SANCHEZ S MARTIN MJ ORTIZ P 2002Inflamm Res2002,51,8:1
12Electrochemilumines-cencc-based odetection f beta-laetam antibiotics and beta-lac-tamases显示文摘Liang P Sanchez R I Martin M T 1996Anal Chem1996,68,14:1
13Modulation of the endogenous opioid system after morphine self - administration and during its extinction: a study in Lewis and Fischer 344 rats 显示文摘Sanchez - Cardoso P Higuera - Matas A Martin S 2007Neuropharmacology2007,52,3:1
14Barthel Index - En- hanced Feedback for Effective Cardiac Treatment ( BI - EFFECT) study: Contribution of the barthel index to the heart failure risk scoring system model in elderly adults with acute heart failure in the emergency department 显示文摘Martin - Sanchez FJ Gil V Llorens P 2012J Am Geriatr Soe2012,60,3:1
15Sirolimus conversion after liver trans- plantation: improvement in measured glomerular filtration rate after 2 years显示文摘Sanchez E Q Martin A P Ikegami T Uemura T Narasimhan G Goldstein R M 2005Transplant Proc2005,37,:1
16Diversity of moderately halophilic bacteria producing extracellular hydrolytic enzymes显示文摘Sanchez P C Martin S Mellado E 2003Journal of Ap- plied Microbiology2003,94,:1
17Genetic relationships among species of the genus Diplotaxis (B rassicaceae) using inter simple sequence repeat markers显示文摘Martin J P Sanchez Yelamo M D 2000Theoretical and Applied Genetics2000,101,12:1
18Tumor heterogeneity: morphological, molecular and chnicalimplications显示文摘LLEONART M E MARTIN D P SANCHEZ P R 2000Histol Histopathol2000,15,3:1
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