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| 1 | Upper-gastrointestinal bleeding secondary to peptic ulcer disease:Incidence and outcomes显示文摘AIM:To evaluate the incidence,surgery,mortality,and readmission of upper gastrointestinal bleeding(UGIB)secondary to peptic ulcer disease(PUD).METHODS:Administrative databases identified all hospitalizations for UGIB secondary to PUD in Alberta,Canada from 2004 to 2010(n=7079)using the International Classification of Diseases Codes(ICD-10).A subset of the data was validated using endoscopy reports.Positive predictive value and sensitivity with 95%confidence intervals(CI)were calculated.Incidence of UGIB secondary to PUD was calculated.Logistic regression was used to evaluate surgery,in-hospital mortality,and 30-d readmission to hospital with recurrent UGIB secondary to PUD.Co-variants accounted for in our logistic regression model included:age,sex,area of residence(i.e.,urban vs rural),number of Charlson comorbidities,presence of perforated PUD,undergoing upper endoscopy,year of admission,and interventional radiological attempt at controlling bleeding.A subgroup analysis(n=6356)compared outcomes of patients with gastric ulcers to those with duodenal ulcers.Adjusted estimates are presented as odds ratios(OR)with95%CI.RESULTS:The positive predictive value and sensitivity of ICD-10 coding for UGIB secondary to PUD were85.2%(95%CI:80.2%-90.2%)and 77.1%(95%CI:69.1%-85.2%),respectively.The annual incidence between 2004 and 2010 ranged from 35.4 to 41.2 per100000.Overall risk of surgery,in-hospital mortality,and 30-d readmission to hospital for UGIB secondary to PUD were 4.3%,8.5%,and 4.7%,respectively.Interventional radiology to control bleeding was performed in 0.6%of patients and 76%of these patients avoided surgical intervention.Thirty-day readmission significantly increased from 3.1%in 2004 to 5.2%in 2010(OR=1.07;95%CI:1.01-1.14).Rural residents(OR rural vs urban:2.35;95%CI:1.83-3.01)and older individuals(OR≥65 vs<65:1.57;95%CI:1.21-2.04)were at higher odds of being readmitted to hospital.Patients with duodenal ulcers had higher odds of dying(OR=1.27;95%CI:1.05-1.53),requiring surgery(OR=1.73;95%CI:1.34-2.23),and being readmitted to hospital(OR=1.54;95%CI:1.19-1.99)when compared to gastric ulcers.CONCLUSION:UGIB secondary to PUD,particularly duodenal ulcers,was associated with significant morbidity and mortality.Early readmissions increased over time and occurred more commonly in rural areas. | Samuel Quan Alexandra Frolkis Kaylee Milne Natalie Molodecky Hong Yang Elijah Dixon Chad G Ball Robert P Myers Subrata Ghosh Robert Hilsden Sander Veldhuyzen van Zanten Gilaad G Kaplan | 2014 | World Journal of Gastroenterology2014，20，46： | 21 |
| 2 | 腹腔镜外科学基础认证项目简介及其对中国外科医师的意义显示文摘腹腔镜外科学基础(FLS)项目是普通外科中第1个经过验证的操作和认知考核项目.FLS由美国胃肠内镜外科医师协会(SAGES)开发并得到美国外科医学委员会(ABS)的支持.ABS要求所有拟参加普通外科医师执业资格考试前必须通过FLS考试.在美国,普通外科医师执业资格考试是取得执业资格的第一步.本文回顾了FLS项目在美国取得的成功经验,并就该项目在中国推广标准化腹腔镜外科技术中的应用和获益进行了介绍. | Linda P Zhang Samuel R G Finlayson Allan Okrainec Steven D Schwaitzberg | 2014 | 中华消化外科杂志2014，13，9： | 5 |
| 3 | Biosynthesis of O-antigens:genes and pathways involved in nucleotide sugar precursor synthesis and O-antigen assembly显示文摘 | Samuel G Reeves P | 2003 | Carbohyd Res2003，33，： | 1 |
| 4 | Hypcrea/Trichoderma (Ascomycota,Hypocreales,Hypocreaceae):species with green ascospores显示文摘 | Samuels J G | 2003 | Study in Mycology2003，48，： | 1 |
| 5 | A Model of the Nuclear Control of Mitochondrial DNA Replication显示文摘 | Capps G J Samuels D C Chinnery P F | 2003 | Journal of Theoretical Biology2003，221，4： | 1 |
| 6 | A model of the nuclear control of mitochondrial DNA replication 显示文摘 | CAPPS G J SAMUELS D C CHINNERY P F | 2003 | Journal of Theoretical Biology2003，221，4： | 1 |
| 7 | Post-cesarean related infection and vaginal preparation with povidone-iodine revisited显示文摘 | Melissa A G Samuel D P | 2002 | Prim Care Update Ob/Gyns2002，9，6： | 1 |
| 8 | Mastoparan Rapidly Activates Plant MAP Kinase Signaling Independent of Heterotrimeric G Proteins显示文摘 | MILES G P SAMUEL M A JONES A M | 2004 | Plant Physiol2004，134，4： | 1 |
| 9 | object-oriented optimization approach using genetic algorithms for lattice towers显示文摘 | Sivakumar P Rajaraman A Samuel Knight G M | 2004 | Journal of Computing in Civil Engineering2004，18，2： | 1 |
| 10 | Introduction of digestive a-amylase in larvae of Zabrotes subfasciatus (Coleoptera: Bruchidae) in response to ingestion of common bean a-amylase inhibitor 显示文摘 | Silva C P Terra W R de Sa M F G Samuels R I | 2001 | Journal of Insect Physiology2001，47，： | 1 |
| 11 | Orientation of silk Ⅲ at the air-water interface显示文摘 | Regina V Samuel P G Wayne M | 1999 | International Journal of Bio- logical Macromolecules1999，24，23： | 1 |
| 12 | Hypcrea/Trichoderma (Ascomycota,Hypocreales,Hypocreaceae):species with green ascospores显示文摘 | CHAVERRI P L SAMUELS J G | 2003 | Study in Mycology2003，，48： | 1 |
| 13 | The interaction of aromatic disulphides and sulphuric acid显示文摘 | William G P Samuel S | 1910 | J S C1910，1911，： | 1 |
| 14 | Development and validation of a prognostic nomogram for recurrence-free survival after complete surgical resection of localised primary gastrointestinal stromal tumour: a retrospective analysis显示文摘 | Jason S Gold Mithat G?nen Antonio Gutiérrez Javier Martín Broto Xavier García-del-Muro Thomas C Smyrk Robert G Maki Samuel Singer Murray F Brennan Cristina R Antonescu John H Donohue Ronald P DeMatteo | 2009 | Lancet Oncology2009，，11： | 1 |
| 15 | Phylogenetic diversty of the Rickettsiae 显示文摘 | Dobson M E Samuel J E Dasch G A Mallavia L P | 1989 | J Bacteriol1989，，： | 1 |
| 16 | Geometric mean estimation from pooled samples显示文摘 | Samuel P C Wayman E T Dinald G P | 2007 | Chemosphere2007，69，： | 1 |
| 17 | Minehuntefing by sonar in the shallow water environment显示文摘 | Nicholas P Chotirs and Samuel G Tooma | 1997 | Martime Defence1997，1997，： | 1 |
| 18 | Production of AI-( 12-25 ) wt% Si alloys by rapid solidification melt spinning versus centrifugal atomization 显示文摘 | Todeschini P Champier G Samuel F H | 1992 | Journal of Materials Science1992，27，： | 1 |
| 19 | Biosynthesis of O-antigens: genes and pathways involved in nucleotide sugar precursor synthesis and O-antigen assembly 显示文摘 | Samuel G Reeves P | 2003 | Carbohydr Res2003，338，23： | 1 |
| 20 | Novel tricyclic and tetracyclic terpanes in tertiary deltaic oils: structural identification, origin and application to petroleum correlation显示文摘 | Samuel O J Kildahl-Andersen G Nytoft H P | 2010 | Organic Geochemistry2010，41，12： | 1 |
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