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| 1 | Expression of matrix metalloproteinases 2 and 9 in human gastric cancer and superficial gastritis显示文摘AIM:To assess expression of matrix metalloproteinases 2(MMP2)and MMP9 in gastric cancer,superficial gastritis and normal mucosa,and to measure metalloproteinase activity.METHODS:MMP2 and MMP9 mRNA expression was determined by quantitative real-time polymerase chain reaction.Normalization was carried out using three different factors.Proteins were analyzed by quantitative gelatin zymography(qGZ).RESULTS:18S ribosomal RNA(18SRNA)was very highly expressed,while hypoxanthine ribosyltransferase-1(HPRT-1)was moderately expressed.MMP2 was highly expressed,while MMP9 was not detected or lowly expressed in normal tissues,moderately or highly expressed in gastritis and highly expressed in cancer.Relative expression of 18SRNA and HPRT-1 showed no significant differences.Significant differences in MMP2 and MMP9 were found between cancer and normal tissue,but not between gastritis and normal tissue.Absolute quantification of MMP9 echoed this pattern,but differential expression of MMP2 proved conflictive.Analysis by qGZ indicated significant differences between cancer and normal tissue in MMP-2,total MMP-9,250 and 110 kDa bands.CONCLUSION:MMP9 expression is enhanced in gastric cancer compared to normal mucosa;interpretation of differential expression of MMP2 is difficult to establish. | Clara Luz Sampieri Sol de la Pea Mariana Ochoa-Lara Roberto Zenteno-Cuevas Kenneth León-Córdoba | 2010 | World Journal of Gastroenterology2010，16，12： | 46 |
| 2 | Impacted Lower Third Molar Fused with a Supernumerary Tooth—Diagnosis and Treatment Planning Using Cone-Beam Computed Tomography显示文摘This paper reported a case of fusion between an impacted third molar and a supernumerary tooth, in which a surgical intervention was carried out, with the objective of removing the dental elements. The panoramic radiography was complemented by the Donovan's radiographic technique; but because of the proximity of the dental element to the mandibular ramus, it was not possible to have a final fusion diagnosis. Hence, the Cone-Beam Computed Tomography―which provides precise threedimensional information―was used to determinate the fusion diagnosis and also to help in the surgical planning. In this case report we observed that the periapical, occlusal and panoramic were not able to show details which could only be examined through the cone-beam computed tomography. | Osny Ferreira-Junior Luciana Dorigatti de .&.Aila Marcelo Bonifacio da Silva Sampieri Eduardo Dias- Ribeiro Wei-liang Chen Song Fan | 2009 | International Journal of Oral Science2009，1，4： | 11 |
| 3 | 早餐的省略和在墨西哥的胃的癌症的风险显示文摘 <Abstract>AIM: To investigate factors associated with gastric cancer (GC) in the Mexican population using a validated questionnaire. METHODS: We designed and validated in Spanish a Questionnaire to Find Factors Associated with Diseases of the Digestive Tract using GC as a model. A crosssectional study using 49 subjects, with confirmed histopathological GC diagnosis, and 162 individuals without GC participated. Odds ratio and 95% CIs were estimated in univariate and multivariate analysis adjusted for possible confounding factors. In order to match agegroups, a multivariate sub-analysis was performed in subjects ≥ 39 years of age and in females and males separately. RESULTS: In the univariate analysis, we found an association between GC and education to primary level or below, low socioeconomic status, the use of dental prostheses, omission of breakfast, consumption of very hot food and drink, addition of salt to prepared foods, consumption of salt-preserved foods and the pattern of alcohol consumption. We found protection against GC associated with the use of mouthwash, food refrigeration and regular consumption of fruit and vegetables. In the multivariate sub-analysis with subjects of ≥ 39 years, the omission of breakfast was identified as a risk factor for GC. CONCLUSION: Our study suggests an association between the omission of breakfast and the failure to refrigerate food with GC in the Mexican population. | Monserrat Verdalet-Olmedo Clara Luz Sampieri Jaime Morales-Romero Hilda Montero-L de Guevara lvaro Manuel Machorro-Castao Kenneth León-Córdoba | 2012 | World Journal of Gastrointestinal Oncology2012，4，11： | 2 |
| 4 | Matrix metalloproteinases and their tissue inhibitors in gastric cancer as molecular markers显示文摘 | Clara Sampieri Kenneth León-Córdoba José Remes-Troche | 2013 | Journal of Cancer Research and Therapeutics2013，，3： | 2 |
| 5 | The regulation of matrix metallopro- teinases and their inhibitors 显示文摘 | Clark IM Swingler TE Sampieri CL | 2008 | Int J Biochem Cell Biol2008，40，67： | 1 |
| 6 | Cancer stem cells and metastasis 显示文摘 | Sampieri K Fodde R | 2012 | Semin Cancer Bio12012，22，3： | 1 |
| 7 | Target organ damage and nonTdipping pattern defined by two sessions of ambulatory blood pressure monitoring in recently diagnosed essential hypertensive patients显示文摘 | Cuspidi C Macca G Sampieri L etal | 2001 | J Hypertens2001，19，9： | 1 |
| 8 | The regulation of matrix melalloproteinases and their inhibitors 显示文摘 | Clark IM Swingler TE Sampieri CL | 2008 | Int J Biochem Cell Biol2008，40，67： | 1 |
| 9 | STIM 1 and Orail mediate thrombin-induced Ca2+ influx in rat cortical as- trocytes 显示文摘 | Moreno C Sampieri A Vivas O | 2012 | Cell Calcium2012，52，6： | 1 |
| 10 | The regulation of matrix metalloproteinases and their inhibitors 显示文摘 | Clark IM Swingler TE Sampieri CL | 2008 | Int J Biochem Cell Biol2008，40，67： | 1 |
| 11 | Target organ damage and non- dipping pattern defined by two sessions of ambulatory blood pressure monitoring in recently diagnosed essential hypertensive patients 显示文摘 | Cuspidi C Macca G Sampieri L | 2001 | J Hypertens2001，19，9： | 1 |
| 12 | Using double-stranded RNA to prevent in vitro and in vivo viral infections by recombinant baculovirus显示文摘 | Valdes V J Sampieri A Sepulveda J | 2003 | J Biol Chem2003，278，19： | 1 |
| 13 | Target organ damage and nondipping pattern defined by two sessions of ambulatory blood pressure monitoring in recently diagnosed essential hypertensive patients显示文摘 | Cuspidi C Macca G Sampieri L | 2001 | J Hypertens2001，19，： | 1 |
| 14 | Italian Rett database and biobank显示文摘 | Sampieri K Meloni I Scala E | 2007 | Hum Mutat2007，28，4： | 1 |
| 15 | Membrane type-matrix metalloproteinases in idiopathic pulmonary fibrosis显示文摘 | García-Alvarez J Ramirez R Sampieri CL | 2006 | Sarcoidosis Vasc Diffuse Lung Dis2006，23，1： | 1 |
| 16 | Mutational screening of the RB1 gene in Italian patients with retinoblastoma reveals 11 novel mutations显示文摘 | Sampieri K Hadjistilianou T Mari F | 2006 | J Hum Genet2006，51，： | 1 |
| 17 | Target organ damage and nondipping pattern defined by two sessions of ambulatory blood pressure monitoring in recently diagnosed essential hypertensive patients 显示文摘 | Cuspidi C Macca G Sampieri L | 2001 | J Hypertens2001，19，9： | 1 |
| 18 | High prevalence of cardiac and extracardiac organ damage in refractory hypertension显示文摘 | Cuspidi C Macca G Sampieri L | 2001 | J Hypertension2001，19，： | 1 |
| 19 | Matrix metallo- proteinases and their tissue inhibitors in gastric cancer as molecular markers显示文摘 | Sampieri CL Le6n-C6rdoba K Remes-Troche JM | 2013 | J Cancer Res Ther2013，9，3： | 1 |
| 20 | Using double-stranded RNA to prevent in vitro and in vivo viral infections by recombinant bacu- lovirus显示文摘 | VALDES V J SAMPIERI A SEPULVEDA J | 2003 | The Journal of Biological Chemistry2003，278，19： | 1 |
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